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Multiple Myeloma clinical trials in Philadelphia, PA

16 studies for Multiple Myeloma are looking for participants at sites in and around Philadelphia (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in Participants With Previously Treated Multiple Myeloma

RecruitingPhase 3
  • Perelman Center for Advanced Medicine, Philadelphia
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT07555938

A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel

RecruitingPhase 4
  • University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT05201781

A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma or Previously Treated Amyloid Light-chain (AL) Amyloidosis

RecruitingPhase 1
  • University of Pennsylvania Division of Hematology Oncology Perelman Center for Advanced Medicine, Philadelphia
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT05652335

A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma

RecruitingPhase 3
  • Thomas Jefferson University Hospital, Philadelphia
  • Fox Chase Cancer Center, Philadelphia
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07258511

AZD0305 as Monotherapy or in Combination With Anticancer Agents in Participants With Multiple Myeloma

RecruitingPhase 1/2
  • Research Site, Philadelphia
Ages 18 and older · All sexes · Updated Oct 30, 2026 · NCT06106945

A Study of an MMSET Inhibitor in Patients With Relapsed and Refractory Multiple Myeloma

RecruitingPhase 1
  • University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Oct 22, 2026 · NCT05651932

A Phase III, Multicentre Study to Evaluate Consolidation Treatment With AZD0120 Compared With ASCT, in Participants With Newly Diagnosed Multiple Myeloma Who Are Transplant Eligible (DURGA-6).

RecruitingPhase 3
  • Research Site, Philadelphia
  • Research Site, Philadelphia
Ages 18 to 130 · All sexes · Updated Oct 21, 2026 · NCT07735637

Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma

RecruitingPhase 2
  • Sidney Kimmel Cancer Center - Jefferson Health, Philadelphia
Ages 18 and older · All sexes · Updated Oct 6, 2026 · NCT06297226

Limited-duration Teclistamab

RecruitingPhase 2
  • Abramson Cancer Center at University of Pennsylvania, Philadelphia
  • Thomas Jefferson University, Honickman Center, Philadelphia
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT05932680

A Study of mRNA-2808 in Participants With Relapsed or Refractory Multiple Myeloma

RecruitingPhase 1/2
  • Penn Medicine, Philadelphia
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07116616

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

RecruitingPhase 2
  • Fox Chase Cancer Center, Philadelphia
Ages 12 and older · All sexes · Updated Sep 22, 2026 · NCT02693535

Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

RecruitingPhase 3
  • Thomas Jefferson University Hospital, Philadelphia
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT04566328

Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies

RecruitingPhase 1/2
  • Penn Medicine - Abramson Cancer Center Perelman, Philadelphia
Ages 18 and older · All sexes · Updated Jun 24, 2026 · NCT04068597

Low-Dose Radiotherapy in Treating Painful Bone Metastases in Patients With Multiple Myeloma

Recruiting
  • University of Pennsylvania/Abramson Cancer Center, Philadelphia
Ages 18 and older · All sexes · Updated Jun 5, 2026 · NCT03858205

A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)

RecruitingPhase 1/2
  • Sidney Kimmel Comprehensive Cancer Center, Philadelphia
Ages 12 and older · All sexes · Updated Mar 24, 2026 · NCT04988555

Mozobil for Autologous Hematopoietic Stem Cell Transplantation

RecruitingPhase 2
  • Thomas Jefferson University Hospital, Philadelphia
Ages 18 and older · All sexes · Updated Nov 28, 2025 · NCT07188090

About Multiple Myeloma

Multiple myeloma is a cancer that begins in plasma cells, a type of white blood cell. Discover symptoms, diagnostic tests, and treatments for myeloma.

More about Multiple Myeloma on MedlinePlus

Multiple Myeloma trials in other cities

Other studies in Philadelphia

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.