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Melanoma clinical trials in Rochester, MN

16 studies for Melanoma are looking for participants at sites in and around Rochester (within about 30 miles). Open a study to see who can join and how to contact the study team.

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

RecruitingPhase 2
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05136196

Pan-tumor MRD Study

RecruitingObservational study
  • Mayo Clinic, Rochester
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06605404

A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

RecruitingPhase 2
  • Local Institution - 0129, Rochester
  • Local Institution - 0174, Rochester
  • Local Institution - 0181, Rochester
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07492680

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

RecruitingObservational study
  • Mayo Clinic (Rochester), Rochester
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444

A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors

RecruitingPhase 1
  • Mayo Clinic - Rochester, Rochester
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT04913285

Project: Every Child for Younger Patients With Cancer

RecruitingObservational study
  • Mayo Clinic in Rochester, Rochester
Up to age 25 · All sexes · Updated Aug 25, 2026 · NCT02402244

Digital Remote Monitoring of Immune Checkpoint Inhibitor Therapy Induced Toxicity Using the Vigilant App

RecruitingObservational study
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT06675643

Evaluation of Anti-PD-1 Therapy by Monitoring T Cell Responses in Melanoma, Lung and Other Cancer Types

RecruitingObservational study
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · All sexes · Updated Jun 18, 2026 · NCT06075524

MC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced Melanoma

RecruitingPhase 1/2
  • Mayo Clinic Rochester, Rochester
Ages 18 to 90 · All sexes · Updated Jun 10, 2026 · NCT05655312

Neoadjuvant Darovasertib in Primary Uveal Melanoma

RecruitingPhase 3
  • Mayo Clinic - PPDS, Rochester
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT07015190

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Mayo Clinic, Rochester
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

RecruitingPhase 3
  • Mayo Clinic Minnesota, Rochester
Ages 18 and older · All sexes · Updated Feb 25, 2026 · NCT05549297

Efficacy of Daromun Neoadjuvant Intratumoral Treatment in Clinical Stage IIIB/C/D Melanoma Patients

RecruitingPhase 3
  • Mayo Clinic, Rochester
Ages 18 and older · All sexes · Updated Dec 17, 2025 · NCT03567889

About Melanoma

Melanoma is the most serious type of skin cancer. Most have a black or black-blue area. Learn the 'ABCDE' of what to watch for and treatment options.

More about Melanoma on MedlinePlus

Melanoma trials in other cities

Other studies in Rochester

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.