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Type 2 Diabetes clinical trials recruiting in the U.S.

240 studies for Type 2 Diabetes are recruiting participants at sites across the United States.

Type 2 Diabetes, previously referred to as Adult Onset Diabetes, is the more common type. Risk factors include obesity and family history.

Cities with the most studies

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Recently updated studies

Glycemic and Weight Loss Effects of GLP-1R Agonist Therapy in Subjects With Spinal Cord Injury and Type 2 Diabetes

RecruitingPhase 4
Ages 18 to 70 · All sexes · Updated Oct 5, 2026 · NCT06706284

Integrating New Skills Into Diabetes Education With CGM

Recruiting
Ages 65 and older · All sexes · Updated Oct 5, 2026 · NCT07463209

SMART 2D: Study of Montelukast's Effects on Renal and Cardiovascular Health in Adolescents and Young Adults With Type 2 Diabetes

RecruitingEarly phase 1
Ages 14 to 24 · All sexes · Updated Oct 5, 2026 · NCT07409714

The RESET System Pivotal Clinical Trial (Protocol Revision H)

Recruiting
Ages 22 to 65 · All sexes · Updated Oct 5, 2026 · NCT04101669

Efficacy of Using Mobile Health Applications for Health

RecruitingHealthy volunteers welcome
Ages 18 to 64 · All sexes · Updated Oct 2, 2026 · NCT05589155

Efficacy of mHealth Apps for Health in a Low-income, Type II Diabetic, Hispanic Population

RecruitingHealthy volunteers welcome
Ages 18 to 64 · All sexes · Updated Oct 2, 2026 · NCT05279729

Hydration Intervention to Decrease Side Effects Associated With GLP - 1 RA Therapy

Recruiting
Ages 18 to 60 · All sexes · Updated Oct 2, 2026 · NCT07641361

Implementation pRogram to Improve Screening and Management for CKD in Diabetes (Program 1) (IRIS-CKD)

Recruiting
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06906627

Implementation pRogram to Improve Screening and Management for CKD in Diabetes (IRIS-CKD) (Program 2)

Recruiting
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06906640

A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07783802

A Study to Test Whether Survodutide Helps People With Type 2 Diabetes Control Their Blood Sugar

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07754461

Research Study on How People With Type 2 Diabetes Tolerate Switching From Semaglutide to Cagrisema

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07817251

A Randomized Controlled Trial of Diabetes Screening Immediately Postpartum (DIP) and Follow Up PP CARE

Recruiting
Ages 18 and older · Women · Updated Sep 29, 2026 · NCT05909046

A Study of PATAS Using Single Ascending Doses in Healthy Volunteers and Multiple Ascending Doses in Diabetic Subjects

RecruitingPhase 1
Ages 18 to 65 · All sexes · Updated Sep 29, 2026 · NCT07223333

A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07595549

Study of ALV-100 to Assess Safety, Tolerability, and PK/PD in Overweight/Obese Participants With or Without T2D

RecruitingPhase 1
Ages 18 to 65 · All sexes · Updated Sep 28, 2026 · NCT07399678

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

RecruitingHealthy volunteers welcome
Ages 55 and older · All sexes · Updated Sep 28, 2026 · NCT06112418

ACCESS 2: AI for pediatriC diabetiC Eye examS Study 2

Recruiting
Ages 8 to 21 · All sexes · Updated Sep 23, 2026 · NCT05463289

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07282600

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.