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Obesity clinical trials in Houston, TX

44 studies for Obesity are looking for participants at sites in and around Houston (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide

RecruitingPhase 3
  • Houston Research Institute, Houston
  • The Endocrine Center, Houston
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07668414

A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity

RecruitingPhase 3
  • PlanIt Research, LLC (Monitoring Room), Houston
  • PlanIt Research, LLC, Houston
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07595549

Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities

RecruitingPhase 2
  • PlanIt Research /ID# 282204, Houston
Ages 18 to 75 · All sexes · Updated Sep 25, 2026 · NCT07752979

A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

RecruitingPhase 3
  • McGovern Medical School, Houston
  • Texas Childrens Hospital, Houston
  • Dynamed Clinical Research, LP d/b/a DM Clinical Research, Houston
  • and 1 more
Ages 6 to 17 · All sexes · Updated Sep 24, 2026 · NCT06672549

A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes

RecruitingPhase 3
  • The University of Texas Health Science Center at Houston, Bellaire · 7 mi away
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07321886

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

RecruitingPhase 3
  • Biopharma Informatic, LLC, Houston
  • Cardiovascular Specialists of Willowbrook, Houston
  • PlanIt Research, PLLC, Houston
  • and 2 more
Ages 45 to 99 · All sexes · Updated Sep 22, 2026 · NCT07037433

A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight

RecruitingPhase 3
  • Research Site, Houston
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07784270

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes

RecruitingPhase 3
  • Juno Research, Houston
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07282600

A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event

RecruitingPhase 2
  • Cardiovascular Specialists of Willowbrook, Houston
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07783802

A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin

RecruitingPhase 3
  • Juno Research, Houston
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07392190

A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight

RecruitingPhase 2
  • PlanIt Research, PLLC, Houston
Ages 18 to 75 · All sexes · Updated Sep 22, 2026 · NCT07589608

Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight

RecruitingPhase 3
  • Care Access - Houston, Houston
  • JCCT - Juno Bellaire Site, Bellaire · 7 mi away
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07353931

A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the Knee

RecruitingPhase 3
  • Juno Research, Houston
  • Biopharma Informatic, LLC, Houston
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07153471

Semaglutide for Post-Smoking Cessation Weight Management

RecruitingPhase 2Healthy volunteers welcome
  • The University of Texas Health Science Center at Houston, Houston
Ages 18 to 75 · All sexes · Updated Sep 21, 2026 · NCT06173778

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes

RecruitingPhase 3
  • AURORA-2 Clinical Site, Houston
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07743450

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

RecruitingPhase 3
  • East Texas Cardiology PA, Houston
  • Biopharma Informatic, Houston
  • Orion Medical, Houston
  • and 3 more
Ages 18 to 99 · All sexes · Updated Sep 16, 2026 · NCT07037459

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes

RecruitingPhase 3
  • Elevate Clinical, Houston
  • Houston Research Institute, Houston
  • Bellaire Clinical Research, LLC, Bellaire · 7 mi away
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07351045

A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide

RecruitingPhase 2
  • Juno Research, Houston
Ages 18 to 75 · All sexes · Updated Sep 14, 2026 · NCT06897475

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes

RecruitingPhase 3
  • HRI ? Medical Center, LLC, Houston
  • Juno Research, LLC, Houston
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07351058

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

RecruitingPhase 3Healthy volunteers welcome
  • ACCOMPLISH-2 Research Site, Houston
  • ACCOMPLISH-2 Research Site, Houston
Ages 18 to 79 · All sexes · Updated Sep 11, 2026 · NCT07654374

A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 Diabetes

RecruitingPhase 2
  • Biopharma Informatic, LLC, Houston
  • PlanIt Research, PLLC, Houston
  • Research Physicians Network, LLC, Houston
Ages 18 to 75 · All sexes · Updated Sep 8, 2026 · NCT07215559

A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight

RecruitingPhase 2
  • PlanIt Research, PLLC, Houston
Ages 18 to 75 · All sexes · Updated Sep 8, 2026 · NCT06143956

A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)

RecruitingPhase 4
  • Center for Clinical Studies, Houston
  • Bellaire Dermatology Associates, Bellaire · 7 mi away
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06857942

AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

RecruitingPhase 3
  • PlanIt Research, PLLC, Houston
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07533175

