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Long COVID clinical trials in Boston, MA

11 studies for Long COVID are looking for participants at sites in and around Boston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

LIFT: Life Improvement Trial

RecruitingPhase 2
  • Brigham and Women's Hospital, Boston
Ages 18 to 70 · All sexes · Updated Oct 15, 2026 · NCT06366724

A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease

RecruitingPhase 3
  • Brigham and Women's Hospital, Boston
Ages 12 and older · All sexes · Updated Oct 15, 2026 · NCT06679140

A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised

RecruitingPhase 3
  • Brigham and Women's Hospital, Boston
  • Clinical Trials Center, Boston
  • Clinical Trials Hub, Boston
Ages 18 and older · All sexes · Updated Oct 14, 2026 · NCT07013474

Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID

RecruitingPhase 3
  • Brigham and Women's Hospital, Boston
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06631287

Defibrotide for the Treatment of Severe COVID-19

RecruitingPhase 2Healthy volunteers welcome
  • Brigham and Women's Hospital, Boston
Ages 18 to 100 · All sexes · Updated Jul 20, 2026 · NCT04652115

Kisspeptin to Quantify GnRH Neuronal Function in Health and Disease

RecruitingPhase 1
  • Massachusetts General Hospital, Boston
Ages 18 to 60 · All sexes · Updated Jul 13, 2026 · NCT07224490

Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study

RecruitingPhase 3
  • Brigham and Women's Hospital, Boston
All ages · All sexes · Updated Jun 23, 2026 · NCT03808922

Positron Emission Tomography (PET) Imaging of Thrombosis

RecruitingPhase 1Healthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 to 85 · All sexes · Updated Feb 27, 2026 · NCT03830320

Mind Body Intervention for Long COVID-19

Recruiting
  • Beth Israel Deaconess Medical Center, Boston
Ages 18 to 65 · All sexes · Updated Feb 18, 2026 · NCT06045338

Influenza & COVID-19 Obstetric and Perinatal Epidemiology Study in India

RecruitingObservational study
  • Boston University School of Public Health, Global Health, Boston
Ages 18 to 50 · Women · Updated Nov 28, 2025 · NCT06168019

Sauna for Long Covid

Recruiting
  • Depression Clinical and Research Program, Boston
Ages 18 to 65 · All sexes · Updated Nov 13, 2025 · NCT05931497

About Long COVID

Anyone who has had COVID-19 can have long-lasting symptoms, know as long COVID. Learn about the symptoms and how to manage them, diagnosis, and prevention.

More about Long COVID on MedlinePlus

Long COVID trials in other cities

Other studies in Boston

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.