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Colorectal Cancer clinical trials in Detroit, MI

26 studies for Colorectal Cancer are looking for participants at sites in and around Detroit (within about 30 miles). Open a study to see who can join and how to contact the study team.

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The Vanguard Study: Testing a New Way to Screen for Cancer

RecruitingHealthy volunteers welcome
  • Henry Ford Hospital, Detroit
  • Henry Ford Medical Center - Detroit Northwest, Detroit
Ages 45 to 75 · All sexes · Updated Oct 5, 2026 · NCT06995898

Colonoscopy vs Stool Testing for Older Adults With Colon Polyps

Recruiting
  • Henry Ford, Detroit
Ages 65 to 82 · All sexes · Updated Oct 2, 2026 · NCT05612347

Family Communications After Genetic Testing

RecruitingHealthy volunteers welcome
  • Henry Ford Health Saint John Hospital, Detroit
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07143487

Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial

RecruitingPhase 2
  • Henry Ford Hospital, Detroit
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT05673148

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Henry Ford Hospital, Detroit
  • Henry Ford Health Saint John Hospital, Detroit
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #65, Detroit
  • Exelixis Clinical Site #13, Detroit
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

RecruitingPhase 1
  • Barbara Ann Karmanos Cancer Institute, Detroit
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07114601

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

RecruitingPhase 1
  • Barbara Ann Karmanos Cancer Institute, Detroit
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07213791

A Study to Investigate the Safety and Preliminary Efficacy of GSK5460025 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors

RecruitingPhase 1/2
  • GSK Investigational Site, Detroit
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07213609

Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer

RecruitingPhase 3
  • Clinical Study Site, Detroit
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT07228832

MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors

RecruitingPhase 1
  • Barbara Ann Karmanos Cancer Institute, Detroit
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06586515

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Karmanos Cancer Institute, Detroit
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT05592626

Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Investigative Site #120, Detroit
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT06974110

A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • Henry Ford Health System, Detroit
Ages 18 and older · All sexes · Updated Jul 15, 2026 · NCT06657144

Culturally Adapting an Intervention to Increase Genetic Testing in African American Cancer Survivors

Recruiting
  • Karmanos Cancer Institute, Detroit
Ages 20 to 79 · All sexes · Updated Jun 23, 2026 · NCT07436078

A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types

RecruitingPhase 1
  • Karmanos Cancer Institute, Detroit
Ages 18 and older · All sexes · Updated Jun 18, 2026 · NCT07503808

KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

RecruitingPhase 1
  • Henry Ford Health System, Detroit
Ages 18 and older · All sexes · Updated Jun 8, 2026 · NCT06026410

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

RecruitingPhase 3Healthy volunteers welcome
  • Henry Ford Health Saint John Hospital, Detroit
Ages 18 and older · All sexes · Updated Mar 31, 2026 · NCT07018869

A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

RecruitingPhase 1/2
  • Karmanos Cancer Institute, Detroit
Ages 18 and older · All sexes · Updated Mar 18, 2026 · NCT06244771

Sacituzumab Govitecan in Combination With Capecitabine for Advanced Gastrointestinal Cancers After Progression on Standard Therapy

RecruitingPhase 1
  • Henry Ford Cancer-Detroit, Detroit
Ages 18 and older · All sexes · Updated Dec 19, 2025 · NCT06065371

Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors

RecruitingPhase 1
  • Henry Ford Cancer Institute, Detroit
Ages 18 and older · All sexes · Updated Dec 17, 2025 · NCT05856981

A Beta-only IL-2 ImmunoTherapY Study

RecruitingPhase 1/2
  • Karmanos Cancer Institute, Detroit
Ages 18 and older · All sexes · Updated Jul 9, 2025 · NCT05086692

About Colorectal Cancer

Colorectal cancer starts in the colon or rectum. It may not cause symptoms at first. Screening tests can help find it early, when treatment is most effective.

More about Colorectal Cancer on MedlinePlus

Colorectal Cancer trials in other cities

Other studies in Detroit

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.