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Head and Neck Cancer clinical trials in Dallas, TX

12 studies for Head and Neck Cancer are looking for participants at sites in and around Dallas (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • UT Southwest Simmons Cancer Center, Dallas
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

DESTINY-PANTUMOUR04

RecruitingObservational study
  • Research Site, Dallas
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

Building a Renewed ImaGe After Head & Neck Cancer Treatment (BRIGHT) Multi-Site RCT

Recruiting
  • University of Texas Southwestern, Dallas
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT05442957

First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Texas Oncology-Baylor Charles A. Sammons Cancer Center, Dallas
  • University of Texas Southwestern, Dallas
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT05768139

A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements

RecruitingPhase 1/2
  • UT Southwestern Medical Center, Dallas
Ages 12 and older · All sexes · Updated May 27, 2026 · NCT03093116

A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma

RecruitingPhase 3
  • GSK Investigational Site, Dallas
Ages 18 and older · All sexes · Updated May 26, 2026 · NCT06256588

Invert-Prospective Phase II Randomized Trial of Involved Nodal Versus Elective Neck RadioTherapy

RecruitingPhase 2
  • UT Southwestern Medical Center, Dallas
Ages 18 to 99 · All sexes · Updated Apr 17, 2026 · NCT06477692

Stereotactic MRI-guided Focused Ultrasound Mesencephalotomy

Recruiting
  • The University of Texas Southwestern Medical Center, Dallas
Ages 18 to 85 · All sexes · Updated Feb 12, 2026 · NCT07405645

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Dallas
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

A Study to Evaluate TROP2 ADC LCB84 Single Agent and in Combination With an Anti-PD-1 Ab in Advanced Solid Tumors

RecruitingPhase 1/2
  • Mary Crowley Cancer Research, Dallas
  • University of Texas Southwestern Medical Center, Dallas
Ages 18 and older · All sexes · Updated Sep 24, 2025 · NCT05941507

Prospective Data Registry and Quality of Life Assessment of Patients Undergoing Radiotherapy With the RefleXion Medical Radiotherapy System

RecruitingObservational study
  • UT Southwestern, Dallas
All ages · All sexes · Updated Aug 15, 2025 · NCT05406167

About Head and Neck Cancer

Head and neck cancer includes cancers of the mouth, nose, sinuses, salivary glands, throat, and lymph nodes. Read the different symptoms of each type.

More about Head and Neck Cancer on MedlinePlus

Head and Neck Cancer trials in other cities

Other studies in Dallas

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.