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Heart Valve Diseases clinical trials in Cleveland, OH

10 studies for Heart Valve Diseases are looking for participants at sites in and around Cleveland (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Transcatheter Tricuspid Valve Replacement With the Medtronic Intrepid™ Transcatheter Tricuspid Valve Replacement (TTVR) System in Severe Tricuspid Regurgitation

Recruiting
  • Cleveland Clinic Foundation, Cleveland
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07321899

Medtronic Cardiac Surgery PMCF Registry

RecruitingObservational study
  • University Hospitals Cleveland, Cleveland
All ages · All sexes · Updated Sep 25, 2026 · NCT04073420

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

Recruiting
  • University Hospitals Cleveland Medical Center, Cleveland
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT03242642

Global Multicenter Registry on Transcatheter TRIcuspid Valve RePLACEment

RecruitingObservational study
  • Cleveland Clinic, Cleveland
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06033274

Abbott Structural Heart Device Registry

RecruitingObservational study
  • The Cleveland Clinic Foundation, Cleveland
All ages · All sexes · Updated Sep 1, 2026 · NCT06590467

Longitudinal Validation of CIRC Technologies

RecruitingObservational studyHealthy volunteers welcome
  • Cleveland Clinic, Cleveland
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT07081711

Development of CIRC Technologies

RecruitingObservational studyHealthy volunteers welcome
  • Cardiovascular Innovation Research Center, Cleveland
Ages 18 and older · All sexes · Updated May 8, 2026 · NCT05654272

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

Recruiting
  • Cleveland Clinic, Cleveland
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152

Comparative Imaging Assessment of Valvular Heart Disease

RecruitingObservational study
  • Cleveland Clinic, Cleveland
Ages 18 to 90 · All sexes · Updated Jan 13, 2026 · NCT04126018

CORCYM Mitral, Aortic aNd Tricuspid Post-maRket Study in a reAl-world Setting

RecruitingObservational study
  • University Hospitals Cleveland, Cleveland
  • Cleveland Clinic, Cleveland
All ages · All sexes · Updated Mar 6, 2024 · NCT05002543

About Heart Valve Diseases

Heart valve disease happens when one or more of your heart valves do not open or close correctly. This can affect your blood flow and strain your heart.

More about Heart Valve Diseases on MedlinePlus

Heart Valve Diseases trials in other cities

Other studies in Cleveland

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.