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Type 2 Diabetes clinical trials in Houston, TX

30 studies for Type 2 Diabetes are looking for participants at sites in and around Houston (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity

RecruitingPhase 3
  • PlanIt Research, LLC (Monitoring Room), Houston
  • PlanIt Research, LLC, Houston
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07595549

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

RecruitingHealthy volunteers welcome
  • Helium Research Group, Houston
  • Kelsey Research Foundation, Houston
  • The Methodist Hospital, DeBakey Cardiology Associates, Houston
  • and 1 more
Ages 55 and older · All sexes · Updated Sep 28, 2026 · NCT06112418

A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event

RecruitingPhase 2
  • Cardiovascular Specialists of Willowbrook, Houston
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07783802

A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight

RecruitingPhase 3
  • Research Site, Houston
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07784270

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes

RecruitingPhase 3
  • Juno Research, Houston
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07282600

A Study to Test Whether Survodutide Helps People With Type 2 Diabetes Control Their Blood Sugar

RecruitingPhase 3
  • Juno Research, LLC, Houston
  • Biopharma Informatic, Inc. Research Center, Houston
  • Research Physicians Network, Houston
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07754461

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes

RecruitingPhase 3
  • AURORA-2 Clinical Site, Houston
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07743450

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

RecruitingPhase 3
  • Victorium Clinical Research, Houston
  • Houston Research Institute, Houston
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07064473

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes

RecruitingPhase 3
  • HRI ? Medical Center, LLC, Houston
  • Juno Research, LLC, Houston
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07351058

A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide

RecruitingPhase 2
  • Juno Research, Houston
Ages 18 to 75 · All sexes · Updated Sep 14, 2026 · NCT06897475

A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes

RecruitingPhase 2
  • JCCT- Juno NW Houston, Houston
Ages 18 to 75 · All sexes · Updated Sep 11, 2026 · NCT07415954

Study to Assess the Effects of ALN-ANG3 in Adult Participants With Diabetic Kidney Disease

RecruitingPhase 2
  • Juno Research, LLC, Houston
  • Prolato Research LLC, Houston
  • Clinical Trial Network, LLC, Houston
Ages 18 to 80 · All sexes · Updated Sep 11, 2026 · NCT07271186

A Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 Diabetes

RecruitingPhase 2
  • Private Practice - Dr. Laila A. Hassan, Houston
Ages 18 to 75 · All sexes · Updated Sep 11, 2026 · NCT07668388

A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus

RecruitingPhase 3
  • Research Site, Houston
  • Research Site, Houston
  • Research Site, Houston
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07662213

A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes

RecruitingPhase 3
  • Amir Ali Hassan, MD, PA, Houston
Ages 10 to 18 · All sexes · Updated Sep 9, 2026 · NCT07282613

Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)

RecruitingPhase 2
  • Juno Research, LLC, Houston
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07296484

A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 Diabetes

RecruitingPhase 2
  • Biopharma Informatic, LLC, Houston
  • PlanIt Research, PLLC, Houston
  • Research Physicians Network, LLC, Houston
Ages 18 to 75 · All sexes · Updated Sep 8, 2026 · NCT07215559

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)

RecruitingPhase 3
  • JCCT- Juno Northwest Houston, Houston
  • Johnson County Clinical Trials Juno Bellaire, Bellaire · 7 mi away
Ages 18 to 99 · All sexes · Updated Sep 3, 2026 · NCT07684144

AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and Blood Vessels Treated With 1-3 Other Diabetes Medications

RecruitingPhase 3
  • PrimeCare Medical Group, Houston
  • JCCT- Juno NW Houston, Houston
  • Biopharma Informatic_Houston, Houston
  • and 2 more
Ages 45 and older · All sexes · Updated Sep 1, 2026 · NCT07797335

A Study of Dulaglutide (LY2189265) 3.0 mg and 4.5 mg in Pediatric Participants With Type 2 Diabetes Mellitus (AWARD-PEDS PLUS)

RecruitingPhase 3
  • Texas Childrens Hospital, Houston
  • UT Health Houston, Houston
Ages 10 to 17 · All sexes · Updated Aug 7, 2026 · NCT06739122

A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus on Background Insulin

RecruitingPhase 3
  • Research Site, Houston
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT07664553

Efficacy of the Omnipod® 6 System Compared With the Omnipod® 5 System

Recruiting
  • Baylor College of Medicine, Houston
Ages 14 to 75 · All sexes · Updated Aug 3, 2026 · NCT07579702

Adapting and Assessing the Feasibility of a Telehealth Diabetes Prevention Program for Hispanic Adolescents

RecruitingHealthy volunteers welcomeMentions payment for participants
  • USDA/ARS Children's Nutrition Research Center, Baylor College of Medicine, Houston
Ages 14 to 16 · All sexes · Updated Jul 7, 2026 · NCT06943001

CGM for Management of Type 2 Diabetes in Pregnancy

Recruiting
  • University of Texas Health Science Center at Houston, Houston
Ages 18 to 50 · Women · Updated Jun 29, 2026 · NCT06628453

Implementation pRogram to Improve Screening and Management for CKD in Diabetes (IRIS-CKD) (Program 2)

Recruiting
  • Houston Methodist, Houston
Ages 18 and older · All sexes · Updated Jun 16, 2026 · NCT06906640

Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Mellitus Who Are Not Achieving Glycemic Targets While Using GLP-1-Based Therapy

RecruitingPhase 2
  • Synergy Group Medical, Houston
Ages 18 to 70 · All sexes · Updated Jun 15, 2026 · NCT07502508

DISCOVERY of Risk Factors for Type 2 Diabetes in Youth

RecruitingObservational study
  • Baylor College of Medicine / Texas Children's, Houston
Ages 8 to 15 · All sexes · Updated May 7, 2026 · NCT06525259

Determinants of Insulin Sensitivity by Age, Sex, Race/Ethnicity, BMI, and PCOS Diagnosis

RecruitingObservational studyHealthy volunteers welcome
  • Lilli Health, Houston
Ages 18 and older · All sexes · Updated May 1, 2026 · NCT05950282

RESET System Pivotal Trial (Rev F)

Recruiting
  • Baylor College of Medicine, Houston
Ages 22 to 65 · All sexes · Updated Jul 18, 2024 · NCT04101669

About Type 2 Diabetes

Type 2 Diabetes, previously referred to as Adult Onset Diabetes, is the more common type. Risk factors include obesity and family history.

More about Type 2 Diabetes on MedlinePlus

Type 2 Diabetes trials in other cities

Other studies in Houston

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.