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Obesity clinical trials in Missouri

53 studies for Obesity are looking for participants at sites in Missouri.

Cities in Missouri

A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide

  • Amicis Centers of Clinical Research, St Louis
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 28, 2026 ยท NCT07668414

AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose Weight

  • StudyMetrix Research LLC, City of Saint Peters
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 28, 2026 ยท NCT07720271

Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities

  • Studymetrix Research /ID# 282163, City of Saint Peters
RecruitingPhase 2
Ages 18 to 75 ยท All sexes ยท Updated Sep 25, 2026 ยท NCT07752979

AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight

  • StudyMetrix Research LLC, City of Saint Peters
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 24, 2026 ยท NCT07339423

A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

  • Sundance Clinical Research, St Louis
RecruitingPhase 3
Ages 6 to 17 ยท All sexes ยท Updated Sep 24, 2026 ยท NCT06672549

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

  • Washington University School of Medicine, St Louis
RecruitingPhase 3
Ages 18 to 70 ยท All sexes ยท Updated Sep 24, 2026 ยท NCT06937099

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

  • Washington University School of Medicine, St Louis
RecruitingPhase 3
Ages 18 to 70 ยท All sexes ยท Updated Sep 24, 2026 ยท NCT06937086

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

  • StudyMetrix Research, City of Saint Peters
  • Alliance for Multispecialty Research - Kansas City, Kansas City
  • Kansas City Veterans Affairs Medical Center, Kansas City
  • and 1 more
RecruitingPhase 3
Ages 45 to 99 ยท All sexes ยท Updated Sep 22, 2026 ยท NCT07037433

A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight

  • Research Site, Kansas City
  • Research Site, Kansas City
  • Research Site, St Louis
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 22, 2026 ยท NCT07784270

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes

  • Clinical Research Professionals, Chesterfield
  • Clinvest Headlands Llc, Springfield
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 22, 2026 ยท NCT07282600

A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight

  • Clayton Sleep Institute - St. Louis - Tesson Ferry Road, St Louis
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 22, 2026 ยท NCT07369011

A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin

  • Clinical Research Professionals, Chesterfield
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 22, 2026 ยท NCT07392190

A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight

  • StudyMetrix Research, City of Saint Peters
  • Clinvest Headlands Llc, Springfield
RecruitingPhase 2
Ages 18 to 75 ยท All sexes ยท Updated Sep 22, 2026 ยท NCT07589608

A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the Knee

  • StudyMetrix Research, City of Saint Peters
  • AMR Clinical, Kansas City
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 22, 2026 ยท NCT07153471

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes

  • AURORA-2 Clinical Site, Columbia
  • AURORA-2 Clinical Site, St Louis
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 16, 2026 ยท NCT07743450

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities

  • AURORA-1 Clinical Site, St Louis
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 16, 2026 ยท NCT07743463

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

  • Saint Luke's Hospital of Kansas City, Kansas City
RecruitingPhase 3
Ages 18 to 99 ยท All sexes ยท Updated Sep 16, 2026 ยท NCT07037459

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes

  • Clinvest Research LLC, Springfield
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 14, 2026 ยท NCT07351045

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes

  • Kansas City VA Medical Center, Kansas City
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 14, 2026 ยท NCT07351058

First-in-human Study of the Safety, Tolerability, Pharmacokinetics, and Food Effect of ACCG-2671

  • Research Site, Springfield
RecruitingPhase 1/2Healthy volunteers welcome
Ages 25 to 75 ยท All sexes ยท Updated Sep 14, 2026 ยท NCT07815678

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

  • ACCOMPLISH-2 Research Site, Chesterfield
  • ACCOMPLISH-2 Research Site, City of Saint Peters
  • ACCOMPLISH-2 Research Site, Hazelwood
  • and 2 more
RecruitingPhase 3Healthy volunteers welcome
Ages 18 to 79 ยท All sexes ยท Updated Sep 11, 2026 ยท NCT07654374

Research Study on How Well Oral Semaglutide Works for Weight Loss in Adults With Excess Body Weight

