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Healthy volunteer studies in Portland, OR

66 studies at sites in and around Portland accept healthy volunteers — people without the condition being studied. Many studies pay participants for their time and travel; the amount is set by each study, so ask the study team.

Clinical Outcomes and Pharmacotherapy Effectiveness in the VA Health Care System (COPE-VA)

RecruitingObservational studyHealthy volunteers welcome
  • VA Portland Health Care System, Portland, OR, Portland
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT06160128

Cessation or Reduction of Alcohol Consumption in Veterans: A Randomized Controlled Trial for Alcohol Use Disorder (CRAVE)

RecruitingPhase 3Healthy volunteers welcome
  • VA Portland Health Care System, Portland, OR, Portland
Ages 18 to 80 · All sexes · Updated Sep 21, 2026 · NCT07218354

A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age

RecruitingPhase 3Healthy volunteers welcome
  • GSK Investigational Site, Portland
Ages 65 and older · All sexes · Updated Sep 18, 2026 · NCT07805707

Connect for Cancer Prevention Study (Connect)

RecruitingObservational studyHealthy volunteers welcome
  • Kaiser Permanente Northwest, Portland
Ages 30 to 70 · All sexes · Updated Sep 17, 2026 · NCT04609072

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

RecruitingPhase 3Healthy volunteers welcome
  • ACCOMPLISH-2 Research Site, Portland
Ages 18 to 79 · All sexes · Updated Sep 11, 2026 · NCT07654374

Functional and Structural Imaging for Glaucoma

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health & Science University, Casey Eye Institute, Portland
Ages 40 to 85 · All sexes · Updated Sep 9, 2026 · NCT01957267

A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older

RecruitingPhase 3Healthy volunteers welcome
  • Kaiser Permanente Center for Health Research, Portland
Ages 65 and older · All sexes · Updated Sep 9, 2026 · NCT07282665

Natural History and Biospecimen Acquisition for Children and Adults With Rare Solid Tumors

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health and Science University, Portland
4 Weeks · All sexes · Updated Sep 2, 2026 · NCT03739827

Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer

RecruitingHealthy volunteers welcome
  • Providence Portland Medical Center, Portland
  • Providence Saint Vincent Medical Center, Portland
  • Providence Willamette Falls Medical Center, Oregon City · 12 mi away
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07091617

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Providence Portland Medical Center, Portland
  • Providence Saint Vincent Medical Center, Portland
  • Providence Willamette Falls Medical Center, Oregon City · 12 mi away
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069

Family Communications After Genetic Testing

RecruitingHealthy volunteers welcome
  • Providence Portland Medical Center, Portland
  • Providence Saint Vincent Medical Center, Portland
  • Providence Willamette Falls Medical Center, Oregon City · 12 mi away
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07143487

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

RecruitingPhase 4Healthy volunteers welcome
  • Oregon Health and Science University, Portland
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

An Exercise Intervention for Improving Mental and Physical Health in Patients With Primary Brain Tumors and Their Caregivers, ET-NEURO Trial

RecruitingHealthy volunteers welcome
  • OHSU Knight Cancer Institute, Portland
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT07278440

The HOPE Biobank Resource (BMT CTN 2402 HOPE)

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health and Science University, Portland
All ages · All sexes · Updated Aug 27, 2026 · NCT07227155

ASSESS ALL ALS Study

RecruitingObservational studyHealthy volunteers welcome
  • Providence ALS Center, Portland
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06578195

PREVENT ALL ALS Study

RecruitingObservational studyHealthy volunteers welcome
  • Providence ALS Center, Portland
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06581861

Pimavanserin vs. Quetiapine for Treatment of Parkinson's Psychosis

RecruitingPhase 4Healthy volunteers welcome
  • VA Portland Health Care System, Portland, OR, Portland
Ages 40 and older · All sexes · Updated Aug 19, 2026 · NCT04373317

Sleep Duration and Cardiovascular Health

RecruitingHealthy volunteers welcome
  • Oregon Health and Science University, Portland
Ages 25 to 65 · All sexes · Updated Aug 4, 2026 · NCT04804124

PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health &Science University, Portland
Ages 30 and older · All sexes · Updated Jul 27, 2026 · NCT04477785

Pancreatic Cancer Early Detection Consortium

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health & Science University, Portland
Ages 18 to 90 · All sexes · Updated Jul 22, 2026 · NCT04970056

Comprehensive HHT Outcomes Registry of the United States (CHORUS)

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health and Science University, Portland
All ages · All sexes · Updated Jul 17, 2026 · NCT06259292

Identifying and Caring for Individuals With Inherited Cancer Syndrome

RecruitingHealthy volunteers welcome
  • Providence Portland Medical Center, Portland
  • OHSU Knight Cancer Institute, Portland
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT04494945

Disparities in Emergency Contraceptive Metabolism Dictate Efficacy

RecruitingPhase 4Healthy volunteers welcome
  • OHSU, Portland
Ages 18 to 40 · Women · Updated Jul 9, 2026 · NCT05674513

The Society for Obstetric Anesthesia and Perinatology Research Network General Anesthesia Registry

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health & Science University, Portland
Ages 15 to 55 · Women · Updated Jun 4, 2026 · NCT06030063

Galleri® in the Medicare Population.

