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Cardiovascular Disease clinical trials in Charleston, SC

15 studies for Cardiovascular Disease are looking for participants at sites in and around Charleston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

ELEVATE-HFpEF Clinical Study

Recruiting
  • Medical University of South Carolina (MUSC), Charleston
Ages 40 and older · All sexes · Updated Oct 2, 2026 · NCT06678841

A Phase 1 AAV Gene Therapy Trial Evaluating Safety and Preliminary Efficacy of RP-A701 in Subjects With BAG3 Dilated Cardiomyopathy

RecruitingPhase 1
  • Medical University of South Carolina, Charleston
Ages 18 to 65 · All sexes · Updated Oct 1, 2026 · NCT07137338

Product Surveillance Registry

RecruitingObservational study
  • Charleston, Charleston
All ages · All sexes · Updated Sep 18, 2026 · NCT01524276

Zenith® Fenestrated+ Clinical Study

Recruiting
  • Medical University of South Carolina, Charleston
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT04875429

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

Recruiting
  • Medical University of South Carolina, Charleston
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031

A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD

RecruitingPhase 2
  • Clinical Research Site, Charleston
Ages 18 to 85 · All sexes · Updated Sep 2, 2026 · NCT07333183

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

RecruitingPhase 4Healthy volunteers welcome
  • Charleston VA Medical Center, Charleston
  • Medical University of South Carolina, Charleston
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

RecruitingPhase 3
  • Research Site, Charleston
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT07000357

OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

RecruitingPhase 3
  • Pharmacorp Clinical Trials Inc, Charleston
  • Medical University of South Carolina, Charleston
Ages 50 to 105 · All sexes · Updated Aug 21, 2026 · NCT07136012

Global Paradise System US Post Approval Study

RecruitingObservational study
  • Medical University of South Carolina, Charleston
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT06297291

Behavioral Activation Delivered Via Home-based Telehealth to Improve Functioning in Cardiovascular Disease Patients Recently Discharged From Inpatient Care

Recruiting
  • Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston
Ages 21 and older · All sexes · Updated Jul 27, 2026 · NCT04877197

The TRICURE EFS Study

Recruiting
  • Medical University of South Carolina, Charleston
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT06506942

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

Recruiting
  • Medical University of South Carolina (MUSC), Charleston
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

Recruiting
  • Medical University of South Carolina, Charleston
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195

Pivotal Study for the Cardiac Performance System (CPS)

RecruitingObservational study
  • Medical University of South Carolina, Charleston
Ages 18 and older · All sexes · Updated Apr 24, 2026 · NCT06870591

Cardiovascular Disease trials in other cities

Other studies in Charleston

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.