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Sickle Cell Disease clinical trials in Washington, DC

20 studies for Sickle Cell Disease are looking for participants at sites in and around Washington (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants

RecruitingObservational studyHealthy volunteers welcome
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
Ages 18 to 70 · All sexes · Updated Oct 2, 2026 · NCT03937817

Blood Sampling for Research Related to Sickle Cell Disease

RecruitingObservational studyHealthy volunteers welcome
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
Ages 18 to 100 · All sexes · Updated Sep 29, 2026 · NCT00542230

Determination of Red Cell Survival in Sickle Cell Disease and Other Hemoglobinopathies Using Biotin Labeling

RecruitingEarly phase 1
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
Ages 18 to 100 · All sexes · Updated Sep 28, 2026 · NCT06313398

Dietary Intake and Dietary Behaviors in Adults With Sickle Cell Disease

RecruitingObservational study
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
Ages 18 to 120 · All sexes · Updated Sep 18, 2026 · NCT05170412

Study to Evaluate the Safety and Tolerability of Escalating Doses of Fostamatinib in Subjects With Stable Sickle Cell Disease

RecruitingPhase 1
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
Ages 18 to 65 · All sexes · Updated Sep 17, 2026 · NCT05904093

A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease

RecruitingPhase 3
  • Childrens National Medical Ctr, Washington D.C.
  • MedStar Hlth Res Institute, Washington D.C.
Ages 12 and older · All sexes · Updated Sep 17, 2026 · NCT06612268

Study to Understand the Genetic Risk of Developing an Immune Response After Blood Transfusions Among Individuals With Sickle Cell Disease

RecruitingObservational study
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
Ages 2 to 99 · All sexes · Updated Sep 11, 2026 · NCT06944067

SCD Stem Cell Mobilization and Apheresis Using Motixafortide

RecruitingPhase 1
  • National Heart, Blood and Lung Institute-Cellular and Molecular Therapy Branch, Bethesda · 7 mi away
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06442761

Partial Stem Cell Transplant for Sickle Cell Disease From Matched Donors

RecruitingPhase 1/2
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
Ages 4 to 65 · All sexes · Updated Sep 4, 2026 · NCT07599176

Escalating Doses of VAS-101 in Subjects With Stable Sickle Cell Disease

RecruitingPhase 1
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
Ages 18 to 90 · All sexes · Updated Aug 24, 2026 · NCT07566494

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

RecruitingObservational study
  • Georgetown University, Washington D.C.
  • Children's National Hemophilia Center, Washington D.C.
All ages · All sexes · Updated Aug 17, 2026 · NCT04398628

Safety of Anumigilimab (CSL324) in Adults With Sickle Cell Disease (SCD)

RecruitingPhase 2
  • Center for Cancer and Blood Disorders, Bethesda · 7 mi away
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT07224360

Cooperative Assessment of Late Effects for SCD Curative Therapies

RecruitingObservational study
  • Children's National Medical Center, Washington D.C.
  • National Institutes of Health Clinical Center, Bethesda · 7 mi away
Ages 4 to 65 · All sexes · Updated Jul 27, 2026 · NCT05153967

Comparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell Disease

RecruitingObservational study
  • Children's National Hospital (MRD-HCT), Washington D.C.
Ages 3 to 20 · All sexes · Updated Jun 4, 2026 · NCT06941389

Intravenous L-Citrulline for Vaso-occlusive Pain Episode in Sickle Cell Disease

RecruitingPhase 2
  • Children's National Hospital, Washington D.C.
Ages 4 to 21 · All sexes · Updated Apr 13, 2026 · NCT06635902

Minimizing Toxicity in HLA-identical Sibling Donor Transplantation for Children With Sickle Cell Disease

RecruitingPhase 2
  • Children's National Health System, Washington D.C.
Ages 2 to 25 · All sexes · Updated Mar 10, 2026 · NCT03587272

Sickle Cell Disease Transplant Using a Nonmyeloablative Approach for Patients With Anti-donor Red Cell Antibody

RecruitingPhase 2
  • Children's National Hospital, Washington D.C.
Ages 2 to 25 · All sexes · Updated Sep 26, 2025 · NCT06358638

Advancing Feasibility and Acceptability of Digital Cognitive Rehabilitation in Sickle Cell Disease

Recruiting
  • Children's National Hospital, Washington D.C.
Ages 7 to 16 · All sexes · Updated Feb 13, 2025 · NCT06770010

Feasibility and Efficacy of Attentional-Control Training in Sickle Cell Disease

Recruiting
  • Children's National Hospital, Washington D.C.
Ages 8 to 16 · All sexes · Updated Jan 10, 2025 · NCT05099874

About Sickle Cell Disease

Sickle cell disease is a group of inherited disorders that affect your red blood cells. It can cause pain, anemia, and other problems. Learn about treatments.

More about Sickle Cell Disease on MedlinePlus

Sickle Cell Disease trials in other cities

Other studies in Washington

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.