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Seizures clinical trials in Philadelphia, PA

11 studies for Seizures are looking for participants at sites in and around Philadelphia (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

An Efficacy and Safety Study of Clemizole HCl in Patients With Lennox-Gastaut Syndrome

RecruitingPhase 3
  • Children's Hospital of Philadelphia, Philadelphia
Ages 2 to 55 · All sexes · Updated Oct 2, 2026 · NCT05066217

RENAISSANCE 2: SPN-817 Phase 2, Double-Blind, Placebo-Controlled Study in Adults With Focal Onset Seizures

RecruitingPhase 2
  • Thomas Jefferson University, Philadelphia
Ages 18 to 70 · All sexes · Updated Oct 1, 2026 · NCT06798896

Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures FOCUS-1

RecruitingPhase 3
  • Thomas Jefferson University, Philadelphia
Ages 18 to 75 · All sexes · Updated Oct 1, 2026 · NCT07563881

Prospective Natural History Study of POLG Disease

RecruitingObservational study
  • Children's Hospital of Philadelphia-Philadelphia, Philadelphia
All ages · All sexes · Updated Sep 15, 2026 · NCT07775872

A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome

RecruitingPhase 3
  • The Children's Hospital of Philadelphia, Philadelphia
Ages 2 and older · All sexes · Updated Sep 15, 2026 · NCT04462770

A Clinical Trial of Elsunersen in Pediatric SCN2A-DEE to Assess Efficacy and Safety

RecruitingPhase 3
  • Praxis Research Site, Philadelphia
1 Day – 18 Years · All sexes · Updated Aug 3, 2026 · NCT07019922

Electrographic Seizure Management and Neurobehavioral Outcomes in Critically Ill Children

RecruitingObservational study
  • Children's Hospital of Philadelphia, Philadelphia
1 Month – 18 Years · All sexes · Updated Jun 29, 2026 · NCT03419260

Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))

RecruitingPhase 3
  • Thomas Jefferson University Hospital, Philadelphia
Ages 18 to 75 · All sexes · Updated Jun 9, 2026 · NCT05135091

A Long-term Study of the Safety and Effectiveness of RAP-219 in Adults With Focal Onset Seizures

RecruitingPhase 2
  • University of Pennsylvania - Department of Neurology, Philadelphia
Ages 18 to 70 · All sexes · Updated Jan 23, 2026 · NCT07219407

Investigate Efficacy and Safety of Carisbamate as Adjunctive Treatment for Seizures Associated With LGS in Children and Adults

RecruitingPhase 3
  • Children's Hospital of Philadelphia, Philadelphia
Ages 4 to 55 · All sexes · Updated Jul 24, 2025 · NCT05219617

Epilepsy Learning Healthcare System (ELHS)

RecruitingObservational study
  • Children's Hospital of Philadelphia (CHOP), Philadelphia
All ages · All sexes · Updated Aug 30, 2024 · NCT06265103

About Seizures

Seizures are caused by sudden, abnormal electrical activity in the brain. They can be mild or severe. Learn about the types, causes, and treatments.

More about Seizures on MedlinePlus

Seizures trials in other cities

Other studies in Philadelphia

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.