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Glioma clinical trials in Columbus, OH

15 studies for Glioma are looking for participants at sites in and around Columbus (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

RecruitingPhase 1/2
  • Nationwide Children's Hospital, Columbus
12 Months – 21 Years · All sexes · Updated Oct 1, 2026 · NCT05099003

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

RecruitingPhase 2
  • Ohio State University, Columbus
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07326566

ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas

RecruitingPhase 2
  • Nationwide Children's Hospital, Columbus
12 Months – 39 Years · All sexes · Updated Sep 21, 2026 · NCT06838676

Targeted Pediatric High-Grade Glioma Therapy

RecruitingObservational study
  • Nationwide Children's Hospital, Columbus
12 Months – 39 Years · All sexes · Updated Sep 8, 2026 · NCT05839379

Study of Olutasidenib and Temozolomide in HGG

RecruitingPhase 2
  • Nationwide Children's Hospital, Columbus
Ages 12 to 39 · All sexes · Updated Sep 1, 2026 · NCT06161974

PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

RecruitingPhase 2
  • Nationwide Children's Hospital, Columbus
Ages 3 to 39 · All sexes · Updated Aug 24, 2026 · NCT05096481

A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

RecruitingPhase 2
  • The Ohio State University Comprehensive Cancer Center (OSUCCC) - The James Cancer Hospital and Solove Research Institute, Columbus
Ages 8 and older · All sexes · Updated Jul 27, 2026 · NCT05503797

Alpha Radiation Emitters Device (DaRT) for the Treatment of Recurrent Glioblastoma

Recruiting
  • Ohio State University Medical Center, Columbus
Ages 18 to 85 · All sexes · Updated Jul 21, 2026 · NCT06910306

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

RecruitingPhase 1/2
  • Nationwide Children's Hospital, Columbus
Ages 4 to 39 · All sexes · Updated Jul 20, 2026 · NCT05278208

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

RecruitingEarly phase 1Healthy volunteers welcome
  • Nationwide Children's Hospital, Columbus
Ages 1 to 21 · All sexes · Updated Jun 29, 2026 · NCT06333899

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

RecruitingPhase 2
  • Nationwide Children's Hospital, Columbus
12 Months – 39 Years · All sexes · Updated May 29, 2026 · NCT05843253

Anti-GARP Chimeric Antigen Receptor T Cell Therapy for the Treatment of Recurrent Grade III or IV Gliomas

RecruitingPhase 1
  • Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated May 8, 2026 · NCT06964737

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

RecruitingPhase 1/2
  • Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT06810544

A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion

RecruitingEarly phase 1
  • Nationwide Children's Hospital, Columbus
Up to age 21 · All sexes · Updated Mar 18, 2026 · NCT04655404

Phase 1 Study of Locoregional Injections of Ex Vivo Expanded Natural Killer Cells

RecruitingPhase 1
  • Nationwide Children's Hospital, Columbus
12 Months – 39 Years · All sexes · Updated May 13, 2025 · NCT04254419

Glioma trials in other cities

Other studies in Columbus

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.