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Metastatic Cancer clinical trials in San Antonio, TX

44 studies for Metastatic Cancer are looking for participants at sites in and around San Antonio (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma

RecruitingPhase 3
  • Texas Oncology - San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT07562152

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

RecruitingPhase 1
  • South Texas Accelerated Research Therapeutics (START), San Antonio
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06465069

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • New Experimental Therapeutics of San Antonio - NEXT Oncology, San Antonio
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

RecruitingPhase 1
  • University of Texas San Antonio (UTSA), San Antonio
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06625775

A Study of ASP3082 in Adults With Advanced Solid Tumors

RecruitingPhase 1
  • NEXT Oncology, San Antonio
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT05382559

A Study of NEOK001, a B7-H3 and ROR1 Targeting Bispecific ADC in Participants With Select Solid Tumors

RecruitingPhase 1
  • NEXT Oncology, San Antonio
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07612176

SLV-154 Treatment of Advanced Cancers

RecruitingPhase 1
  • Mays Cancer Center; University of Texas Health San Antonio, San Antonio
Ages 12 and older · All sexes · Updated Sep 22, 2026 · NCT06771219

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

RecruitingPhase 3
  • Texas Oncology - San Antonio Medical Center, San Antonio
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07174336

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

RecruitingPhase 1/2
  • NEXT Oncology San Antonio, San Antonio
  • START Texas, San Antonio
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

RecruitingPhase 1/2
  • START South Texas Accelerated Research Therapeutics, San Antonio
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT05267626

CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Clinical Study Site, San Antonio
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT07335497

Multiple Dose Intraventricular Administration of Rhenium-186 NanoLiposome for Leptomeningeal Metastases

RecruitingPhase 1/2
  • The Cancer Therapy and Research Center at UTHSCSA, San Antonio
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07098806

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • NEXT Oncology, San Antonio
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06440005

AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)

RecruitingPhase 1/2
  • Avenzo Therapeutics Recruiting Site, San Antonio
Ages 18 to 75 · All sexes · Updated Sep 4, 2026 · NCT07038343

A Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity and Anti-tumour Activity of IPN01203 in Adults With Locally Advanced or Metastatic Solid Tumours Exposed to Immune Checkpoint Inhibitor Therapies

RecruitingPhase 1/2
  • South Texas Accelerated Research Therapeutics (START) - San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT07213830

Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.

RecruitingPhase 3
  • Texas Oncology-San Antonio Cancer Care, San Antonio
  • Texas Oncology - San Antonio Northeast, San Antonio
  • Texas Oncology - San Antonio Stone Oak, San Antonio
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06072612

A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors

RecruitingPhase 1
  • South Texas Accelerated Research Therapeutics (START) San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT07029399

A Study of BGB-B455 in Adults With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Next Oncology, San Antonio
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06803680

FOG-001 in Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • South Texas Accelerated Research Therapeutics, LLC, San Antonio
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

A Study of mRNA-4106 or mRNA-4200 Administered Alone or in Combination With Anti-Cancer Agents in Participants With Solid Tumors

RecruitingPhase 1
  • START San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT06880549

IDOV-Immune for Advanced Solid Tumors

RecruitingPhase 1
  • South Texas Accelerated Research Therapeutics, San Antonio
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06910657

A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Texas Oncology - San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT04657068

A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • START San Antonio, LLC., San Antonio
Ages 18 and older · All sexes · Updated Jul 15, 2026 · NCT06657144

A Clinical Study of KTX-2001 in Subjects With Metastatic Castration-Resistant Prostate Cancer (STRIKE-001)

RecruitingPhase 1
  • USA Clinical Trials, San Antonio
Ages 18 and older · Men · Updated Jul 9, 2026 · NCT07103018

A Study of PYX-201 in Advanced Solid Tumors

RecruitingPhase 1
  • NEXT San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Jun 30, 2026 · NCT05720117

A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

RecruitingPhase 1
  • NEXT Oncology, San Antonio
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT07458347

LUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLC

RecruitingPhase 3
  • Jason Bates at University of Texas Health Science Center, San Antonio
Ages 18 and older · All sexes · Updated Jun 25, 2026 · NCT06216301

A Study of XB628 Alone and in Combination With Zanzalintinib in Participants With Recurrent Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #2, San Antonio
Ages 18 and older · All sexes · Updated Jun 24, 2026 · NCT06952010

First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Research Site, San Antonio
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT07284186

CT-95 in Advanced Cancers Associated With Mesothelin Expression

RecruitingPhase 1
  • Context Investigational Site, San Antonio
  • Context Investigational Site, San Antonio
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT06756035

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

RecruitingPhase 1
  • Research Site #2, San Antonio
  • Research Site, San Antonio
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06835569

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

RecruitingPhase 1
  • START, San Antonio
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06040541

Dose-Escalation and Dose-Expansion Study of BSI-082 Monotherapy and Combined Therapy in Patients With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • University of Texas Health Science Center at San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT07086768

BBO-11818 in Adult Subjects With KRAS Mutant Cancer

RecruitingPhase 1
  • NEXT Oncology, San Antonio
Ages 18 and older · All sexes · Updated Jun 2, 2026 · NCT06917079

Study of Sacituzumab Govitecan in Participants With Advanced or Metastatic Solid Tumor and Moderate Liver Impairment

RecruitingPhase 1
  • Texas Liver Institute, San Antonio
  • NEXT Oncology, San Antonio
Ages 18 and older · All sexes · Updated Jun 2, 2026 · NCT04617522

Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2)

RecruitingPhase 3
  • Mays Cancer Center, San Antonio
Ages 18 and older · All sexes · Updated May 18, 2026 · NCT06757634

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

RecruitingPhase 1/2
  • Next Oncology, San Antonio
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT05379985

A First-In Human (FIH) Study to Find Out How Well REGN10597 Medicine Given Alone or in Combination With Cemiplimab Works in Adult Participants Who Have Cancer With Tumors That Have Spread in Their Body

RecruitingPhase 1/2
  • Next Oncology, San Antonio
  • The Start Center for Cancer Care, San Antonio
Ages 18 and older · All sexes · Updated Apr 28, 2026 · NCT06413680

A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

RecruitingPhase 1/2
  • South Texas Accelerated Research Therapeutics, LLC, San Antonio
  • UT Health San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Mar 18, 2026 · NCT06244771

An Open-Label Study of INV-1120 as a Single Agent and in Combination With Pembrolizumab in Adult Patients With Advanced Solid Tumors

RecruitingPhase 1
  • UT Health, San Antonio
Ages 18 and older · All sexes · Updated Mar 18, 2026 · NCT04443088

Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • START San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Feb 18, 2026 · NCT07030257

A Study of ERAS-4001 in Patients With Advanced or Metastatic Solid Tumors.

RecruitingPhase 1
  • NEXT Oncology, San Antonio
Ages 18 to 99 · All sexes · Updated Dec 3, 2025 · NCT07021898

A Study of OR502, a Monoclonal Antibody Targeting LILRB2, Alone and in Combination With Anticancer Agents

RecruitingPhase 1/2
  • NEXT Oncology, San Antonio
Ages 18 and older · All sexes · Updated Jan 7, 2025 · NCT06090266

Metastatic Cancer trials in other cities

Other studies in San Antonio

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.