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Breast Cancer clinical trials in San Antonio, TX

47 studies for Breast Cancer are looking for participants at sites in and around San Antonio (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies

RecruitingPhase 1/2
  • Research Site, San Antonio
Ages 18 to 130 · All sexes · Updated Oct 5, 2026 · NCT05417594

Phase 1 Study of OP-3136 in Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • START - San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT06784193

A Study of PHST001 in Advanced Solid Tumors

RecruitingPhase 1
  • START Center for Cancer Research - San Antonio, San Antonio
  • University of Texas (UT) Health, San Antonio
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT06840886

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • New Experimental Therapeutics of San Antonio - NEXT Oncology, San Antonio
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Audie L Murphy VA Hospital, San Antonio
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer

RecruitingPhase 2
  • UT Health San Antonio, Mays Cancer Center, San Antonio
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07102381

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

RecruitingPhase 1
  • University of Texas San Antonio (UTSA), San Antonio
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06625775

Anti-Ly6E Exatecan ADC M7437 in Advanced Solid Tumors

RecruitingPhase 1
  • NEXT Oncology - PARENT, San Antonio
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07360314

BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors

RecruitingPhase 1
  • Next Oncology, San Antonio
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06120283

A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)

RecruitingPhase 3
  • Mays Cancer Center ( Site 0049), San Antonio
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07060807

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

RecruitingPhase 3
  • Texas Oncology - San Antonio ( Site 8004), San Antonio
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06966700

Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

RecruitingPhase 3
  • Clinical Trial Site, San Antonio
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07085767

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

RecruitingPhase 3
  • Texas Oncology - San Antonio Medical Center, San Antonio
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07174336

A Study of JNJ-101684362 (HLD-0117) in Patients With Metastatic Breast Cancer

RecruitingPhase 1
  • South Texas Accelerated Research Therapeutics, LLC (START), San Antonio
Ages 18 and older · Women · Updated Sep 21, 2026 · NCT07524855

A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

RecruitingPhase 1/2
  • START Center for Cancer Research, San Antonio
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07109726

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

RecruitingPhase 3
  • Mays Cancer Center, San Antonio
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06492616

Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors

RecruitingPhase 1
  • START - San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06293898

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • NEXT Oncology, San Antonio
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06440005

A Study of LOXO-783 in Patients With Breast Cancer/Other Solid Tumors

RecruitingPhase 1
  • South Texas Accelerated Research Therapeutics (START), San Antonio
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT05307705

Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.

RecruitingPhase 3
  • Texas Oncology-San Antonio Cancer Care, San Antonio
  • Texas Oncology - San Antonio Northeast, San Antonio
  • Texas Oncology - San Antonio Stone Oak, San Antonio
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06072612

A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors

RecruitingPhase 1
  • South Texas Accelerated Research Therapeutics (START) San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT07029399

Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma

RecruitingPhase 1
  • START San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT06582017

A Phase 1 Study of LNCB74 in Advanced Solid Tumors

RecruitingPhase 1
  • UT Health San Antonio - MD Anderson Cancer Center, San Antonio
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT06774963

Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

RecruitingPhase 3
  • The University of Texas Health Sciences Center at San Antonio - Mays Cancer Center, San Antonio
  • Texas Oncology - San Antonio Medical Center, San Antonio
Ages 18 to 100 · All sexes · Updated Aug 6, 2026 · NCT05232916

IDOV-Immune for Advanced Solid Tumors

RecruitingPhase 1
  • South Texas Accelerated Research Therapeutics, San Antonio
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06910657

Study of GVV858 as a Single Agent or in Combination With Endocrine Therapy in Patients With HR+/HER2- Breast Cancer and Other Advanced Solid Tumors

RecruitingPhase 1/2
  • START, San Antonio
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT07288359

Study of RGT-490 in Patients With PIK3CA-Mutated Advanced Solid Tumors

RecruitingPhase 1
  • NEXT San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT07524322

A Study to Learn About the Study Medicine Called PF-08032562 in People With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • START San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT07318805

First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • START San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT05768139

Sapanisertib and Serabelisib (PIKTOR) in Various Combinations in Patients With HR+/HER2- Advanced/Metastatic Breast Cancer

RecruitingPhase 1/2
  • START San Antonio, San Antonio
  • Texas Oncology - San Aantonio, San Antonio
Ages 18 and older · All sexes · Updated Jul 2, 2026 · NCT07558733

Phase 1/2 Study of ETX-636 in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • START, San Antonio
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT06993844

CD40 Agonist, Flt3 Ligand, and Chemotherapy in HER2 Negative Breast Cancer

RecruitingPhase 1
  • The University of Texas Health Science Center at San Antonio, San Antonio
Ages 18 to 99 · All sexes · Updated Jun 17, 2026 · NCT05029999

Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2)

RecruitingPhase 3
  • Mays Cancer Center, San Antonio
Ages 18 and older · All sexes · Updated May 18, 2026 · NCT06757634

Impact of Ketogenic Diet on Tumor Microenvironment in Patients With Breast Cancer

Recruiting
  • Mays Cancer Center, UT Health San Antonio, San Antonio
Ages 18 and older · All sexes · Updated May 8, 2026 · NCT07574671

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

RecruitingPhase 1/2
  • NEXT Oncology, San Antonio
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT06239194

Phase I Study of SYS6043 in Patients With Advanced/Metastatic Solid Tumors

RecruitingPhase 1
  • NEXT Oncology San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Apr 7, 2026 · NCT07424547

Study of Tucatinib and Doxil in Participants With Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Metastatic Breast Cancer

RecruitingPhase 2
  • Texas Oncology- San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Mar 20, 2026 · NCT05748834

A Phase 1/2 Clinical Trial to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of HMBD-501 in Patients With HER3-Expressing Solid Tumors

RecruitingPhase 1/2
  • Research Site, San Antonio
Ages 18 and older · All sexes · Updated Mar 2, 2026 · NCT06956690

Phase 1/2 Dose Finding, Safety and PK Study in Advanced Refractory Solid Tumors

RecruitingPhase 1/2
  • START San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Feb 17, 2026 · NCT07145255

A Phase 1 Study of XL309 (ISM3091) Alone and in Combination in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #3, San Antonio
Ages 18 and older · All sexes · Updated Sep 5, 2025 · NCT05932862

MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles

RecruitingObservational study
  • Texas Oncology, PA - Metropolitan, San Antonio
  • Texas Oncology, PA - Northeast, San Antonio
  • UT Health Cancer Center, San Antonio
  • and 2 more
Ages 18 and older · All sexes · Updated Aug 20, 2025 · NCT03053193

A Phase 2 Study of PCS6422 With Capecitabine in Patients With Advanced or Metastatic Breast Cancer

RecruitingPhase 2
  • Texas Oncology PA (San Antonio), San Antonio
Ages 18 and older · All sexes · Updated Jun 19, 2025 · NCT06568692

Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of BTX-9341 in Advanced and/or Metastatic Breast Cancer

RecruitingPhase 1
  • Biotheryx Investigative Site, San Antonio
Ages 18 and older · All sexes · Updated Jun 6, 2025 · NCT06515470

About Breast Cancer

Breast cancer is a cancer that starts in the breast tissue, when cells change and grow out of control. These extra cells can form a mass called a tumor.

More about Breast Cancer on MedlinePlus

Breast Cancer trials in other cities

Other studies in San Antonio

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.