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Heart Diseases clinical trials in New York City, NY

18 studies for Heart Diseases are looking for participants at sites in and around New York City (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Transition to KPL-387 Monotherapy Dosing & Administration Study

RecruitingPhase 2
  • Investigational Site 011, New York
  • Investigational Site 003, New York
Ages 18 to 80 · All sexes · Updated Sep 30, 2026 · NCT07288216

A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)

Recruiting
  • Columbia University Irving Medical Center/NewYork-Presbyterian Hospital, New York
  • Weill Medical College of Cornell University, New York
Ages 18 to 85 · All sexes · Updated Sep 28, 2026 · NCT07286578

Capitalizing on AI to CapTure Undiagnosed Structural Heart Disease

Recruiting
  • Columbia University Irving Medical Center / NewYork-Presbyterian, New York
Ages 40 and older · All sexes · Updated Sep 25, 2026 · NCT07843004

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

Recruiting
  • NYU Langone Medical Center, New York
  • The Mount Sinai Hospital, New York
  • New York-Presbyterian Hospital Columbia University Medical Center, New York
  • and 1 more
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT03242642

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

Recruiting
  • NYU Langone Health, New York
  • Mount Sinai, New York
  • Columbia University Irving Medical Center/ New York Presbyterian Hospital, New York
  • and 1 more
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031

Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)

Recruiting
  • Icahn School of Medicine at Mount Sinai, New York
Ages 18 to 85 · All sexes · Updated Sep 3, 2026 · NCT06703489

Abbott Structural Heart Device Registry

RecruitingObservational study
  • Mount Sinai Hospital, New York
  • New York Presbyterian Hospital/Cornell University, New York
All ages · All sexes · Updated Sep 1, 2026 · NCT06590467

A Preliminary Study for INFORMED

RecruitingPhase 4
  • Weill Cornell Medicine, New York
Ages 65 and older · All sexes · Updated Aug 21, 2026 · NCT05585125

Randomization of Single vs Multiple Arterial Grafts

Recruiting
  • Icahn School of Medicine, Mount Sinai, New York
  • Weil Cornell Medical College Department of Cardiothoracic Surgery, New York
  • Lenox Hill Hospital (Northwell), New York
  • and 1 more
Ages 18 to 70 · All sexes · Updated Aug 20, 2026 · NCT03217006

Reduction or Elimination of Mitral Regurgitation With the SATURN TMVR System (CASSINI-US)

Recruiting
  • Columbia University Irving Medical Center/New York Presbyterian Hospital, New York
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT07130994

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

RecruitingPhase 3
  • New York University (NYU) School of Medicine - Langone Medical Center, New York
  • Mount Sinai Hospital, New York
  • Columbia University Medical Center, New York
Ages 18 to 75 · All sexes · Updated Aug 4, 2026 · NCT06563895

Rectus Sheath Block in Cardiac Surgery

Recruiting
  • Mount Sinai Morningside Hospital Center, New York
Ages 18 to 85 · All sexes · Updated Jul 31, 2026 · NCT05833048

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

Recruiting
  • Mount Sinai West, New York
  • Mount Sinai, New York
  • Lenox Hill/ Northwell Health, New York
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

Recruiting
  • New York-Presbyterian/Columbia University Medical Center, New York
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195

The Relationship Between Blood Flow Readings During Surgery and How Well the Graft Stays Open and How Patients Recover Afterward in Coronary Artery Bypass Graft Surgery

Recruiting
  • Weill Cornell Medicine/NewYork Presbyterian Hospital, New York
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT07485738

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

Recruiting
  • Northwell Staten Island, New York
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152

Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women

Recruiting
  • Weill Cornell Medicine, New York
  • Columbia University Medical Center, New York
  • Lenox Hill Hospital, New York
Ages 18 and older · Women · Updated Apr 1, 2026 · NCT04124120

PARTNER 3 Trial - Aortic Valve-in-Valve

Recruiting
  • Cornell University, New York
  • Columbia University Medical Center/ New York Presbyterian Hospital, New York
All ages · All sexes · Updated May 10, 2024 · NCT03003299

About Heart Diseases

Heart disease is the leading cause of death in the U.S. Learn about the different types of heart diseases, and what you can do to try to prevent them.

More about Heart Diseases on MedlinePlus

Heart Diseases trials in other cities

Other studies in New York City

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.