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Post-Traumatic Stress Disorder clinical trials in Boston, MA

19 studies for Post-Traumatic Stress Disorder are looking for participants at sites in and around Boston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

RISE Versus Advocacy-based Enhanced Care as Usual for Patients Experiencing IPV

Recruiting
  • VA Boston Healthcare System, Boston
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT06906302

Targeted Accelerated TMS for Post-Traumatic Stress Disorder

Recruiting
  • Brigham and Women's Hospital, Boston
Ages 18 to 65 · All sexes · Updated Aug 13, 2026 · NCT07245641

Reducing Psychological Barriers to PrEP Persistence Among Pregnant and Postpartum Women in Cape Town, South Africa

RecruitingHealthy volunteers welcome
  • Boston University, Boston
Ages 15 and older · Women · Updated Jul 17, 2026 · NCT05624931

Stepped Care for Posttraumatic Stress Disorder Study

Recruiting
  • Boston Medical Center, Boston
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT06947538

Evaluating Interventions for Intimate Partner Violence Use in Washington State

Recruiting
  • BU Chobanian & Avedisian School of Medicine, Psychiatry, Boston
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT06526247

CO2 Reactivity as a Biomarker of Non-Response to Exposure-Based Therapy

Recruiting
  • Boston University, Boston
Ages 18 to 70 · All sexes · Updated Jun 10, 2026 · NCT05467683

Treatment for Antepartum Posttraumatic Stress Disorder/PTSD Study

Recruiting
  • Boston Medical Center and remote, Boston
Ages 18 to 50 · Women · Updated May 28, 2026 · NCT05486793

Self-Help Cognitive Processing Therapy (CPT)/Women Veterans Network (WoVeN) Study

Recruiting
  • Fully online study, Boston
Ages 18 and older · Women · Updated May 27, 2026 · NCT07250061

Mismatch vs. Standard Intervention During Memory Reconsolidation Blockade With Propranolol: Effect on Psychophysiological Reactivity During Traumatic Imagery

RecruitingPhase 4
  • Massachusetts General Hospital Home Base Program, Charlestown · 1 mi away
Ages 18 to 65 · All sexes · Updated May 6, 2026 · NCT05853627

REVEAL Study - Diagnostic Testing for PTSD Using the Senseye Diagnostic Tool

RecruitingPhase 3Healthy volunteers welcome
  • Lindus Health (Virtual Study Site), Boston
Ages 18 and older · All sexes · Updated Apr 29, 2026 · NCT07280065

Enhancing PTSD Treatment Outcomes by Improving Patient-Provider Communication

Recruiting
  • National Center for PTSD at VA Boston Healthcare System, Boston
Ages 18 and older · All sexes · Updated Apr 1, 2026 · NCT06088303

A Study of a Novel EEG Neurofeedback System for PTSD Treatment

Recruiting
  • Boston VA Healthcare System, Boston
Ages 18 to 65 · All sexes · Updated Apr 1, 2026 · NCT06770998

Family Involvement in Treatment for PTSD (FIT-PTSD): A Brief, Feasible Method for Enhancing Outcomes, Retention, and Engagement

Recruiting
  • VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston
Ages 18 and older · All sexes · Updated Mar 20, 2026 · NCT05267665

A Mixed Methods Pilot Trial of the STEP Home Workshop to Improve Reintegration and Reduce Suicide Risk for Recently Transitioned Veterans

RecruitingHealthy volunteers welcome
  • VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston
Ages 18 to 65 · All sexes · Updated Mar 6, 2026 · NCT05995678

Determining the Benefits of Exercise on Cardiovascular Risk in PTSD

Recruiting
  • Massachusetts General Hospital, Boston
Ages 18 to 65 · All sexes · Updated Dec 2, 2025 · NCT07260032

Mechanisms Underlying Efficacy of Prolonged Exposure

Recruiting
  • MGH, Boston
Ages 18 and older · All sexes · Updated Nov 13, 2025 · NCT05788302

Facilitation of Extinction Retention and Reconsolidation Blockade by IV Allopregnanolone in PTSD.

RecruitingPhase 2Healthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 to 55 · All sexes · Updated Nov 5, 2025 · NCT07079761

Impact of Cognitive Behavioral Therapy on PTSD-CVD Link

Recruiting
  • Massachusetts General Hospital, Boston
Ages 18 to 65 · All sexes · Updated Sep 25, 2025 · NCT06429293

Mechanisms Underlying the Efficacy of Prolonged Exposure

Recruiting
  • VA Boston Healthcare System, Boston
Ages 18 to 90 · All sexes · Updated Apr 8, 2025 · NCT05663151

About Post-Traumatic Stress Disorder

 You can get Post-Traumatic Stress Disorder (PTSD) after experiencing a traumatic event. PTSD starts at different times for different people.

More about Post-Traumatic Stress Disorder on MedlinePlus

Post-Traumatic Stress Disorder trials in other cities

Other studies in Boston

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.