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Breast Cancer clinical trials in San Diego, CA
41 studies for Breast Cancer are looking for participants at sites in and around San Diego (within about 30 miles). Open a study to see who can join and how to contact the study team.
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Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer
RecruitingPhase 3
- University of California San Diego Moores Cancer Center, San Diego
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
RecruitingPhase 1/2
- University of San Diego Moores Cancer Center, La Jolla · 11 mi away
Phase IIIb Study of Ribociclib + ET in Early Breast Cancer
RecruitingPhase 3
- Sharp Rees Stealy Medical Group Inc, San Diego
Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors
RecruitingPhase 1
- University of California San Diego Moores Cancer Center, San Diego
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
RecruitingPhase 1/2
- Sharp Memorial Hospital, San Diego
Phase II Protocol of Proton Therapy for Partial Breast Irradiation in Early Stage Breast Cancer
RecruitingPhase 2
- California Protons Cancer Therapy Center, San Diego
Conventionally Fractionated vs. Hypofractionated Comprehensive Nodal Irradiation for Breast Cancer Using Pencil Beam Scanning Proton Therapy
RecruitingPhase 3
- California Protons Cancer Therapy Center, San Diego
ASPEN-09-03: A Study of Evorpacept in Combination With Trastuzumab and Chemotherapy in Metastatic HER2-Positive Breast Cancer
RecruitingPhase 2
- UC San Diego Moores Cancer Center, La Jolla · 11 mi away
Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer
RecruitingPhase 3
- Clinical Trial Site, La Jolla · 11 mi away
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
RecruitingPhase 3
- Moores Cancer Center, La Jolla · 11 mi away
Women Informed to Screen Depending on Measures of Risk (Wisdom Study)
RecruitingHealthy volunteers welcome
- University of California San Diego, San Diego
ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer
RecruitingPhase 3
- University Of California - San Diego Moores Cancer Center, La Jolla · 11 mi away
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
RecruitingPhase 3
- UC San Diego Moores Cancer Center, La Jolla · 11 mi away
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer
RecruitingPhase 1/2
- University of California San Diego (UCSD) - Koman Family Outpatient Pavilion ? La Jolla, La Jolla · 11 mi away
Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors
RecruitingPhase 1
- Scripps Health, San Diego
A Phase 1/1b Study of IAM1363 in HER2 Cancers
RecruitingPhase 1
- UCSD Moores Cancer Center, La Jolla · 11 mi away
A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer
RecruitingPhase 1/2
- University of California San Diego Medical Center, San Diego
- UC San Diego Moores Cancer Center, La Jolla · 11 mi away
A Study of Sofe-M in Participants With Selected Advanced Solid Tumors
RecruitingPhase 1
- University of California, San Diego (UCSD) - Moores Cancer Center, La Jolla · 11 mi away
Study of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid Tumors
RecruitingPhase 1/2
- University of California-San Diego, La Jolla · 11 mi away
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
RecruitingPhase 3
- Scripps Health, La Jolla · 11 mi away
Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.
RecruitingPhase 3
- UC San Diego, San Diego
FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors
RecruitingPhase 1
- UC San Diego Moores Cancer Center, La Jolla · 11 mi away
Improving Survival for Metastatic Lobular Breast Cancer (PLUMB Registry)
RecruitingObservational study
- University of California, San Diego, San Diego
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
RecruitingPhase 3
- Kaiser Permanente-Rio San Diego, San Diego
- Kaiser Permanente-San Diego Zion, San Diego
A Multi-Modality Surveillance Program for Women at High Risk for Breast Cancer
RecruitingHealthy volunteers welcome
- University of California, San Diego, La Jolla · 11 mi away
A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors
RecruitingPhase 1
- UC San Diego Moores Cancer Center, La Jolla · 11 mi away
A Pivotal Phase II Clinical Trial of Utidelone Injection Plus Capecitabine in HER2-negative Breast Cancer Patients With Brain Metastases
RecruitingPhase 2
- Scripps Health, San Diego
Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial
RecruitingPhase 3
- UC San Diego Medical Center - Hillcrest, San Diego
- California Protons Cancer Therapy Center, San Diego
- UC San Diego Moores Cancer Center, La Jolla · 11 mi away
FIH Study of RGT-419B Alone and With Endocrine Therapy in HR-Positive, HER2-Negative Advanced/Metastatic Breast Cancer
RecruitingPhase 1
- University of California, San Diego, La Jolla · 11 mi away
Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects
RecruitingPhase 3
- University of California San Diego - Moores Cancer Center, La Jolla · 11 mi away
E-Mindfulness Approaches for Living After Breast Cancer
RecruitingPhase 3
- Kaiser Permanente-San Diego Zion, San Diego
Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)
RecruitingPhase 1/2
- University of California, San Diego; Moores Cancer Center, San Diego
Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors
RecruitingPhase 1
- Investigative Site #101, La Jolla · 11 mi away
I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer
RecruitingPhase 2
- University of California San Diego, La Jolla · 11 mi away
Evexomostat Plus PI3K or AKT Inhibitor and Fulvestrant in Patients With a PI3K Alteration and HR+/Her2- Breast Cancer
RecruitingPhase 1/2
- SHARP Healthcare, San Diego
Artificial Intelligence and Machine Learning to Guide CDK4/6 Inhibitor Rechallenge in Breast Cancer.
RecruitingPhase 2
- University of California, San Diego, La Jolla · 11 mi away
A Phase 1/2 Clinical Trial to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of HMBD-501 in Patients With HER3-Expressing Solid Tumors
RecruitingPhase 1/2
- Research Site, La Jolla · 11 mi away
Confirmatory Clinical Evaluation of Novilase® Laser Therapy for Focal Destruction of Malignant Breast Tumors
Recruiting
- UC San Diego Health, La Jolla · 11 mi away
Efficacy of OneMark Device in Identifying Breast Cancer for Surgery and Surveillance
Recruiting
- University of California, San Diego, La Jolla · 11 mi away
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
RecruitingObservational study
- Massive Bio SYNERGY-AI site, La Jolla · 11 mi away
First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer
RecruitingPhase 1
- University of California-San Diego, San Diego
About Breast Cancer
Breast cancer is a cancer that starts in the breast tissue, when cells change and grow out of control. These extra cells can form a mass called a tumor.
More about Breast Cancer on MedlinePlus
Breast Cancer trials in other cities
- New York City, NY136 studies
- Houston, TX126 studies
- Boston, MA112 studies
- Nashville, TN81 studies
- Los Angeles, CA73 studies
- Edison, NJ68 studies
- St. Louis, MO64 studies
- Queens, NY64 studies
- Durham, NC64 studies
- Chicago, IL59 studies
- Philadelphia, PA56 studies
- Dallas, TX55 studies
Other studies in San Diego
- Non-Small Cell Lung Cancer48 studies
- Cancer (all types)32 studies
- Prostate Cancer31 studies
- Metastatic Cancer30 studies
- Colorectal Cancer25 studies
- Ovarian Cancer24 studies
- Pancreatic Cancer24 studies
- Lung Cancer23 studies
- Obesity23 studies
- Heart Failure23 studies
- Depression21 studies
- Melanoma18 studies
From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.