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)

RecruitingPhase 3
  • JCCT- Juno Northwest Houston, Houston
  • Biopharma Informatic, LLC, Houston
  • Johnson County Clinical Trials Juno Bellaire, Bellaire · 7 mi away
Ages 18 to 99 · All sexes · Updated Sep 3, 2026 · NCT07684235

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)

RecruitingPhase 3
  • JCCT- Juno Northwest Houston, Houston
  • Johnson County Clinical Trials Juno Bellaire, Bellaire · 7 mi away
Ages 18 to 99 · All sexes · Updated Sep 3, 2026 · NCT07684144

Efficacy and Safety of Ribupatide in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have Diabetes

RecruitingPhase 3
  • Kailera Clinical Site, Bellaire · 7 mi away
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT07284875

A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight

RecruitingPhase 3
  • DM Clinical, Houston
Ages 8 to 18 · All sexes · Updated Aug 31, 2026 · NCT07253285

Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)

RecruitingPhase 3
  • Biopharma Informatic, LLC, Houston
  • Research Physicians Network, LLC, Houston
Ages 18 to 99 · All sexes · Updated Aug 27, 2026 · NCT07575399

A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus

RecruitingPhase 3
  • Research Site, Houston
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT07784725

Caloric Restriction and Activity to Reduce Chemoresistance in B-ALL

RecruitingPhase 2
  • Baylor Texas Children's Hospital, Houston
Ages 7 to 25 · All sexes · Updated Aug 19, 2026 · NCT05082519

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

RecruitingPhase 3
  • East Texas Cardiology PA, Houston
  • Victorium Clinical Research, Houston
  • Main Heart Clinic, Houston
  • and 1 more
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07567001

Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)

RecruitingPhase 3
  • ACCOMPLISH-1 Research Site, Houston
  • ACCOMPLISH-1 Research Site, Houston
Ages 18 to 79 · All sexes · Updated Aug 10, 2026 · NCT07654361

PATHS-UP Health Behavior Self-monitoring Mobile App for Adolescents

RecruitingHealthy volunteers welcome
  • Children's Nutrition Research Center, Houston
Ages 12 to 18 · All sexes · Updated Jul 7, 2026 · NCT06959901

Adapting and Assessing the Feasibility of a Telehealth Diabetes Prevention Program for Hispanic Adolescents

RecruitingHealthy volunteers welcomeMentions payment for participants
  • USDA/ARS Children's Nutrition Research Center, Baylor College of Medicine, Houston
Ages 14 to 16 · All sexes · Updated Jul 7, 2026 · NCT06943001

Determinants of Insulin Sensitivity by Age, Sex, Race/Ethnicity, BMI, and PCOS Diagnosis

RecruitingObservational studyHealthy volunteers welcome
  • Lilli Health, Houston
Ages 18 and older · All sexes · Updated May 1, 2026 · NCT05950282

Negative Pressure Wound Therapy in Healing Abdominal Incision in Obese Patients Undergoing Breast Reconstruction Surgery

Recruiting
  • M D Anderson Cancer Center, Houston
Ages 18 and older · Women · Updated Apr 21, 2026 · NCT04003038

Incretin Microdosing for Cardiometabolic Health in People With HIV

RecruitingPhase 2
  • The University of Texas Health Science Center at Houston, Houston
Ages 18 and older · All sexes · Updated Feb 18, 2026 · NCT07325500

Metformin IN Asthma for Overweight and Obese Individuals (MINA)

RecruitingPhase 2
  • Baylor College of Medicine, Houston
Ages 18 and older · All sexes · Updated Jan 16, 2026 · NCT06273072

RESET System Pivotal Trial (Rev F)

Recruiting
  • Baylor College of Medicine, Houston
Ages 22 to 65 · All sexes · Updated Jul 18, 2024 · NCT04101669

Endoscopic Sleeve Gastroplasty (ESG) for the Treatment of Obesity

Recruiting
  • Houston Methodist Hospital, Houston
Ages 18 and older · All sexes · Updated Apr 1, 2024 · NCT06339320

About Obesity

Read about the causes of obesity and find out what you can do to decrease your risk of its associated health issues.

More about Obesity on MedlinePlus

Obesity trials in other cities

Other studies in Houston

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.