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Endometrial Cancer clinical trials in Columbus, OH

25 studies for Endometrial Cancer are looking for participants at sites in and around Columbus (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

RecruitingPhase 2
  • Ohio State University Comprehensive Cancer Center, Columbus
  • Mount Carmel East Hospital, Columbus
  • Columbus Oncology and Hematology Associates Inc, Columbus
  • and 13 more
All ages · All sexes · Updated Oct 2, 2026 · NCT05564377

Testing Different Amounts of the Combination of Drugs M1774 and ZEN-3694 for the Treatment of Recurrent Ovarian and Endometrial Cancer

RecruitingPhase 1
  • Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · Women · Updated Oct 2, 2026 · NCT05950464

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

RecruitingPhase 3
  • Ohio State University Comprehensive Cancer Center, Columbus
  • Columbus Oncology and Hematology Associates Inc, Columbus
  • Riverside Methodist Hospital, Columbus
  • and 8 more
Ages 18 and older · Women · Updated Oct 2, 2026 · NCT07198074

Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma

RecruitingPhase 2
  • Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · Women · Updated Sep 28, 2026 · NCT05112601

Study of REGN4018 (Ubamatamab) Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) Cancers

RecruitingPhase 1/2
  • The Ohio State University Wexner Medical Center, Columbus
Ages 18 and older · Women · Updated Sep 25, 2026 · NCT03564340

A Study to Find Out How Safe REGN5668 is and How Well it Works In Adult Women When Given With Either Cemiplimab, or Cemiplimab + Fianlimab, or Ubamatamab

RecruitingPhase 1/2
  • The Ohio State University Wexner Medical Center, Columbus
Ages 18 and older · Women · Updated Sep 24, 2026 · NCT04590326

Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER

RecruitingPhase 2
  • Ohio State University Comprehensive, Columbus
Ages 18 and older · Women · Updated Sep 24, 2026 · NCT05640999

Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)

RecruitingPhase 2
  • Research Site, Columbus
Ages 18 to 130 · All sexes · Updated Sep 23, 2026 · NCT05489211

A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)

RecruitingPhase 3
  • The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive C ( Site 6007), Columbus
Ages 18 and older · Women · Updated Sep 17, 2026 · NCT06952504

A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy in Patients With Recurring Uterine Cancer

RecruitingPhase 3
  • Ohio State University, Hilliard · 10 mi away
Ages 18 and older · Women · Updated Sep 17, 2026 · NCT06340568

A Study of Sofe-M in Participants With Selected Advanced Solid Tumors

RecruitingPhase 1
  • The Ohio State University (OSU) Wexner Medical Center, Columbus
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06400472

Phase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid Tumors

RecruitingPhase 1
  • The Ohio State University, Columbus
Ages 15 and older · All sexes · Updated Aug 25, 2026 · NCT06276491

Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors

RecruitingPhase 1/2
  • Research Site, Columbus
Ages 18 to 130 · All sexes · Updated Aug 21, 2026 · NCT05797168

A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma

RecruitingPhase 2
  • Ohio State University, Hilliard · 10 mi away
Ages 18 and older · Women · Updated Aug 21, 2026 · NCT05548296

A Study of MUC16-Directed Antibody Drug Conjugate HWK-016 in Participants With Advanced Solid Tumors.

RecruitingPhase 1
  • Ohio State University Wexner Medical Center, Columbus
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07470853

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • The Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT05592626

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

RecruitingPhase 1/2
  • Ohio State University Comprehensive Cancer Center (OSUCCC)- The James Cancer Hospital and Solove Research Institute, Columbus
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT05579366

Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)

RecruitingPhase 3
  • Research Site, Columbus
  • Research Site, Hilliard · 10 mi away
Ages 18 and older · Women · Updated Jul 29, 2026 · NCT07044336

First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Stefanie Spielman Comprehensive Breast Center, Columbus
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT05768139

A Study of LY4175408 in Participants With Advanced Cancer

RecruitingPhase 1
  • The Ohio State University (OSU) Wexner Medical Center, Columbus
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT07046923

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

RecruitingPhase 1/2
  • Stefanie Spielman Comprehensive Breast Center, Columbus
Ages 18 and older · All sexes · Updated Mar 27, 2026 · NCT06395519

A Study of MT-4561 in Patients With Various Advanced Solid Tumors

RecruitingPhase 1/2
  • The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Dec 11, 2025 · NCT06943521

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Columbus
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Study of Navtemadlin as Maintenance Therapy in TP53WT Advanced or Recurrent Endometrial Cancer

RecruitingPhase 2/3
  • OhioHealth Institute, Columbus
Ages 18 and older · Women · Updated May 2, 2024 · NCT05797831

Endometrial Cancer trials in other cities

Other studies in Columbus

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.