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Stroke clinical trials in Charleston, SC

18 studies for Stroke are looking for participants at sites in and around Charleston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial

RecruitingPhase 3
  • Medical University of South Carolina, Charleston
Ages 18 to 79 · All sexes · Updated Oct 2, 2026 · NCT05611242

Repetitive Transcranial Magnetic Stimulation, a Form of Non-invasive Brain Stimulation, as a Possible Treatment for Post-stroke Fatigue

RecruitingPhase 2
  • Ralph H. Johnson VA Medical Center, Charleston
Ages 34 to 80 · All sexes · Updated Sep 14, 2026 · NCT05584124

Post-stroke Pain tAN-fMRI

Recruiting
  • 30 Bee Street, Charleston
  • Medical University of South Carolia, Charleston
Ages 18 to 80 · All sexes · Updated Sep 11, 2026 · NCT07144436

Telerehabilitation In The Home After Stroke

Recruiting
  • Medical University of South Carolina, Charleston
Ages 18 to 80 · All sexes · Updated Sep 9, 2026 · NCT06682429

Escitalopram and Language Intervention for Subacute Aphasia

RecruitingPhase 2
  • Medical University of South Carolina, Charleston
Ages 18 to 99 · All sexes · Updated Sep 3, 2026 · NCT03843463

Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials

RecruitingObservational study
  • Medical University of South Carolina (MUSC), Charleston
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT05338697

Combining rTMS & Aerobic Exercise to Treat Depression and Improve Post-Stroke Walking

Recruiting
  • Medical University of South Carolina, Charleston
Ages 21 and older · All sexes · Updated Aug 4, 2026 · NCT07050355

Superiority Trial of Aphasia-focused Rehabilitation With tDCS Stimulation

RecruitingPhase 2/3
  • Medical University of South Carolina, Charleston
Ages 25 to 80 · All sexes · Updated Jul 21, 2026 · NCT07688551

Accelerated rTMS vs. Sham for Stroke Apathy

RecruitingPhase 1/2
  • Medical University of South Carolina Brain Stimulation Lab, Charleston
Ages 40 and older · All sexes · Updated Jul 8, 2026 · NCT07113067

Emotional Recovery Post-Stroke

Recruiting
  • Medical University of South Carolina, Charleston
Ages 21 and older · All sexes · Updated Jun 18, 2026 · NCT06782321

Weight Loss and ExeRcise for Post-stroke Veterans

Recruiting
  • Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston
Ages 40 to 80 · All sexes · Updated May 15, 2026 · NCT06322030

Exoskeleton for Balance

Recruiting
  • Medical University of South Carolina, Charleston
Ages 21 and older · All sexes · Updated May 12, 2026 · NCT07356011

EMPOWER: Effects of Weight Loss and Exercise Post-stroke

Recruiting
  • College of Health Professions, Charleston
Ages 35 to 85 · All sexes · Updated Apr 15, 2026 · NCT05901675

Multisensory Augmentation for Post-stroke Standing Balance

RecruitingEarly phase 1
  • Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston
Ages 21 and older · All sexes · Updated Jan 6, 2026 · NCT05760885

Stroke Thrombectomy and Aneurysm Registry

RecruitingObservational study
  • Medical University of South Carolina, Charleston
Ages 1 to 120 · All sexes · Updated Dec 24, 2025 · NCT04994756

Physical Capacity Building for Chronic Stroke

Recruiting
  • Medical University of South Carolina, Charleston
Ages 18 to 80 · All sexes · Updated Dec 8, 2025 · NCT07039305

EMG-Controlled Game to Retrain Upper Extremity Muscle Activation Patterns Following Stroke

RecruitingHealthy volunteers welcome
  • Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston
Ages 18 and older · All sexes · Updated Aug 26, 2025 · NCT05628324

Encore PFO Closure Device - The PerFOrm Trial

Recruiting
  • Medical University of South Carolina Gazes Research Institute, Charleston
Ages 18 to 60 · All sexes · Updated Sep 19, 2024 · NCT05537753

About Stroke

A stroke happens when there is a loss of blood flow to part of the brain. Immediate treatment may save a life and increase the chances for successful recovery.

More about Stroke on MedlinePlus

Stroke trials in other cities

Other studies in Charleston

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.