RecruitingHealthy volunteers welcome
  • OHSU CEDAR Clinical Trials Portland, Portland
  • OHSU CEDAR Clinical Trials Richmond, Portland
Ages 50 and older · All sexes · Updated May 22, 2026 · NCT05673018

Prostate Cancer Screening for People at Genetic Risk for Aggressive Disease, PATROL Study

RecruitingObservational studyHealthy volunteers welcome
  • OHSU Knight Cancer Institute, Portland
Ages 40 and older · Men · Updated May 15, 2026 · NCT04472338

Using EMA Data to Inform a Web-intervention for Couples Concerned About Drinking

RecruitingHealthy volunteers welcome
  • Portland State University, Portland
Ages 18 and older · All sexes · Updated Apr 27, 2026 · NCT06501677

Mediators and Moderators of Auditory Training

RecruitingHealthy volunteers welcome
  • Oregon Health & Science University, Portland
Ages 18 to 85 · All sexes · Updated Apr 20, 2026 · NCT06812273

Methylphenidate for the Treatment of Epilepsy-related Cognitive Deficits

RecruitingPhase 4Healthy volunteers welcome
  • VA Portland Health Care System, Portland, OR, Portland
Ages 18 and older · All sexes · Updated Apr 20, 2026 · NCT04419272

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

RecruitingPhase 3Healthy volunteers welcome
  • Providence Portland Medical Center, Portland
  • Providence Saint Vincent Medical Center, Portland
  • Providence Willamette Falls Medical Center, Oregon City · 12 mi away
Ages 18 and older · All sexes · Updated Mar 31, 2026 · NCT07018869

Beat Childhood Cancer Specimen Banking and Data Registry

RecruitingObservational studyHealthy volunteers welcome
  • Randall Children's Hospital, Portland
All ages · All sexes · Updated Feb 3, 2026 · NCT04715178

Montalcino Aortic Consortium: Precision Medicine for Heritable Thoracic Aortic Disease

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health & Science University, Portland
All ages · All sexes · Updated Feb 2, 2026 · NCT04005976

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health Sciences University, Portland
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881

Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) Study

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health & Science University, Portland
Ages 18 and older · All sexes · Updated Jan 15, 2026 · NCT05677880

Insights in Endocervical Mucus Secretion

RecruitingPhase 4Healthy volunteers welcome
  • Oregon Health & Science University, Portland
Ages 21 to 40 · Women · Updated Jan 8, 2026 · NCT07111247

CGM for the Early Detection and Management of Hyperglycemia in Pregnancy

RecruitingHealthy volunteers welcome
  • Oregon Health & Science University, Portland
Ages 18 and older · Women · Updated Dec 23, 2025 · NCT06957028

Diaphragmatic Hernia Research & Exploration, Advancing Molecular Science

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health & Science University, Doernbecher Children's Hospital, Portland
All ages · All sexes · Updated Dec 12, 2025 · NCT00950118

The Influence of Sleep on Cardiovascular Outcomes

RecruitingHealthy volunteers welcome
  • Oregon Health & Science University, Portland
Ages 18 to 50 · All sexes · Updated Nov 10, 2025 · NCT06535178

Food and Circadian Timing

RecruitingHealthy volunteers welcome
  • Oregon Health & Science University, Portland
Ages 18 to 40 · All sexes · Updated Nov 10, 2025 · NCT04743271

STELLA-FTD: Examination of a Behavior Change Intervention for FTD Family Care Partners

RecruitingHealthy volunteers welcome
  • Oregon Health & Science University, Portland
Ages 18 to 100 · All sexes · Updated Oct 27, 2025 · NCT06613204

Support Via Technology: Living and Learning With Advancing Dementia-REVISED

RecruitingHealthy volunteers welcome
  • Oregon Health & Science University, Layton Aging and Alzheimer's Disease Research Center, Portland
Ages 18 and older · All sexes · Updated Oct 23, 2025 · NCT06460012

Comparative Effectiveness of Cryoablation Versus Steroid and Lidocaine Alone for Treatment of Morton's Neuroma

RecruitingHealthy volunteers welcome
  • Oregon Health Sciences University, Portland
Ages 18 to 105 · All sexes · Updated Oct 16, 2025 · NCT05501262

Magnetic Resonance Imaging and Biomarkers for Muscular Dystrophy

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health and Science University, Portland
Ages 5 to 62 · Men · Updated Oct 15, 2025 · NCT01484678

OCT Angiography and NRAI in Dementia

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health & Science University, Portland
Ages 55 and older · All sexes · Updated Sep 12, 2025 · NCT03761381

Observational Study of Iris Tumors

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health & Science University, Portland
Ages 18 and older · All sexes · Updated Sep 9, 2025 · NCT03809585

