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Acute Myeloid Leukemia clinical trials in St. Louis, MO

22 studies for Acute Myeloid Leukemia are looking for participants at sites in and around St. Louis (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

RecruitingPhase 2
  • Washington University School of Medicine, St Louis
  • Siteman Cancer Center-South County, St Louis
  • Missouri Baptist Medical Center, St Louis
  • and 3 more
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT05564390

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Mercy Infusion Center - Chippewa, St Louis
  • Mercy Hospital South, St Louis
  • Missouri Baptist Medical Center, St Louis
  • and 4 more
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Testing the Anti-cancer Drug, Cirtuvivint, and Its Combination With ASTX727 to Improve Outcomes in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndromes

RecruitingPhase 1
  • Washington University School of Medicine, St Louis
  • Siteman Cancer Center-South County, St Louis
  • Siteman Cancer Center at Christian Hospital, St Louis
  • and 1 more
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06484062

Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

RecruitingPhase 2
  • Washington University School of Medicine, St Louis
  • Siteman Cancer Center-South County, St Louis
  • Siteman Cancer Center at Christian Hospital, St Louis
  • and 2 more
Ages 18 to 59 · All sexes · Updated Sep 28, 2026 · NCT05554393

A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)

RecruitingPhase 3
  • Washington University in St Louis, St Louis
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06852222

Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)

RecruitingPhase 2
  • Washington University School of Medicine, St Louis
  • Siteman Cancer Center-South County, St Louis
  • Siteman Cancer Center at Christian Hospital, St Louis
  • and 2 more
Ages 18 to 59 · All sexes · Updated Sep 22, 2026 · NCT05554406

Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

RecruitingPhase 2
  • Washington University School of Medicine, St Louis
  • Siteman Cancer Center-South County, St Louis
  • Siteman Cancer Center at Christian Hospital, St Louis
  • and 3 more
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06317649

A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

RecruitingPhase 3
  • Washington University School of Medicine, St Louis
  • Mercy Hospital Saint Louis, St Louis
6 Months – 21 Years · All sexes · Updated Sep 17, 2026 · NCT04293562

A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

RecruitingPhase 1/2
  • Washington University in St. Louis School of Medicine, St Louis
30 Days · All sexes · Updated Sep 16, 2026 · NCT04065399

A Longitudinal Multi-Center Molecular Biomarker Discovery Registry for Patients With Hematologic Malignancies

RecruitingObservational study
  • Washington University in St. Louis, St Louis
Ages 0 and older · All sexes · Updated Sep 2, 2026 · NCT07154823

Bleximenib in Combination With Standard Induction and Consolidation Therapy Followed by Maintenance for Treatment of Patients With Acute Myeloid Leukemia (AML)

RecruitingPhase 3
  • US-St Louis MO-WASHU, St Louis
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT07223814

Eganelisib as Monotherapy and in Combination With Cytarabine in Relapsed/Refractory AML

RecruitingPhase 1
  • Washington University in St Louis, St Louis
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT06533761

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

RecruitingPhase 1/2
  • Cardinal Glennon Children's Medical Center, St Louis
  • Washington University School of Medicine, St Louis
  • Mercy Hospital Saint Louis, St Louis
Up to age 22 · All sexes · Updated Aug 25, 2026 · NCT04726241

Pilot Study of Memory-like Natural Killer (ML NK) Cells After TCRαβ T Cell Depleted Haploidentical Transplant in AML

RecruitingPhase 1/2
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06158828

Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)

RecruitingPhase 3
  • Washington University School of Medicine in St. Louis, St Louis
29 Days – 21 Years · All sexes · Updated Aug 24, 2026 · NCT05183035

Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia

RecruitingPhase 1
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT06001788

Motixafortide for MRD Sensitization in AML

RecruitingPhase 2
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated Jul 24, 2026 · NCT07392970

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

RecruitingObservational study
  • Cardinal Glennon Children's Medical Center, St Louis
  • Washington University St. Louis, St Louis
  • Washington University/St. Louis Children's Hospital, St Louis
All ages · All sexes · Updated Jul 6, 2026 · NCT01351545

A Study of CBX-250 in Participants With Relapsed or Refractory Myeloid Leukemias

RecruitingPhase 1
  • Washington University in St. Louis, St Louis
Ages 12 and older · All sexes · Updated Mar 16, 2026 · NCT06994676

Whole Genome Sequencing (ChromoSeq) as an Adjunct to Conventional Genomic Profiling in AML and MDS

RecruitingHealthy volunteers welcome
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated Oct 16, 2025 · NCT04986657

About Acute Myeloid Leukemia

Acute Myeloid Leukemia (AML) is a cancer of the white blood cells. AML usually gets worse quickly if it is not treated. Read more.

More about Acute Myeloid Leukemia on MedlinePlus

Acute Myeloid Leukemia trials in other cities

Other studies in St. Louis

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.