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Major Depressive Disorder clinical trials in New Haven, CT

6 studies for Major Depressive Disorder are looking for participants at sites in and around New Haven (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder

RecruitingPhase 3
  • Yale School of Medicine - Yale Program for Psychedelic Science, New Haven
Ages 18 to 85 · All sexes · Updated Sep 25, 2026 · NCT06793397

A Study of Brenipatide in Adult Participants With Major Depressive Disorder

RecruitingPhase 3
  • Yale University School of Medicine, New Haven
Ages 18 to 75 · All sexes · Updated Aug 6, 2026 · NCT07412756

A Study to Evaluate the Maintenance Effect of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

RecruitingPhase 3
  • Neurocrine Clinical Site, New Haven
Ages 18 and older · All sexes · Updated Jul 24, 2026 · NCT07196501

The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal Effects

RecruitingPhase 2
  • VA Connecticut Healthcare System, West Haven · 3 mi away
Ages 21 to 65 · All sexes · Updated May 6, 2026 · NCT05786066

Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response

RecruitingPhase 1
  • Yale University, New Haven
Ages 18 to 60 · All sexes · Updated May 6, 2026 · NCT05915013

Imaging Depression in Parkinson's Disease

RecruitingPhase 2Healthy volunteers welcome
  • Yale University, New Haven
Ages 40 to 80 · All sexes · Updated Mar 10, 2026 · NCT06402955

Major Depressive Disorder trials in other cities

Other studies in New Haven

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.