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Obesity clinical trials in Louisville, KY

17 studies for Obesity are looking for participants at sites in and around Louisville (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)

RecruitingPhase 3
  • Louisville Metabolic and Atherosclerosis Research Center, Louisville
Ages 18 to 99 · All sexes · Updated Oct 5, 2026 · NCT07684235

Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities

RecruitingPhase 2
  • L-MARC Research Center /ID# 282008, Louisville
Ages 18 to 75 · All sexes · Updated Oct 2, 2026 · NCT07752979

A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity

RecruitingPhase 3
  • Monroe Biomedical Research, Louisville
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07595549

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

RecruitingPhase 3
  • Gastroenterology Health Partners, Louisville
  • Gastroenterology Health Partners, New Albany · 4 mi away
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937099

A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

RecruitingPhase 3
  • Norton Children's Endocrinology, Louisville
Ages 6 to 17 · All sexes · Updated Sep 24, 2026 · NCT06672549

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

RecruitingPhase 3
  • Gastroenterology Health Partners, Louisville
  • Gastroenterology Health Partners, New Albany · 4 mi away
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937086

Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight

RecruitingPhase 3
  • Monroe Biomedical Research - Louisville, Louisville
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07353931

A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight

RecruitingPhase 2
  • Monroe Biomedical Research - Louisville, Louisville
Ages 18 to 75 · All sexes · Updated Sep 22, 2026 · NCT07589608

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes

RecruitingPhase 3
  • Monroe Biomedical Research, Louisville
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07351045

Research Study on How Well Oral Semaglutide Works for Weight Loss in Adults With Excess Body Weight

RecruitingPhase 3
  • L-MARC Research Center, Louisville
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07770841

A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight

RecruitingPhase 2
  • Monroe Biomedical Research - Louisville, Louisville
Ages 18 to 75 · All sexes · Updated Sep 8, 2026 · NCT06143956

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

RecruitingPhase 3
  • UofL Health Care Outpatient, Louisville
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07567001

AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain

RecruitingPhase 3
  • Monroe Biomedical Research, LLC, Louisville
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT07509307

Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)

RecruitingPhase 3
  • ACCOMPLISH-1 Research Site, Louisville
Ages 18 to 79 · All sexes · Updated Aug 10, 2026 · NCT07654361

A Study to See How Safe and Effective Alirocumab is When Given Weekly to Adult Participants Who Have Hypercholesterolemia

RecruitingPhase 2
  • L-MARC Research Center, Louisville
Ages 18 to 80 · All sexes · Updated Jul 22, 2026 · NCT07477704

A Phase 2A Clinical Trial to Assess the Safety and Tolerability of ERX1000 in Men and Women for the Treatment of Obesity.

RecruitingPhase 2
  • Monroe Biomedical Research, Louisville
Ages 18 to 60 · All sexes · Updated Jun 22, 2026 · NCT07570758

Adrenergic Cholinergic Enteric Measures/Mapping

RecruitingObservational study
  • University of Louisville, Louisville
Ages 10 to 80 · All sexes · Updated Jan 10, 2025 · NCT04013282

About Obesity

Read about the causes of obesity and find out what you can do to decrease your risk of its associated health issues.

More about Obesity on MedlinePlus

Obesity trials in other cities

Other studies in Louisville

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.