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Heart Diseases clinical trials in Los Angeles, CA

12 studies for Heart Diseases are looking for participants at sites in and around Los Angeles (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Transition to KPL-387 Monotherapy Dosing & Administration Study

RecruitingPhase 2
  • Investigational Site 014, Los Angeles
Ages 18 to 80 · All sexes · Updated Sep 30, 2026 · NCT07288216

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

Recruiting
  • PIH Health Good Samaritan Hospital, Los Angeles
  • Kaiser Permanente Los Angeles Medical Center, Los Angeles
  • Keck Hospital of the University of Southern California, USC, Los Angeles
  • and 1 more
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT03242642

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

Recruiting
  • Cedars-Sinai Medical Center, Los Angeles
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031

Abbott Structural Heart Device Registry

RecruitingObservational study
  • USC University Hospital, Los Angeles
All ages · All sexes · Updated Sep 1, 2026 · NCT06590467

Reduction or Elimination of Mitral Regurgitation With the SATURN TMVR System (CASSINI-US)

Recruiting
  • Cedars-Sinai Medical Center, Los Angeles
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT07130994

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

RecruitingPhase 3
  • University of California, Los Angeles (UCLA) - David Geffen School of Medicine, Los Angeles
Ages 18 to 75 · All sexes · Updated Aug 4, 2026 · NCT06563895

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

Recruiting
  • USC, Los Angeles
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

Recruiting
  • Keck School of Medicine of USC, Los Angeles
  • UCLA Medical Center, Los Angeles
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152

Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women

Recruiting
  • Cedars-Sinai Medical Center, Los Angeles
Ages 18 and older · Women · Updated Apr 1, 2026 · NCT04124120

Focused Orticumab Research for Treating Inflammation in Coronary Arteries

RecruitingPhase 2
  • Abcentra Investigational Site, Los Angeles
Ages 18 and older · All sexes · Updated Jan 27, 2026 · NCT06927739

PARTNER 3 Trial - Aortic Valve-in-Valve

Recruiting
  • University of California Los Angeles, Los Angeles
All ages · All sexes · Updated May 10, 2024 · NCT03003299

Heart Disease of the Small Arteries in Women and Men

Recruiting
  • Cedars-Sinai Women's Heart Center, Los Angeles
Ages 18 and older · All sexes · Updated Sep 1, 2023 · NCT00573027

About Heart Diseases

Heart disease is the leading cause of death in the U.S. Learn about the different types of heart diseases, and what you can do to try to prevent them.

More about Heart Diseases on MedlinePlus

Heart Diseases trials in other cities

Other studies in Los Angeles

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.