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Prostate Cancer clinical trials in Detroit, MI

22 studies for Prostate Cancer are looking for participants at sites in and around Detroit (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

The Vanguard Study: Testing a New Way to Screen for Cancer

RecruitingHealthy volunteers welcome
  • Henry Ford Hospital, Detroit
  • Henry Ford Medical Center - Detroit Northwest, Detroit
Ages 45 to 75 · All sexes · Updated Oct 5, 2026 · NCT06995898

Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial

RecruitingPhase 3
  • Henry Ford Hospital, Detroit
Ages 18 and older · Men · Updated Oct 2, 2026 · NCT07200830

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Henry Ford Hospital, Detroit
  • Henry Ford Health Saint John Hospital, Detroit
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

RecruitingPhase 2
  • Henry Ford Hospital, Detroit
  • Henry Ford Health Saint John Hospital, Detroit
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT03866382

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

RecruitingPhase 3
  • Henry Ford Hospital ( Site 0015), Detroit
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06136650

Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer

RecruitingPhase 1/2
  • Research Site, Detroit
Ages 18 to 130 · Men · Updated Sep 25, 2026 · NCT07181161

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

RecruitingPhase 1
  • Barbara Ann Karmanos Cancer Institute, Detroit
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07114601

Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

RecruitingPhase 3
  • Karmanos Cancer Institute, Detroit
Ages 18 to 100 · Men · Updated Sep 22, 2026 · NCT06855277

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

RecruitingPhase 3
  • Henry Ford Hospital ( Site 0035), Detroit
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT06925737

Sacral Neuromodulation for Male Overactive Bladder (MOAB)

Recruiting
  • Wayne State University, Detroit
Ages 18 and older · Men · Updated Sep 14, 2026 · NCT06511141

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

RecruitingPhase 3
  • Henry Ford Hospital, Detroit
Ages 18 and older · Men · Updated Sep 10, 2026 · NCT05946213

A Phase 1b/2a Study of Pocenbrodib as Monotherapy and in Combination With Darolutamide in Participants With mCRPC

RecruitingPhase 1/2
  • Karmanos Cancer Institute, Detroit
Ages 18 and older · Men · Updated Aug 20, 2026 · NCT06785636

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

RecruitingPhase 3
  • Wayne State University/Karmanos Cancer Institute, Detroit
  • Henry Ford Hospital, Detroit
Ages 18 and older · Men · Updated Jul 14, 2026 · NCT06592924

Study of ORIC-944 in Patients With Metastatic Prostate Cancer

RecruitingPhase 1
  • Karmanos, Detroit
Ages 18 and older · Men · Updated Jul 9, 2026 · NCT05413421

Culturally Adapting an Intervention to Increase Genetic Testing in African American Cancer Survivors

Recruiting
  • Karmanos Cancer Institute, Detroit
Ages 20 to 79 · All sexes · Updated Jun 23, 2026 · NCT07436078

International Registry for Men With Advanced Prostate Cancer (IRONMAN)

RecruitingObservational study
  • Karmanos Cancer Institute, Detroit
Ages 21 and older · Men · Updated May 22, 2026 · NCT03151629

Ruxolitinib and Enzalutamide for the Treatment of Metastatic Castration-Resistant Prostate Cancer

RecruitingPhase 1/2
  • Karmanos Cancer Institute, Detroit
Ages 18 and older · Men · Updated May 5, 2026 · NCT06616155

Gedatolisib in Combination With Darolutamide in Metastatic Castration-Resistant Prostate Cancer

RecruitingPhase 1/2
  • Barbara Ann Karmanos Cancer Institute, Detroit
Ages 18 and older · Men · Updated Apr 13, 2026 · NCT06190899

A Comparison of Radical Prostatectomy and Precision Prostatectomy in Low- and Intermediate-risk Prostate Cancers.

Recruiting
  • Henry Ford Health, Detroit
All ages · Men · Updated Jan 16, 2026 · NCT07348367

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

RecruitingPhase 1/2
  • Research Site 129, Detroit
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05914116

Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

RecruitingPhase 3
  • Wayne State University/Karmanos Cancer Institute, Detroit
  • Henry Ford Hospital, Detroit
Ages 18 and older · Men · Updated Sep 11, 2025 · NCT03678025

About Prostate Cancer

Prostate cancer is one of the most common types of cancer among American men. The risk goes up as men age. Learn about symptoms, tests, and treatment.

More about Prostate Cancer on MedlinePlus

Prostate Cancer trials in other cities

Other studies in Detroit

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.