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Epilepsy clinical trials in Durham, NC

8 studies for Epilepsy are looking for participants at sites in and around Durham (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Diagnosing Epilepsy To EffeCT Change Long-Term Follow-Up

RecruitingObservational study
  • Duke University, Durham
Ages 18 to 75 · All sexes · Updated Sep 15, 2026 · NCT07110454

Diagnosing Epilepsy To EffeCT Change

Recruiting
  • Duke University, Durham
Ages 18 to 75 · All sexes · Updated Sep 15, 2026 · NCT07110337

A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures

RecruitingPhase 3
  • Duke University Clinical Research, Durham
Ages 12 and older · All sexes · Updated Aug 10, 2026 · NCT05667142

Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))

RecruitingPhase 3
  • Duke University Hospital, Durham
Ages 18 to 75 · All sexes · Updated Jun 9, 2026 · NCT05135091

Sleep-Sensitive Seizure Risk Assessment With Wearable EEGs

Recruiting
  • Duke University Health System, Durham
Ages 18 and older · All sexes · Updated Jun 5, 2026 · NCT06545643

Links Between Epileptic Activity, Sleep Disruption and Mental Content During Sleep

RecruitingObservational study
  • Epilepsy Department, Duke University Hospital, Durham
Ages 18 to 55 · All sexes · Updated May 26, 2026 · NCT07605858

A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)

RecruitingPhase 3
  • Duke University Clinic, Durham
Ages 18 and older · All sexes · Updated May 14, 2026 · NCT05716100

Lemborexant Treatment of Insomnia Linked to Epilepsy

RecruitingPhase 3
  • Duke University, Durham
Ages 18 and older · All sexes · Updated Feb 13, 2025 · NCT06262594

About Epilepsy

Epilepsy is a brain disorder that causes people to have seizures. The seizures may be mild or severe. Learn about causes, diagnosis, and treatment.

More about Epilepsy on MedlinePlus

Epilepsy trials in other cities

Other studies in Durham

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.