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Obesity clinical trials in Jacksonville, FL

25 studies for Obesity are looking for participants at sites in and around Jacksonville (within about 30 miles). Open a study to see who can join and how to contact the study team.

Study of Olatorepatide in Adult Participants Living With Overweight or Obesity Without Diabetes

RecruitingPhase 2
  • Flourish Research, Jacksonville Center for Clinical Research, Jacksonville
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07685808

Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities

RecruitingPhase 2
  • Encore Research Group-Jacksonville Center for Clinical Research /ID# 282740, Jacksonville
Ages 18 to 75 · All sexes · Updated Sep 29, 2026 · NCT07752979

AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose Weight

RecruitingPhase 3
  • Jacksonville Ctr Clin Res, Jacksonville
  • Northeast Research Institute, Fleming Island · 17 mi away
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07720271

A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide

RecruitingPhase 3
  • Jacksonville Ctr Clin Res, Jacksonville
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07668414

A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus

RecruitingPhase 3
  • Research Site, Jacksonville
  • Research Site, Jacksonville
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07776509

A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin

RecruitingPhase 3
  • Jacksonville Center for Clinical Research, Jacksonville
  • Northeast Research Institute (NERI), Fleming Island · 17 mi away
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07392190

A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight

RecruitingPhase 3
  • Research Site, Fleming Island · 17 mi away
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07784270

Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight

RecruitingPhase 3
  • Westside Center for Clinical Research, Jacksonville
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07353931

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

RecruitingPhase 3
  • East Coast Institute for Research, LLC, Jacksonville
Ages 45 to 99 · All sexes · Updated Sep 22, 2026 · NCT07037433

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes

RecruitingPhase 3
  • Jacksonville Center for Clinical Research, Jacksonville
  • Fleming Island Center for Clinical Research, Fleming Island · 17 mi away
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07282600

Effects of Glucagon-like Peptide-1 (GLP-1) Agonist in Neuro-reproductive Function in Obese Adolescent Females With Polycystic Ovary Syndrome (PCOS)

RecruitingObservational study
  • Nemours Children's Clinic, Jacksonville
Ages 12 to 18 · Women · Updated Sep 18, 2026 · NCT07169136

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities

RecruitingPhase 3
  • AURORA-1 Clinical Site, Jacksonville
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07743463

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes

RecruitingPhase 3
  • AURORA-2 Clinical Site, Jacksonville
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07743450

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

RecruitingPhase 3
  • East Coast Institute for Research, Jacksonville
  • First Coast Cardiovascular Institute PA, Jacksonville
  • Jacksonville Center for Clinical Research, Jacksonville
Ages 18 to 99 · All sexes · Updated Sep 16, 2026 · NCT07037459

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

RecruitingPhase 3Healthy volunteers welcome
  • ACCOMPLISH-2 Research Site, Jacksonville
Ages 18 to 79 · All sexes · Updated Sep 11, 2026 · NCT07654374

AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

RecruitingPhase 3
  • Jacksonville Ctr Clin Res, Jacksonville
  • Northeast Research Institute, Fleming Island · 17 mi away
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07533175

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)

RecruitingPhase 3
  • Jacksonville Center for Clinical Research, Jacksonville
  • Clinical Neuroscience Solutions - Jacksonville, Jacksonville
Ages 18 to 99 · All sexes · Updated Sep 3, 2026 · NCT07684235

A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight

RecruitingPhase 3
  • Jacksonville Ctr for Clin Res, Jacksonville
Ages 8 to 18 · All sexes · Updated Aug 31, 2026 · NCT07253285

A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus

RecruitingPhase 3
  • Research Site, Jacksonville
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT07784725

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

RecruitingPhase 3
  • Jacksonville Ctr for Clin Res, Jacksonville
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07567001

The Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in Post-menopausal Women With Obesity

RecruitingPhase 4Healthy volunteers welcome
  • Mayo Clinic in Florida, Jacksonville
Ages 46 to 60 · Women · Updated Aug 18, 2026 · NCT07218445

AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain

RecruitingPhase 3
  • Westside Center For Clinical Research, Jacksonville
  • Clinical Neuroscience Solutions, LLC, Jacksonville
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT07509307

A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain

RecruitingPhase 3
  • CNS Healthcare, Jacksonville
Ages 18 and older · All sexes · Updated Jul 9, 2026 · NCT07481630

Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse Events

RecruitingPhase 1
  • Jacksonville Ctr For Clin Res, Jacksonville
  • Northeast Research Institute, Fleming Island · 17 mi away
Ages 18 and older · All sexes · Updated Jun 25, 2026 · NCT07607587

Knee Injections for Obese Patients With Knee Arthritis

RecruitingPhase 4
  • Mayo Clinic in Florida, Jacksonville
Ages 55 to 85 · All sexes · Updated Mar 10, 2026 · NCT06782529

About Obesity

Read about the causes of obesity and find out what you can do to decrease your risk of its associated health issues.

More about Obesity on MedlinePlus

Obesity trials in other cities

Other studies in Jacksonville

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.