  • StudyMetrix Research LLC, City of Saint Peters
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 9, 2026 ยท NCT07770841

A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight

  • StudyMetrix Research, City of Saint Peters
  • Clinvest Headlands Llc, Springfield
RecruitingPhase 2
Ages 18 to 75 ยท All sexes ยท Updated Sep 8, 2026 ยท NCT06143956

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)

  • Alliance for Multispecialty Research - Kansas City, Kansas City
RecruitingPhase 3
Ages 18 to 99 ยท All sexes ยท Updated Sep 3, 2026 ยท NCT07684235

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)

  • Alliance for Multispecialty Research - Kansas City, Kansas City
RecruitingPhase 3
Ages 18 to 99 ยท All sexes ยท Updated Sep 3, 2026 ยท NCT07684144

A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus

  • Research Site, Jefferson City
  • Research Site, Kansas City
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Aug 25, 2026 ยท NCT07784725

Digital InteGrated Behavioral treatmeNt for Comorbid obesITy and deprEssion Among Racial and Ethnic Adults Age 50 and Older

  • Washington University School of Medicine in St Louis, St Louis
Recruiting
Ages 50 to 74 ยท All sexes ยท Updated Aug 18, 2026 ยท NCT06636058

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

  • Clinical Research Consultants, JCCT Co, Kansas City
  • Washington University, St Louis
  • Amicis Centers of Clinical Research, St Louis
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Aug 18, 2026 ยท NCT07567001

AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain

  • Clinvest Research, Springfield
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Aug 17, 2026 ยท NCT07509307

Role of KATP Channel Loss in Type 2 Diabetes

  • Washington University in St. Louis, St Louis
RecruitingHealthy volunteers welcome
Ages 18 to 65 ยท All sexes ยท Updated Aug 10, 2026 ยท NCT06830096

Advancing Biopsychosocial Care Training Initiative

  • Washington University School of Medicine, St Louis
RecruitingHealthy volunteers welcome
Ages 5 and older ยท All sexes ยท Updated Aug 10, 2026 ยท NCT07049861

Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)

  • ACCOMPLISH-1 Research Site, Chesterfield
  • ACCOMPLISH-1 Research Site, Hazelwood
  • ACCOMPLISH-1 Research Site, St Louis
RecruitingPhase 3
Ages 18 to 79 ยท All sexes ยท Updated Aug 10, 2026 ยท NCT07654361

Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity

  • University of Missouri School of Medicine, Columbia
RecruitingHealthy volunteers welcome
Ages 18 to 70 ยท All sexes ยท Updated Aug 6, 2026 ยท NCT06335771

Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity (ATM)

  • University of Missouri School of Medicine, Columbia
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 70 ยท All sexes ยท Updated Aug 6, 2026 ยท NCT06571474

Routine Validation and Reproducibility Testing of Laboratory Measures and Research Techniques Used for Metabolism Research (VAL)

  • University of Missouri School of Medicine, Columbia
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 75 ยท All sexes ยท Updated Aug 4, 2026 ยท NCT06286761

Effects of Grape Consumption on the Immune-Gut Axis in Obesity

  • University of Missouri-Columbia, Columbia
Recruiting
Ages 18 to 60 ยท All sexes ยท Updated Jul 31, 2026 ยท NCT07231484

Sex Disparities in Hypoxic Vasodilation and Impact of Obesity

  • University of Missouri, Columbia
RecruitingEarly phase 1Healthy volunteers welcome
Ages 18 to 45 ยท All sexes ยท Updated Jul 28, 2026 ยท NCT05219799

Evaluation of a Novel Technology to Support Tailored Health Behavior Counseling in Rural Primary Care Clinics

  • Washington University in St. Louis, St Louis
Recruiting
Ages 18 to 64 ยท All sexes ยท Updated Jul 17, 2026 ยท NCT06397729

Small Extracellular Vesicles and Insulin Action

  • Washington University School of Medicine, St Louis
RecruitingHealthy volunteers welcome
Ages 25 to 55 ยท All sexes ยท Updated Jul 17, 2026 ยท NCT05933707

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.