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Ovarian Cancer clinical trials in St. Louis, MO

38 studies for Ovarian Cancer are looking for participants at sites in and around St. Louis (within about 30 miles). Open a study to see who can join and how to contact the study team.

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The Vanguard Study: Testing a New Way to Screen for Cancer

RecruitingHealthy volunteers welcome
  • Washington University School of Medicine, St Louis
Ages 45 to 75 · All sexes · Updated Oct 5, 2026 · NCT06995898

Phase 3 Trial Evaluating the Safety & Efficacy of IMNN-001 Administered in Combination w/ Standard NACT & Adjuvant Chemotherapy in Newly Diagnosed Patients w/ Advanced EOC, Fallopian Tube or Primary Peritoneal Cancer

RecruitingPhase 3
  • Washington University School of Medicine in St. Louis, St Louis
Ages 18 and older · Women · Updated Oct 5, 2026 · NCT06915025

Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With Gastric Cancer Spread to the Abdominal Cavity

RecruitingPhase 2/3
  • Washington University School of Medicine, St Louis
  • Siteman Cancer Center-South County, St Louis
  • Siteman Cancer Center at Christian Hospital, St Louis
  • and 2 more
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT07001748

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

RecruitingPhase 2
  • Washington University School of Medicine, St Louis
  • Mercy Hospital South, St Louis
  • Siteman Cancer Center-South County, St Louis
  • and 6 more
All ages · All sexes · Updated Oct 5, 2026 · NCT05564377

A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Washington University Medicine, St Louis
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06270706

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

RecruitingPhase 1
  • Washington University School of Medicine in St. Louis, St Louis
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06465069

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 2
  • Washington University, School of Medicine, St Louis
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06172478

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

RecruitingObservational study
  • Washington University, St Louis
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT04981119

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

RecruitingPhase 1
  • Washington University School of Medicine in St. Louis, St Louis
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07213791

A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

RecruitingPhase 1/2
  • Washington Univ. School of Medicine, St Louis
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07109726

Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

RecruitingPhase 3
  • Mercy Hospital St. Louis - David C. Pratt Cancer Center, St Louis
Ages 18 and older · Women · Updated Sep 15, 2026 · NCT07214779

A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

RecruitingPhase 2
  • Washington University, St Louis
Ages 18 to 99 · Women · Updated Sep 15, 2026 · NCT07023627

A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies

RecruitingPhase 1/2
  • Research Site, St Louis
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT05123482

Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)

RecruitingPhase 3
  • Washington University School of Medicine, St Louis
  • Mercy Hospital St. Louis, St Louis
Ages 18 and older · Women · Updated Aug 26, 2026 · NCT05281471

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

RecruitingPhase 1/2
  • Washington University School of Medicine, St Louis
12 Months – 30 Years · All sexes · Updated Aug 25, 2026 · NCT04851119

A Phase 1 Study of LNCB74 in Advanced Solid Tumors

RecruitingPhase 1
  • Washington University, Siteman Cancer Center, St Louis
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT06774963

A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors

RecruitingPhase 1
  • Normunity Investigational Site, St Louis
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07182149

A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

Recruiting
  • Washington University School of Medicine, St Louis
  • Missouri Baptist Medical Center, St Louis
Ages 35 to 50 · Women · Updated Aug 7, 2026 · NCT04251052

Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer

RecruitingPhase 3
  • Mercy Infusion Center - Chippewa, St Louis
  • Washington University School of Medicine, St Louis
  • Mercy Hospital South, St Louis
  • and 5 more
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT06580314

IDOV-Immune for Advanced Solid Tumors

RecruitingPhase 1
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06910657

A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Washington University, St Louis
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT04657068

A Study of Raludotatug Deruxtecan (R-DXd) in Subjects With Platinum-resistant, High-grade Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

RecruitingPhase 2/3
  • Washington University School of Medicine Obstetrics and Gynecology, St Louis
Ages 18 and older · All sexes · Updated Jul 28, 2026 · NCT06161025

Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Investigative Site #110, St Louis
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT06545942

Relacorilant in Combination With Different Treatment Regimens in Patients With Gynecological Cancers

RecruitingPhase 2
  • 521, St Louis
Ages 18 and older · Women · Updated Jul 16, 2026 · NCT06906341

First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Washington University, St Louis
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT05768139

Lead-212 PSV359 Therapy for Patients With Solid Tumors

RecruitingPhase 1/2
  • Saint Louis University, St Louis
Ages 18 to 90 · All sexes · Updated Jul 6, 2026 · NCT06710756

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

RecruitingPhase 1/2
  • Washington University, St Louis
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT06051695

Study of NMS-03305293 in Adult Patients With Relapsed Ovarian Cancer

RecruitingPhase 1
  • Washington University School of Medicine in St. Louis, St Louis
Ages 18 and older · Women · Updated May 28, 2026 · NCT06930755

JAB-30355 in Patients With Advanced Solid Tumors Harboring TP53 Y220C Mutation

RecruitingPhase 1/2
  • Research site, St Louis
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT06386146

Heated Intraperitoneal Chemotherapy Followed by Niraparib for Ovarian, Primary Peritoneal and Fallopian Tube Cancer

RecruitingPhase 3
  • Washington University School of Medicine, St Louis
Ages 18 and older · Women · Updated Apr 16, 2026 · NCT05659381

A Study of Azenosertib (ZN-c3) in Patients With Ovarian Cancer

RecruitingPhase 1
  • Site 0111, St Louis
Ages 18 and older · Women · Updated Apr 7, 2026 · NCT04516447

TUBectomy With Delayed Oophorectomy in High Risk Women to Assess the Safety of Prevention

Recruiting
  • Washington University Medical Center, St Louis
Ages 25 to 50 · Women · Updated Apr 6, 2026 · NCT04294927

CATALINA-2: A Clinical Study of TORL-1-23 in Platinum-resistant Ovarian Cancer.

RecruitingPhase 2
  • Washington University, St Louis
Ages 18 and older · Women · Updated Dec 23, 2025 · NCT06690775

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, St Louis
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

About Ovarian Cancer

Ovarian cancer is a cancerous tumor that forms in the tissues of an ovary. The ovaries are a pair of female reproductive glands that make eggs and female hormones.

More about Ovarian Cancer on MedlinePlus

Ovarian Cancer trials in other cities

Other studies in St. Louis

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.