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Melanoma clinical trials in Lexington, KY

10 studies for Melanoma are looking for participants at sites in and around Lexington (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • CommonSpirit Saint Joseph Hospital - Lexington, Lexington
  • Saint Joseph Radiation Oncology Resource Center, Lexington
  • CommonSpirit Saint Joseph Medical Center - East Lexington, Lexington
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)

RecruitingPhase 3
  • Markey Cancer Center Clinical Research Organization, Lexington
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06246916

Pan-tumor MRD Study

RecruitingObservational study
  • Baptist Health Lexington, Lexington
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06605404

Comparing the Effectiveness of Less Invasive Procedures With the Current Standard of Care for the Treatment of Older Adults With Early-Stage Melanoma

RecruitingPhase 3
  • CommonSpirit Saint Joseph Hospital - Lexington, Lexington
  • Saint Joseph Radiation Oncology Resource Center, Lexington
  • CommonSpirit Saint Joseph Medical Center - East Lexington, Lexington
  • and 1 more
Ages 75 and older · All sexes · Updated Sep 24, 2026 · NCT07068074

Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer

RecruitingPhase 1/2
  • University of Kentucky/Markey Cancer Center, Lexington
Ages 18 and older · All sexes · Updated Aug 31, 2026 · NCT05896839

Project: Every Child for Younger Patients With Cancer

RecruitingObservational study
  • University of Kentucky/Markey Cancer Center, Lexington
Up to age 25 · All sexes · Updated Aug 25, 2026 · NCT02402244

MC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced Melanoma

RecruitingPhase 1/2
  • University of Kentucky, Lexington
Ages 18 to 90 · All sexes · Updated Jun 10, 2026 · NCT05655312

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Saint Joseph Hospital East, Lexington
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

Nilotinib Plus Dabrafenib/Trametinib or Encorafenib/Binimetinib in Metastatic Melanoma

RecruitingPhase 1
  • Markey Cancer Center, Lexington
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT04903119

Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma

Recruiting
  • University of Kentucky, Lexington
Ages 18 and older · All sexes · Updated Nov 27, 2024 · NCT03860883

About Melanoma

Melanoma is the most serious type of skin cancer. Most have a black or black-blue area. Learn the 'ABCDE' of what to watch for and treatment options.

More about Melanoma on MedlinePlus

Melanoma trials in other cities

Other studies in Lexington

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.