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Diffuse Large B-Cell Lymphoma clinical trials in Philadelphia, PA

15 studies for Diffuse Large B-Cell Lymphoma are looking for participants at sites in and around Philadelphia (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL

RecruitingPhase 2
  • Fox Chase Cancer Center, Philadelphia
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06500273

Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

RecruitingObservational study
  • Children's Hospital of Philadelphia, Philadelphia
Ages 0 to 38 · All sexes · Updated Oct 1, 2026 · NCT06131801

Testing the Effectiveness of a Combination Targeted Therapy (ViPOR) for Patients With Relapsed and/or Refractory Aggressive B-cell Lymphoma

RecruitingPhase 2
  • Thomas Jefferson University Hospital, Philadelphia
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06649812

A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)

RecruitingPhase 2/3
  • Alliance Cancer Specialists (ACS) ( Site 8001), Horsham · 16 mi away
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05139017

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

RecruitingPhase 2
  • Abramson Cancer Center and Perelman Center for Advanced Medicine ( Site 0131), Philadelphia
  • Temple University Hospital ( Site 0133), Philadelphia
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06890884

A Study of LY4152199 in Participants With Previously Treated B-cell Malignancies (BAF_FRontier-1 )

RecruitingPhase 1
  • University of Pennsylvania Abramson Cancer Center, Philadelphia
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07101328

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

RecruitingPhase 1/2
  • Children's Hospital of Philadelphia (CHOP) ( Site 1021), Philadelphia
6 Months – 25 Years · All sexes · Updated Sep 17, 2026 · NCT06395103

Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphoma

RecruitingPhase 1/2
  • Thomas Jefferson University, Philadelphia
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT05826535

A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas

RecruitingPhase 1/2
  • Abramson Cancer Center of the University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT04104776

Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma

RecruitingPhase 1
  • University of Pennsylvania / Abramson Cancer Center, Philadelphia
Ages 18 and older · All sexes · Updated Jul 10, 2026 · NCT05077527

A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

RecruitingPhase 1
  • University of Pennsylvania, Abramson Cancer Center, Philadelphia
Ages 18 and older · All sexes · Updated Jul 2, 2026 · NCT05131022

Radiation, Oral Vancomycin, and CAR-T for B-Cell Lymphomas

RecruitingPhase 1
  • Abramson Cancer Center, University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Jul 1, 2026 · NCT07478848

Epcoritamab-CAR T Cells for Large B-cell Lymphomas

RecruitingPhase 2
  • Abramson Cancer Center at the University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated May 27, 2026 · NCT06458439

SynKIR-310 for Relapsed/Refractory B-NHL

RecruitingPhase 1
  • Abramson Cancer Center of the University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Apr 14, 2026 · NCT06544265

Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

RecruitingPhase 2
  • University of Pennsylvania/Abramson Cancer Center, Philadelphia
Ages 18 and older · All sexes · Updated Feb 2, 2026 · NCT05633615

Diffuse Large B-Cell Lymphoma trials in other cities

Other studies in Philadelphia

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.