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Colorectal Cancer clinical trials in Springfield, MO

11 studies for Colorectal Cancer are looking for participants at sites in and around Springfield (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Family Communications After Genetic Testing

RecruitingHealthy volunteers welcome
  • Mercy Hospital Springfield, Springfield
  • CoxHealth South Hospital, Springfield
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07143487

Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial

RecruitingPhase 2
  • Mercy Hospital Springfield, Springfield
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT05673148

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Mercy Hospital Springfield, Springfield
  • CoxHealth South Hospital, Springfield
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer

RecruitingPhase 3
  • Clinical Study Site, Springfield
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT07228832

Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies (ELEPHAS-05)

RecruitingObservational study
  • Mercy Hospital - SPG, Springfield
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT07327489

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

RecruitingPhase 3Healthy volunteers welcome
  • Mercy Hospital Springfield, Springfield
  • CoxHealth South Hospital, Springfield
Ages 18 and older · All sexes · Updated Mar 31, 2026 · NCT07018869

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Mercy Hospital Springfield, Springfield
  • Cox Health South Hospital, Springfield
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia

RecruitingObservational study
  • Mercy Hospital Springfield, Springfield
Ages 18 and older · All sexes · Updated Jan 9, 2026 · NCT06073431

Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer

RecruitingObservational study
  • Mercy Hospital Springfield, Springfield
  • CoxHealth South Hospital, Springfield
Ages 60 and older · All sexes · Updated Jan 8, 2026 · NCT03998202

Tempus CRC Surveillance Study: A ctDNA Biomarker Profiling Study of Patients With CRC Using NGS Assays

RecruitingObservational study
  • Mercy Clinic Cancer and Hematology - Chub O'Reilly Cancer Center, Springfield
Ages 18 and older · All sexes · Updated May 6, 2025 · NCT05234177

About Colorectal Cancer

Colorectal cancer starts in the colon or rectum. It may not cause symptoms at first. Screening tests can help find it early, when treatment is most effective.

More about Colorectal Cancer on MedlinePlus

Colorectal Cancer trials in other cities

Other studies in Springfield

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.