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Parkinson's Disease clinical trials in Philadelphia, PA

14 studies for Parkinson's Disease are looking for participants at sites in and around Philadelphia (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

RecruitingPhase 2
  • Thomas Jefferson University Hospital, Philadelphia
Ages 40 to 80 · All sexes · Updated Oct 2, 2026 · NCT06680830

A Clinical Trial of LY3962681 in Healthy Volunteers and in Patients With Parkinson's Disease

RecruitingPhase 1Healthy volunteers welcome
  • University of Pennsylvania, Dept of Neurology, Philadelphia
Ages 30 to 80 · All sexes · Updated Oct 1, 2026 · NCT06565195

A Study of Buntanetap in Participants With PD

RecruitingPhase 2/3
  • Abington Neurology, Willow Grove · 13 mi away
Ages 40 to 85 · All sexes · Updated Sep 21, 2026 · NCT07284784

Parkinson's Foundation PD GENEration Genetic Registry

RecruitingObservational study
  • University of Pennsylvania, Philadelphia
  • Thomas Jefferson University, Philadelphia
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT04994015

A US Study That Observes How Parkinson's Disease Changes Over Time in Patients Who Still Have Movement Symptoms Despite Taking Parkinson's Medications

RecruitingObservational study
  • Thomas Jefferson University, Philadelphia
Ages 45 to 75 · All sexes · Updated Sep 4, 2026 · NCT07330258

A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

RecruitingPhase 3
  • University Pennsylvania Hospital, Philadelphia
Ages 50 to 85 · All sexes · Updated Sep 3, 2026 · NCT07174310

Biofluid Research on Age-Related or Inherited Neurodegeneration

RecruitingObservational studyHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT07798700

Using the EHR to Advance Genomic Medicine Across a Diverse Health System

Recruiting
  • Penn Medicine, Philadelphia
Ages 18 and older · All sexes · Updated Aug 14, 2026 · NCT06377033

PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

RecruitingObservational studyHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 30 and older · All sexes · Updated Jul 27, 2026 · NCT04477785

Study of Biodistribution, Metabolism, Excretion and Brain Uptake11C-M503

RecruitingEarly phase 1Healthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 40 to 85 · All sexes · Updated Apr 24, 2026 · NCT06303921

Study of Biodistribution, Metabolism, Excretion and Brain Uptake 18F-JSS20-183A

RecruitingEarly phase 1
  • University of Pennsylvania, Philadelphia
Ages 40 to 85 · All sexes · Updated Dec 23, 2025 · NCT06932809

Parkinson's Disease and Movement Disorders Clinical Database

RecruitingObservational study
  • University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Oct 7, 2025 · NCT04997642

Adaptive Neurostimulation to Restore Sleep in Parkinson's Disease (Aim 2)

Recruiting
  • University of Pennsylvania Health System, Philadelphia
Ages 18 to 80 · All sexes · Updated Jul 22, 2025 · NCT05070013

About Parkinson's Disease

Parkinson's disease (PD) is a movement disorder. It causes tremors, stiffness, and slow movement. It gets worse over time. Learn what can help.

More about Parkinson's Disease on MedlinePlus

Parkinson's Disease trials in other cities

Other studies in Philadelphia

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.