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Colorectal Cancer clinical trials in Ann Arbor, MI

23 studies for Colorectal Cancer are looking for participants at sites in and around Ann Arbor (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Colonoscopy vs Stool Testing for Older Adults With Colon Polyps

Recruiting
  • University of Michigan Health, Ann Arbor
Ages 65 to 82 · All sexes · Updated Oct 2, 2026 · NCT05612347

Family Communications After Genetic Testing

RecruitingHealthy volunteers welcome
  • Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor
  • Huron Gastroenterology PC, Ypsilanti · 7 mi away
  • Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti · 7 mi away
  • and 4 more
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07143487

Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial

RecruitingPhase 2
  • Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor
  • Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti · 7 mi away
  • Chelsea Hospital, Chelsea · 15 mi away
  • and 3 more
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT05673148

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor
  • Huron Gastroenterology PC, Ypsilanti · 7 mi away
  • Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti · 7 mi away
  • and 4 more
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

RecruitingPhase 3
  • University of Michigan Rogel Cancer Center, Ann Arbor
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06750094

A Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants With Advanced or Metastatic Colorectal Cancer

RecruitingPhase 1/2
  • University of Michigan Health System, Ann Arbor
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05379595

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

RecruitingPhase 3
  • VA Ann Arbor Healthcare System, Ann Arbor
  • University of Michigan, Ann Arbor
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06662786

A Study to Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of VVD-133214 as Monotherapy and in Combination in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • University of Michigan, Ann Arbor
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06004245

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

RecruitingPhase 3
  • University of Michigan Rogel Cancer Center, Ann Arbor
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT05863195

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

RecruitingPhase 1/2
  • University of Michigan Medical School Rogel Cancer Center, Ann Arbor
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07629960

A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

RecruitingPhase 3
  • Trinity Health St Joseph Mercy Ann Arbor, Ann Arbor
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07284849

Testing for Safety and Colorectal Cancer Preventive Effects of ONC201

RecruitingPhase 1
  • University of Michigan Rogel Cancer Center, Ann Arbor
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT05630794

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

RecruitingPhase 1/2
  • C S Mott Children's Hospital, Ann Arbor
12 Months – 30 Years · All sexes · Updated Aug 25, 2026 · NCT04851119

A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

RecruitingPhase 1/2
  • University of Michigan, Ann Arbor
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT07020221

FITting Non-invasive Tests in Lynch Syndrome Surveillance

RecruitingObservational study
  • University of Michigan, Ann Arbor
Ages 20 to 80 · All sexes · Updated Apr 16, 2026 · NCT06898996

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

RecruitingPhase 3Healthy volunteers welcome
  • Trinity Health IHA - Obstetrics and Gynecology West Arbor, Ann Arbor
  • Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor
  • Huron Gastroenterology PC, Ypsilanti · 7 mi away
  • and 5 more
Ages 18 and older · All sexes · Updated Mar 31, 2026 · NCT07018869

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

A Self-Monitoring Platform for Tracking Medication Safety and Concerns in Cancer Patients

Recruiting
  • University of Michigan Comprehensive Cancer Center, Ann Arbor
Ages 18 and older · All sexes · Updated Jan 21, 2026 · NCT07291414

Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer

RecruitingObservational study
  • Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor
  • Trinity Health IHA Medical Group Hematology Oncology -Ann Arbor, Ypsilanti · 7 mi away
  • Chelsea Hospital, Chelsea · 15 mi away
  • and 3 more
Ages 60 and older · All sexes · Updated Jan 8, 2026 · NCT03998202

About Colorectal Cancer

Colorectal cancer starts in the colon or rectum. It may not cause symptoms at first. Screening tests can help find it early, when treatment is most effective.

More about Colorectal Cancer on MedlinePlus

Colorectal Cancer trials in other cities

Other studies in Ann Arbor

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.