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Multiple Myeloma clinical trials in Rochester, MN

24 studies for Multiple Myeloma are looking for participants at sites in and around Rochester (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Understanding the Mechanisms of Clonal and Non-clonal Cytopenia Following CAR-T Therapy for Multiple Myeloma or CD19+ Lymphoproliferative Disorder (LPD)

Recruiting
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06630104

SMS-Based Remote Symptom Monitoring for Patients With Plasma Cell Disorders

RecruitingObservational study
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07850284

A Study Comparing JNJ-79635322 and Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma

RecruitingPhase 3
  • Mayo Clinic, Rochester
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07518186

A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma

RecruitingPhase 3
  • Mayo Clinic Rochester, Rochester
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07258511

A Study to Compare Linvoseltamab and Daratumumab Treatment in High-Risk Smoldering Multiple Myeloma (HR-SMM)

RecruitingPhase 3
  • Mayo Clinic, Rochester
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07393282

A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel

RecruitingPhase 4
  • Mayo Clinic Rochester, Rochester
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05201781

Testing Teclistamab (TECVAYLI) in Combination With Iberdomide for Relapsed or Refractory Multiple Myeloma

RecruitingPhase 1
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06465316

Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma

RecruitingPhase 2
  • Mayo Clinic in Rochester, Minnesota, Rochester
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT06297226

Study of SIM0500 Alone in Participants With Relapsed or Refractory Multiple Myeloma

RecruitingPhase 1
  • Mayo Clinic Rochester, Rochester
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT06375044

Dasatinib and Quercetin With CAR-T Therapy for the Treatment of Patients With Relapsed or Refractory Multiple Myeloma

RecruitingPhase 2
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT06940297

Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

RecruitingPhase 3
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT04566328

A Study of an MMSET Inhibitor in Patients With Relapsed and Refractory Multiple Myeloma

RecruitingPhase 1
  • Mayo Clinic - Transplant Center - Rochester, Rochester
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT05651932

AZD0120 in Relapsed/Refractory Multiple Myeloma (DURGA-1)

RecruitingPhase 1/2
  • Research Site, Rochester
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05850234

A Study to Evaluate the Efficacy of Cemsidomide + Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma

RecruitingPhase 2
  • Mayo Clinic - Minnesota, Rochester
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT07284758

A Study to Evaluate the Safety, Effectiveness and Tolerable Dose of Arlocabtagene Autoleucel (BMS-986393) in Novel Combinations in Participants With Relapsed and/or Refractory Multiple Myeloma

RecruitingPhase 1
  • Mayo Clinic in Rochester, Minnesota, Rochester
Ages 18 and older · All sexes · Updated Jul 16, 2026 · NCT06121843

A Study to Assess Adverse Events of Intravenously (IV) Infused Etentamig (ABBV-383) in Adult Participants With Relapsed or Refractory Multiple Myeloma

RecruitingPhase 1
  • Mayo Clinic - Rochester /ID# 251164, Rochester
Ages 18 and older · All sexes · Updated Jul 13, 2026 · NCT05650632

Elotuzumab, Daratumumab, Iberdomide, and Dexamethasone for the Treatment of Relapsed Multiple Myeloma

RecruitingPhase 1/2
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · All sexes · Updated Jun 25, 2026 · NCT06785415

Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

RecruitingPhase 3
  • Mayo Clinic in Rochester, Rochester
All ages · All sexes · Updated Jun 10, 2026 · NCT05561387

Remote Monitoring With Health-Coaching to Improve Quality of Life in Older Patients With Multiple Myeloma

Recruiting
  • Mayo Clinic in Rochester, Rochester
Ages 65 and older · All sexes · Updated Apr 13, 2026 · NCT06145581

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

RecruitingObservational studyHealthy volunteers welcome
  • Mayo Clinic, Rochester
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881

Family Study of Lymphoproliferative Disorders

RecruitingObservational studyHealthy volunteers welcome
  • Mayo Clinic, Rochester
Ages 18 to 100 · All sexes · Updated Oct 14, 2025 · NCT00626496

About Multiple Myeloma

Multiple myeloma is a cancer that begins in plasma cells, a type of white blood cell. Discover symptoms, diagnostic tests, and treatments for myeloma.

More about Multiple Myeloma on MedlinePlus

Multiple Myeloma trials in other cities

Other studies in Rochester

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.