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Overweight clinical trials in Missouri

32 studies for Overweight are looking for participants at sites in Missouri.

Cities in Missouri

A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide

  • Amicis Centers of Clinical Research, St Louis
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07668414

A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity

  • Clinvest Headlands Llc, Springfield
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07794579

AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose Weight

  • StudyMetrix Research LLC, City of Saint Peters
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07720271

Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities

  • Studymetrix Research /ID# 282163, City of Saint Peters
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 25, 2026 · NCT07752979

A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

  • Sundance Clinical Research, St Louis
RecruitingPhase 3
Ages 6 to 17 · All sexes · Updated Sep 24, 2026 · NCT06672549

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

  • Washington University School of Medicine, St Louis
RecruitingPhase 3
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937099

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

  • Washington University School of Medicine, St Louis
RecruitingPhase 3
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937086

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

  • StudyMetrix Research, City of Saint Peters
  • Alliance for Multispecialty Research - Kansas City, Kansas City
  • Kansas City Veterans Affairs Medical Center, Kansas City
  • and 1 more
RecruitingPhase 3
Ages 45 to 99 · All sexes · Updated Sep 22, 2026 · NCT07037433

A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight

  • Research Site, Kansas City
  • Research Site, Kansas City
  • Research Site, St Louis
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07784270

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes

  • Clinical Research Professionals, Chesterfield
  • Clinvest Headlands Llc, Springfield
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07282600

A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight

  • Clayton Sleep Institute - St. Louis - Tesson Ferry Road, St Louis
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07369011

A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin

  • Clinical Research Professionals, Chesterfield
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07392190

A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight

  • StudyMetrix Research, City of Saint Peters
  • Clinvest Headlands Llc, Springfield
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 22, 2026 · NCT07589608

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes

  • AURORA-2 Clinical Site, Columbia
  • AURORA-2 Clinical Site, St Louis
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07743450

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities

  • AURORA-1 Clinical Site, St Louis
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07743463

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes

  • Clinvest Research LLC, Springfield
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07351045

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes

  • Kansas City VA Medical Center, Kansas City
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07351058

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

  • ACCOMPLISH-2 Research Site, Chesterfield
  • ACCOMPLISH-2 Research Site, City of Saint Peters
  • ACCOMPLISH-2 Research Site, Hazelwood
  • and 2 more
RecruitingPhase 3Healthy volunteers welcome
Ages 18 to 79 · All sexes · Updated Sep 11, 2026 · NCT07654374

Research Study on How Well Oral Semaglutide Works for Weight Loss in Adults With Excess Body Weight

  • StudyMetrix Research LLC, City of Saint Peters
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07770841

A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight

  • StudyMetrix Research, City of Saint Peters
  • Clinvest Headlands Llc, Springfield
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 8, 2026 · NCT06143956

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)

  • Alliance for Multispecialty Research - Kansas City, Kansas City
RecruitingPhase 3
Ages 18 to 99 · All sexes · Updated Sep 3, 2026 · NCT07684235

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)

  • Alliance for Multispecialty Research - Kansas City, Kansas City
RecruitingPhase 3
Ages 18 to 99 · All sexes · Updated Sep 3, 2026 · NCT07684144

A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus

  • Research Site, Jefferson City
  • Research Site, Kansas City
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT07784725

AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain

  • Clinvest Research, Springfield
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT07509307

Advancing Biopsychosocial Care Training Initiative

  • Washington University School of Medicine, St Louis
RecruitingHealthy volunteers welcome
Ages 5 and older · All sexes · Updated Aug 10, 2026 · NCT07049861

Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)

  • ACCOMPLISH-1 Research Site, Chesterfield
  • ACCOMPLISH-1 Research Site, Hazelwood
  • ACCOMPLISH-1 Research Site, St Louis
RecruitingPhase 3
Ages 18 to 79 · All sexes · Updated Aug 10, 2026 · NCT07654361

Effects of Grape Consumption on the Immune-Gut Axis in Obesity

  • University of Missouri-Columbia, Columbia
Recruiting
Ages 18 to 60 · All sexes · Updated Jul 31, 2026 · NCT07231484

Effect of Ketone Esters on Liver Fat Content and Metabolic Function

  • Washington University School of Medicine, St Louis
RecruitingPhase 2Healthy volunteers welcome
Ages 18 to 40 · All sexes · Updated Jul 15, 2026 · NCT07097506

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MBX 4291 in Adult Participants With Obesity

  • MBX Biosciences Investigational Site, Kansas City
RecruitingPhase 1
Ages 18 to 65 · All sexes · Updated Jun 9, 2026 · NCT07142707

Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)

  • Washington University School of Medicine, St Louis
RecruitingObservational studyHealthy volunteers welcome
Ages 12 to 17 · All sexes · Updated Dec 18, 2025 · NCT05277558

Social Determinants and a Diabetes Prevention Program Tailored for African Americans

  • University Health, Kansas City
  • University of Missouri-Kansas City, Kansas City
RecruitingPhase 2Healthy volunteers welcome
Ages 18 and older · All sexes · Updated May 25, 2025 · NCT05301413

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.