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Glioblastoma clinical trials in Pittsburgh, PA

9 studies for Glioblastoma are looking for participants at sites in and around Pittsburgh (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Testing the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors That Have Returned After Previous Treatment

RecruitingPhase 1/2
  • UPMC Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05432804

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

RecruitingPhase 2/3
  • University of Pittsburgh Medical Center - Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT03970447

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

RecruitingPhase 2
  • UPMC Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07326566

Beginning Radiation Immediately With GammaTile at GBM Excision Versus Standard of Care

RecruitingPhase 3
  • Allegheny Health Network, Pittsburgh
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07195591

Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma

RecruitingPhase 1
  • UPMC Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06860594

SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

RecruitingPhase 3
  • UPMC Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT05303519

INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)

RecruitingPhase 2
  • University of Pittsburgh Medical Center, Pittsburgh
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT02977780

DOC1021 Dendritic Cell Immunotherapy for Treatment of Newly Diagnosed Adult Glioblastoma (GBM)

RecruitingPhase 2
  • UPMC Presbyterian Hospital, Pittsburgh
Ages 18 and older · All sexes · Updated Jul 1, 2026 · NCT06805305

Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors

RecruitingPhase 1
  • University of Pittsburg Medical Center (UPCM), Pittsburgh
Ages 18 and older · All sexes · Updated Jun 11, 2026 · NCT05283330

Glioblastoma trials in other cities

Other studies in Pittsburgh

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.