OCT in Diagnosis of Irregular Corneas

RecruitingObservational studyHealthy volunteers welcome
  • Humberto Martinez, Portland
Ages 14 to 85 · All sexes · Updated Sep 9, 2025 · NCT03504800

Effect of Abdominal Wall Injections on Abdominal Pain

RecruitingPhase 4Healthy volunteers welcome
  • OHSU, Portland
  • Oregon Health Sciences University, Portland
Ages 18 to 100 · All sexes · Updated Sep 2, 2025 · NCT06121466

Immunogenicity of Yellow Fever Vaccine 17D in Adults With Prior 17D Vaccination

RecruitingPhase 1/2Healthy volunteers welcome
  • Oregon Health & Science University, Portland
Ages 20 to 49 · All sexes · Updated Jul 31, 2025 · NCT05859490

Effects of a Specific Substance in Smokers

RecruitingHealthy volunteers welcome
  • Oregon Health and Science University, Portland
Ages 21 to 40 · All sexes · Updated Jul 28, 2025 · NCT04281979

Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia

RecruitingHealthy volunteers welcome
  • Oregon Health & Science University, Portland
Ages 18 to 120 · All sexes · Updated Jul 25, 2025 · NCT05237258

Quantification & Classification of Inflammatory Cells in Uveitis Using OCT

RecruitingObservational studyHealthy volunteers welcome
  • Casey Eye Institute - Oregon Health & Science University, Portland
Ages 5 to 85 · All sexes · Updated Jul 17, 2025 · NCT07065747

EMBRACE: Exercising Together

RecruitingPhase 2Healthy volunteers welcome
  • OHSU Knight Cancer Institute, Portland
Ages 18 and older · All sexes · Updated May 29, 2025 · NCT06049355

Diet and Active Lifestyle - Yuuyaraq (The Yup'ik Way of Life)

RecruitingHealthy volunteers welcome
  • Oregon Health and Science University, Portland
Ages 18 and older · All sexes · Updated May 7, 2025 · NCT06629610

The ME&MG Digital Solution for Autonomous Assessment of Myasthenia Gravis

RecruitingHealthy volunteers welcome
  • OHSU, Portland
Ages 18 and older · All sexes · Updated Apr 11, 2025 · NCT05564936

Focus Groups in Ethnically and Racially Diverse Families

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health & Science University, Portland
Ages 18 to 80 · All sexes · Updated Apr 4, 2025 · NCT05930886

Endometrial Biopsy in Progestin Contraceptive Users

RecruitingEarly phase 1Healthy volunteers welcome
  • OHSU, Portland
Ages 18 to 40 · Women · Updated Mar 20, 2025 · NCT05760144

Monoferric for Prenatal Iron Deficiency

RecruitingEarly phase 1Healthy volunteers welcome
  • Oregon Health & Science Univerity, Portland
Ages 18 to 65 · Women · Updated Sep 19, 2024 · NCT05763043

Sex Differences in Trauma, Inflammation and Brain Function and the Implications for Treatment Efficacy in Alcohol Use Disorder

RecruitingPhase 4Healthy volunteers welcome
  • VA Portland Health Care System, Portland
Ages 18 to 60 · All sexes · Updated Jul 18, 2024 · NCT06426303

The Parkinson's Genetic Research Study

RecruitingObservational studyHealthy volunteers welcome
  • Portland VA Medical Center, Portland
Ages 18 and older · All sexes · Updated May 14, 2024 · NCT01558479

Reaching Out to Distressed Medical Residents, Fellows and Faculty

RecruitingHealthy volunteers welcome
  • Oregon Health and Science University, Portland
Ages 18 and older · All sexes · Updated Apr 30, 2024 · NCT02010866

Total Intravenous Versus Inhalational Anesthesia- A Geriatric Anesthesia Study

RecruitingPhase 4Healthy volunteers welcome
  • Oregon Health & Science University, Portland
Ages 70 to 110 · All sexes · Updated Apr 8, 2024 · NCT06036095

Sleep and Metabolism

RecruitingHealthy volunteers welcome
  • Oregon Health & Science University, Portland
Ages 18 to 40 · All sexes · Updated Apr 3, 2024 · NCT05775627

Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health and Science University, Portland
Ages 18 and older · All sexes · Updated Feb 28, 2024 · NCT01574053

OCT Angiography in Wet AMD

RecruitingObservational studyHealthy volunteers welcome
  • Casey Eye Institute, Oregon Health & Science University, Portland
Ages 50 to 100 · All sexes · Updated Feb 12, 2024 · NCT02253030

Clinical and Genetic Analysis of ROP

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health & Science University, Portland
Up to age 1 · All sexes · Updated Apr 20, 2022 · NCT04420156

Augmentation of Limb Perfusion With Contrast Ultrasound

RecruitingHealthy volunteers welcome
  • OHSU, Portland
Ages 19 to 99 · All sexes · Updated Aug 23, 2018 · NCT03195556

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.