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Parkinson's Disease clinical trials in Cleveland, OH

18 studies for Parkinson's Disease are looking for participants at sites in and around Cleveland (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Study to Determine if BHV-8000 is Effective, Safe and Tolerable as a Treatment for Adults Living With Early Parkinson's Disease

RecruitingPhase 2/3
  • Site-082, Cleveland
Ages 40 to 80 · All sexes · Updated Sep 28, 2026 · NCT06976268

A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations

RecruitingPhase 2
  • Cleveland Clinic (Site #223), Cleveland
Ages 30 to 80 · All sexes · Updated Sep 10, 2026 · NCT07432958

Parkinson's Foundation PD GENEration Genetic Registry

RecruitingObservational study
  • Case Western Reserve University, Cleveland
  • Cleveland Clinic, Cleveland
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT04994015

A US Study That Observes How Parkinson's Disease Changes Over Time in Patients Who Still Have Movement Symptoms Despite Taking Parkinson's Medications

RecruitingObservational study
  • Cleveland Clinic, Cleveland
Ages 45 to 75 · All sexes · Updated Sep 4, 2026 · NCT07330258

A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

RecruitingPhase 3
  • Cleveland Clinic, Cleveland
Ages 50 to 85 · All sexes · Updated Sep 3, 2026 · NCT07174310

Deep Brain Stimulation Neural Recordings of Varied Stimulation During Sleep in Parkinson's Disease

Recruiting
  • Cleveland Clinic, Cleveland
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT07110376

Genetics and Aerobic Exercise to Slow Parkinson's Disease Trial

Recruiting
  • The Cleveland Clinic, Cleveland
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT06442033

Personalized Real-Time DBS and PD Mechanisms

RecruitingPhase 4
  • Cleveland Clinic, Cleveland
Ages 18 to 80 · All sexes · Updated Aug 20, 2026 · NCT06013956

Neural Mechanisms of Aerobic Exercise Benefits in PD With DBS

RecruitingPhase 2
  • Cleveland Clinic, Cleveland
Ages 18 and older · All sexes · Updated Jul 28, 2026 · NCT07442747

PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

RecruitingObservational studyHealthy volunteers welcome
  • Cleveland Clinic, Cleveland
Ages 30 and older · All sexes · Updated Jul 27, 2026 · NCT04477785

Optimizing Deep Brain Stimulation to Improve Visuomotor Function in Parkinson's Disease

RecruitingObservational study
  • Louis Stokes VA Medical Center, Cleveland, OH, Cleveland
All ages · All sexes · Updated Jul 7, 2026 · NCT06857851

BOOST-PD A Naturalistic Study on IPX-203 for Parkinson's Disease

RecruitingPhase 4
  • Cleveland Clinic, Cleveland
Ages 40 and older · All sexes · Updated Jun 23, 2026 · NCT07138560

Steady Together Fall Prevention Program in the Home

Recruiting
  • InMotion Wellness Center, Beachwood · 10 mi away
Ages 18 and older · All sexes · Updated Apr 9, 2026 · NCT07519096

Black and African Americans Connections to Parkinson's Disease (BLAAC PD)

RecruitingObservational studyHealthy volunteers welcome
  • University Hospitals Cleveland Medical Center, Cleveland
Ages 18 and older · All sexes · Updated Feb 27, 2026 · NCT06719583

Virtual tES Device Treatment for Parkinson's Disease Motor Symptoms

RecruitingPhase 1/2
  • U LLC Headquarters, Cleveland
Ages 18 to 80 · All sexes · Updated Jan 27, 2026 · NCT07182058

Abbott DBS Post-Market Study of Outcomes for Indications Over Time

RecruitingObservational study
  • The Cleveland Clinic Foundation, Cleveland
All ages · All sexes · Updated Jan 8, 2026 · NCT04071847

Deep Brain Stimulation for Visuomotor Function in Parkinson's Disease

RecruitingObservational study
  • Louis Stokes VA Medical Center, Cleveland, OH, Cleveland
All ages · All sexes · Updated Jan 7, 2026 · NCT05400499

A Study of CREXONT (Carbidopa and Levodopa) Extended-Release Capsules in Participants With Parkinson's Disease

RecruitingPhase 4
  • University Hospitals Cleveland Medical Center, Cleveland
Ages 18 and older · All sexes · Updated Aug 24, 2025 · NCT06765668

About Parkinson's Disease

Parkinson's disease (PD) is a movement disorder. It causes tremors, stiffness, and slow movement. It gets worse over time. Learn what can help.

More about Parkinson's Disease on MedlinePlus

Parkinson's Disease trials in other cities

Other studies in Cleveland

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.