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Melanoma clinical trials in Pittsburgh, PA
31 studies for Melanoma are looking for participants at sites in and around Pittsburgh (within about 30 miles). Open a study to see who can join and how to contact the study team.
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A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
RecruitingPhase 3
- University of Pittsburgh Medical Center (UPMC) Hillman Cancer Center, Pittsburgh
Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.
RecruitingPhase 3
- Allegheny Health Network, Pittsburgh
A Study on How to Safely Guide Surgery for Melanoma and Similar Skin Tumors in Children Using Pathology and Genetic Information
RecruitingPhase 2
- Children's Hospital of Pittsburgh of UPMC, Pittsburgh
Comparing the Effectiveness of Less Invasive Procedures With the Current Standard of Care for the Treatment of Older Adults With Early-Stage Melanoma
RecruitingPhase 3
- UPMC Hillman Cancer Center, Pittsburgh
A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases
RecruitingPhase 2
- University of Pittsburgh Cancer Institute (UPCI), Pittsburgh
A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant Tumors
RecruitingPhase 1/2
- University of Pittsburgh Medical Center, Pittsburgh
Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer
RecruitingPhase 1/2
- UPMC Hillman Cancer Center, Pittsburgh
Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors
RecruitingPhase 1/2
- Children's Hospital of Pittsburgh of UPMC, Pittsburgh
Project: Every Child for Younger Patients With Cancer
RecruitingObservational study
- Children's Hospital of Pittsburgh of UPMC, Pittsburgh
A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors
RecruitingPhase 1/2
- Research Site, Pittsburgh
Investigating Real-Time Immunotherapy Symptoms Study
Recruiting
- UPMC Hillman Cancer Center, Pittsburgh
Safety and Efficacy of OBX-115 in Advanced Solid Tumors
RecruitingPhase 1/2
- Allegheny Research Institute (Melanoma/NSCLC), Pittsburgh
Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies
RecruitingPhase 2
- UPMC Hillman Cancer Center, Pittsburgh
A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer
RecruitingPhase 1/2
- UPMC Hillman Cancer Center, Pittsburgh
Evolution of Metabolic and Immune Dysfunction in In-transit Melanoma
RecruitingObservational study
- UPMC Hillman Cancer Center, Pittsburgh
Evaluation of Hypoxia in Primary Melanoma
RecruitingObservational study
- UPMC Hillman Cancer Center, Pittsburgh
MC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced Melanoma
RecruitingPhase 1/2
- UPMC Hillman Cancer Center, Pittsburgh
ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors
RecruitingPhase 1/2
- University of Pittsburgh Medical Center, Pittsburgh
Neoadjuvant Darovasertib in Primary Uveal Melanoma
RecruitingPhase 3
- UPMC Hillman Cancer Center, Pittsburgh
A First-In Human (FIH) Study to Find Out How Well REGN10597 Medicine Given Alone or in Combination With Cemiplimab Works in Adult Participants Who Have Cancer With Tumors That Have Spread in Their Body
RecruitingPhase 1/2
- University of Pittsburgh Medical Center - Hillman Cancer Center, Pittsburgh
A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors
RecruitingPhase 1
- UPMC Hillman Cancer Center, Pittsburgh
Patient Preference for Subcutaneous vs. Intravenous Immune Therapy
RecruitingPhase 2
- UPMC Hillman Cancer Center, Pittsburgh
RP1 in Primary Melanoma to Reduce the Risk of Sentinel Lymph Node Metastasis
RecruitingEarly phase 1
- UPMC Hillman Cancer Center, Pittsburgh
A Study of VET3-TGI in Patients With Solid Tumors
RecruitingPhase 1
- UPMC- Hillman Cancer Center, Pittsburgh
A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma
RecruitingPhase 2/3
- UPMC Hillman Cancer Center, Pittsburgh
Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)
RecruitingPhase 3
- UPMC Hillman Cancer Center, Pittsburgh
Effects of Anti-PD1 Adjuvant Checkpoint Blockade Immunotherapy on Atypical/Dysplastic Nevi
RecruitingObservational study
- UPMC Hillman Cancer Center, Pittsburgh
Phase 1/2 Study of Intratumoral Injection of STX-001 in Advanced Solid Tumors as Monotherapy or in Combination With Pembrolizumab
RecruitingPhase 1/2
- University of Pittsburgh Medical Center, Pittsburgh
A Clinical Study of Intratumoral MVR-T3011 (T3011) Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors
RecruitingPhase 1/2
- University of Pittsburgh Medical Center, Pittsburgh
A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors
RecruitingPhase 1/2
- UPMC Hillman Cancer Center, Pittsburgh
Safety, Tolerability, and Preliminary Efficacy of CJRB-101 With Pembrolizumab in Subjects With Selected Types of Advanced or Metastatic Cancer
RecruitingPhase 1/2
- University of Pittsburgh, Pittsburgh
About Melanoma
Melanoma is the most serious type of skin cancer. Most have a black or black-blue area. Learn the 'ABCDE' of what to watch for and treatment options.
More about Melanoma on MedlinePlus
Melanoma trials in other cities
- Houston, TX59 studies
- New York City, NY38 studies
- Los Angeles, CA34 studies
- Nashville, TN33 studies
- Boston, MA26 studies
- Philadelphia, PA23 studies
- San Francisco, CA22 studies
- Durham, NC21 studies
- Atlanta, GA21 studies
- St. Louis, MO21 studies
- Salt Lake City, UT21 studies
- Columbus, OH21 studies
Other studies in Pittsburgh
- Non-Small Cell Lung Cancer48 studies
- Cancer (all types)41 studies
- Breast Cancer39 studies
- Colorectal Cancer32 studies
- Metastatic Cancer31 studies
- Ovarian Cancer30 studies
- Endometrial Cancer23 studies
- Lung Cancer23 studies
- Prostate Cancer23 studies
- Stroke22 studies
- Head and Neck Squamous Cell Carcinoma22 studies
- Depression22 studies
From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.