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Major Depressive Disorder clinical trials in Glendale, CA

12 studies for Major Depressive Disorder are looking for participants at sites in and around Glendale (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms

RecruitingPhase 3
  • Behavioral Research Specialists LLC, Glendale
Ages 18 to 74 · All sexes · Updated Sep 25, 2026 · NCT06559306

A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder

RecruitingPhase 3
  • Behavioral Research Specialists, LLC, Glendale
Ages 18 to 85 · All sexes · Updated Sep 25, 2026 · NCT06793397

A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)

RecruitingPhase 2
  • Seaport Investigator Site, Glendale
Ages 18 to 65 · All sexes · Updated Sep 14, 2026 · NCT07065240

ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response

RecruitingPhase 2
  • Behavioral Research Specialists, LLC, Glendale
Ages 18 to 65 · All sexes · Updated Sep 14, 2026 · NCT07284667

A Study of Seltorexant as Monotherapy in Adults and Elderly Participants With Major Depressive Disorder

RecruitingPhase 3
  • Behavioral Research Specialists LLC, Glendale
Ages 18 to 74 · All sexes · Updated Aug 28, 2026 · NCT07573176

NBI-1065845-MDD3025: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

RecruitingPhase 3
  • Neurocrine Clinical Site, Glendale
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT06911112

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder

RecruitingPhase 3
  • Behavioral Research Specialists, Llc, Glendale
Ages 18 to 74 · All sexes · Updated Aug 3, 2026 · NCT06775379

Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

RecruitingPhase 3
  • Neurocrine Clinical Site, Glendale
Ages 18 and older · All sexes · Updated Jul 24, 2026 · NCT06966401

Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol

RecruitingPhase 3
  • Clinical Research Site, Glendale
Ages 18 to 65 · All sexes · Updated Jul 24, 2026 · NCT07484217

A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

RecruitingPhase 2
  • Behavioral Research Specialists, LLC, Glendale
Ages 18 to 65 · All sexes · Updated May 11, 2026 · NCT06524830

Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY)

RecruitingPhase 2
  • Autobahn Site #124, Glendale
Ages 18 to 65 · All sexes · Updated Jan 20, 2026 · NCT06633016

Study of ALTO-300 in MDD

RecruitingPhase 2
  • Site 217, Glendale
Ages 18 to 70 · All sexes · Updated Jul 24, 2025 · NCT05922878

Major Depressive Disorder trials in other cities

Other studies in Glendale

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.