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Long COVID clinical trials in Durham, NC

8 studies for Long COVID are looking for participants at sites in and around Durham (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen

RecruitingPhase 3
  • Research Site, Durham
Ages 18 and older · All sexes · Updated Oct 30, 2026 · NCT05624450

Women s Health Awareness Community Resiliency, Environmental Action and Collaborations for Health (REACH)

RecruitingObservational studyHealthy volunteers welcome
  • NIEHS Clinical Research Unit (CRU), Research Triangle Park · 7 mi away
Ages 18 to 100 · Women · Updated Oct 23, 2026 · NCT04983251

A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised

RecruitingPhase 3
  • Duke Vaccine and Trials Unit, Durham
  • Duke Vaccine and Trials Unit, Durham
  • Duke University - Main Hospital and Clinics, Durham
Ages 18 and older · All sexes · Updated Oct 14, 2026 · NCT07013474

Long-Term Study of COVID-19 Infection and Long COVID

RecruitingObservational study
  • University of North Carolina, Chapel Hill · 10 mi away
Ages 18 to 75 · All sexes · Updated Sep 28, 2026 · NCT07781501

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

RecruitingObservational studyHealthy volunteers welcome
  • Duke University Health System, Durham
Ages 0 to 20 · All sexes · Updated Aug 21, 2026 · NCT04278404

A Study to Learn About a COVID-19 Vaccine in Healthy Adults 18 Through 64 Years of Age

RecruitingPhase 4Healthy volunteers welcome
  • Duke Vaccine and Trials Unit, Durham
Ages 18 to 64 · All sexes · Updated Aug 7, 2026 · NCT07730450

Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study

RecruitingPhase 3
  • Duke University, Durham
All ages · All sexes · Updated Jun 23, 2026 · NCT03808922

REmotely Monitored, Mobile Health Supported Multidomain Rehabilitation Program With High Intensity Interval Training for COVID-19

Recruiting
  • Duke University Health System, Durham
Ages 18 and older · All sexes · Updated May 28, 2026 · NCT05218083

About Long COVID

Anyone who has had COVID-19 can have long-lasting symptoms, know as long COVID. Learn about the symptoms and how to manage them, diagnosis, and prevention.

More about Long COVID on MedlinePlus

Long COVID trials in other cities

Other studies in Durham

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.