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Head and Neck Squamous Cell Carcinoma clinical trials in Jacksonville, FL

12 studies for Head and Neck Squamous Cell Carcinoma are looking for participants at sites in and around Jacksonville (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program

RecruitingPhase 2
  • Mayo Clinic in Florida, Jacksonville
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06265285

FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC

RecruitingPhase 2/3
  • Site #0148, Jacksonville
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06788990

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #78, Jacksonville
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

RecruitingPhase 1
  • Research Site, Jacksonville
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT05877599

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

RecruitingPhase 2
  • Mayo Clinic in Florida, Jacksonville
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05136196

JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC

RecruitingPhase 3
  • Mayo Clinic Jacksonville, Jacksonville
Ages 60 and older · All sexes · Updated Sep 25, 2026 · NCT04892173

A Study of JNJ-90301900 in Combination With Chemoradiation Therapy in Participants With Locally Advanced Head and Neck Squamous Cell Carcinoma

RecruitingPhase 1
  • Mayo Clinic, Jacksonville
Ages 18 to 74 · All sexes · Updated Sep 25, 2026 · NCT07219212

A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)

RecruitingObservational study
  • Mayo Clinic Florida, Jacksonville
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06163534

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

RecruitingPhase 1/2
  • Mayo Clinic in Florida, Jacksonville
Ages 16 and older · All sexes · Updated Aug 20, 2026 · NCT05269381

Risk Adapted De-Intensification of Radio-Chemotherapy for Oropharyngeal Squamous Cell Carcinoma

RecruitingPhase 2
  • UF Health Proton Therapy Institute, Jacksonville
Ages 18 and older · All sexes · Updated Apr 24, 2026 · NCT05268614

A Study of SPX-303, a Bispecific Antibody Targeting LILRB2 and PD-L1 in Patients With Solid Tumors

RecruitingPhase 1
  • Mayo Clinic Florida, Jacksonville
Ages 18 and older · All sexes · Updated Sep 24, 2024 · NCT06259552

Head and Neck Squamous Cell Carcinoma trials in other cities

Other studies in Jacksonville

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.