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Ovarian Cancer clinical trials in Seattle, WA

30 studies for Ovarian Cancer are looking for participants at sites in and around Seattle (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

RecruitingPhase 2
  • Swedish Medical Center-First Hill, Seattle
All ages · All sexes · Updated Oct 5, 2026 · NCT05564377

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • University of Washington, Fred Hutchinson Cancer Center, Seattle
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

RecruitingObservational study
  • Fred Hutchinson Cancer Center, Seattle
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT04981119

A Study to Find Out How Safe REGN5668 is and How Well it Works In Adult Women When Given With Either Cemiplimab, or Cemiplimab + Fianlimab, or Ubamatamab

RecruitingPhase 1/2
  • Seattle Cancer Care Alliance at South Lake Union - G3630, Seattle
Ages 18 and older · Women · Updated Sep 24, 2026 · NCT04590326

A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer

RecruitingPhase 3
  • Swedish Medical Center, Seattle
  • Fred Hutchinson Cancer Center, Seattle
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07213804

A Study to Assess Adverse Events and Change in Disease Activity of Multiple Treatment Combinations With Intravenous Mirvetuximab Soravtansine in Adult Participants With Ovarian Cancer

RecruitingPhase 2
  • Virginia Mason Hospital and Medical Center /ID# 277259, Seattle
Ages 18 and older · Women · Updated Sep 22, 2026 · NCT07059845

Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

RecruitingPhase 1
  • University of Washington Fred Hutchinson, Seattle
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05983432

IGFBP-2 Vaccine to Prevent Ovarian Cancer Progression in Patients With Serologic Detection of Recurrence

RecruitingPhase 2
  • Fred Hutch/University of Washington Cancer Consortium, Seattle
Ages 18 and older · Women · Updated Sep 21, 2026 · NCT07495124

Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

RecruitingPhase 3
  • Virginia Mason Medical Center, Seattle
  • Fred Hutchinson Cancer Center, Seattle
Ages 18 and older · Women · Updated Sep 15, 2026 · NCT07214779

Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer

RecruitingPhase 2
  • Swedish Cancer Institute, Seattle
Ages 18 and older · Women · Updated Sep 14, 2026 · NCT06787612

A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

Recruiting
  • Swedish Medical Center-Ballard Campus, Seattle
  • Fred Hutchinson Cancer Center, Seattle
  • Swedish Medical Center-Cherry Hill, Seattle
  • and 3 more
Ages 35 to 50 · Women · Updated Aug 7, 2026 · NCT04251052

Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer

RecruitingPhase 3
  • Swedish Medical Center-Ballard Campus, Seattle
  • Fred Hutchinson Cancer Center, Seattle
  • Swedish Medical Center-Cherry Hill, Seattle
  • and 4 more
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT06580314

Study Evaluating the Safety and Efficacy of HWK-007, a PTK7-directed Antibody Drug Conjugate in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • Fred Hutchinson Cancer Center, Seattle
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT07444814

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

RecruitingPhase 1/2
  • Swedish Cancer Institute, Seattle
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT05579366

Clinical Pre-screening Protocol for Ovarian Cancer

RecruitingObservational study
  • Swedish Center for Research and Innovation, Seattle
Ages 18 and older · Women · Updated Jul 30, 2026 · NCT03877796

A Study of Raludotatug Deruxtecan (R-DXd) in Subjects With Platinum-resistant, High-grade Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

RecruitingPhase 2/3
  • University of Washington - Seattle Cancer Care Alliance, Seattle
Ages 18 and older · All sexes · Updated Jul 28, 2026 · NCT06161025

A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

RecruitingPhase 2
  • University of Washington School of Medicine, Seattle
Ages 8 and older · All sexes · Updated Jul 27, 2026 · NCT05503797

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

RecruitingPhase 1
  • Swedish Cancer Institute, Seattle
  • Swedish Medical Center, Seattle
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT04389632

A Study of Emiltatug Ledadotin (Emi-Le) in Participants With Solid Tumors

RecruitingPhase 1/2
  • Fred Hutchinson Cancer Center, Seattle
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05377996

Phase 1/2 Study of ETX-636 in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Fred Hutchinson Cancer Center, Seattle
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT06993844

Adapted Helping Ovarian Cancer Patients Cope Intervention to Address Burnout for Gynecologic Oncology Clinicians

RecruitingHealthy volunteers welcome
  • Fred Hutch/University of Washington Cancer Consortium, Seattle
Ages 18 and older · All sexes · Updated Jun 17, 2026 · NCT07282158

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

RecruitingPhase 1/2
  • Fred Hutchinson Cancer Center, Seattle
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT06051695

ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors

RecruitingPhase 1/2
  • Fred Hutchinson Cancer Center, Seattle
Ages 18 and older · All sexes · Updated May 13, 2026 · NCT03686124

Clonal Hematopoiesis and Therapy-Emergent Myeloid Neoplasms in Patients With Cancers, CHANCES Study

RecruitingObservational study
  • Fred Hutch/University of Washington Cancer Consortium, Seattle
All ages · All sexes · Updated Apr 17, 2026 · NCT06295965

TUBectomy With Delayed Oophorectomy in High Risk Women to Assess the Safety of Prevention

Recruiting
  • University of Washington, Seattle
Ages 25 to 50 · Women · Updated Apr 6, 2026 · NCT04294927

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

RecruitingPhase 1/2
  • Fred Hutchinson Cancer Center, Seattle
Ages 18 and older · All sexes · Updated Mar 27, 2026 · NCT06395519

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

RecruitingPhase 1
  • Fred Hutchinson Cancer Center, Seattle
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT06778863

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Seattle
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Developing a Test of Uterine Lavage for the Detection of Ovarian Cancer

RecruitingObservational study
  • The Swedish Hospital, Seattle
Ages 30 and older · Women · Updated Sep 16, 2025 · NCT04794322

About Ovarian Cancer

Ovarian cancer is a cancerous tumor that forms in the tissues of an ovary. The ovaries are a pair of female reproductive glands that make eggs and female hormones.

More about Ovarian Cancer on MedlinePlus

Ovarian Cancer trials in other cities

Other studies in Seattle

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.