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Stroke clinical trials in Philadelphia, PA

18 studies for Stroke are looking for participants at sites in and around Philadelphia (within about 30 miles). Open a study to see who can join and how to contact the study team.

CoMind Early Feasibility Study

RecruitingObservational study
  • University of Pennsylvania Hospital, Philadelphia
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT06368648

Treatment of Acute Ischemic Stroke (ReMEDy2 Trial)

RecruitingPhase 2/3
  • The Hospital of the University of Pennsylvania, Philadelphia
Ages 18 to 90 · All sexes · Updated Sep 14, 2026 · NCT05065216

Telerehabilitation In The Home After Stroke

Recruiting
  • Jefferson Moss Rehabilitation Research Institute, Elkins Park · 9 mi away
Ages 18 to 80 · All sexes · Updated Sep 9, 2026 · NCT06682429

An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)

RecruitingPhase 3
  • Perelman School of Medicine, Philadelphia
Ages 18 to 100 · All sexes · Updated Sep 4, 2026 · NCT07517263

tACS to Enhance Language Abilities

RecruitingHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 18 to 85 · All sexes · Updated Aug 24, 2026 · NCT06092814

Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials

RecruitingObservational study
  • Pennsylvania Hospital, Philadelphia
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT05338697

A Pilot Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368, a FAAH/MAGL Inhibitor, in Participants With Post-Stroke Spasticity (The STIPS Study)

RecruitingPhase 2
  • Jeffersi=on Moss Magee Rehabilitation, Elkins Park · 9 mi away
Ages 18 to 80 · All sexes · Updated Jul 29, 2026 · NCT07704840

Pilot/Pivotal Study of DBS+Rehab After Stroke

Recruiting
  • Thomas Jefferson University, Philadelphia
Ages 21 and older · All sexes · Updated Jul 20, 2026 · NCT05701280

Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

RecruitingPhase 3
  • University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Jun 26, 2026 · NCT04045665

Transcranial Magnetic Stimulation + Language Therapy to Treat Subacute Aphasia

RecruitingPhase 2Mentions payment for participants
  • University of Pennsylvania, Philadelphia
Ages 18 to 85 · All sexes · Updated Jun 18, 2026 · NCT06968663

Robotic Rehabilitation of the Upper Limb in Subacute Stroke

Recruiting
  • Jefferson Moss-Magee Rehabilitation, Department of PMR, Elkins Park · 9 mi away
Ages 18 to 85 · All sexes · Updated Apr 23, 2026 · NCT06839482

Neuralert Stroke Monitor Trial

Recruiting
  • Hospital of the University of Pennsylvania, Philadelphia
Ages 22 and older · All sexes · Updated Apr 1, 2026 · NCT07362303

Optimizing the Prehospital Use of Stroke Systems of Care-Reacting to Changing Paradigms-Implementation (OPUS-i)

Recruiting
  • 3401 N Broad street, Philadelphia
Ages 18 and older · All sexes · Updated Mar 12, 2026 · NCT06530693

Transcranial Magnetic Stimulation + Language Therapy to Treat Mild Aphasia

RecruitingPhase 2Mentions payment for participants
  • University of Pennsylvania, Philadelphia
Ages 40 to 85 · All sexes · Updated Mar 5, 2026 · NCT06842745

North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)

RecruitingObservational studyHealthy volunteers welcome
  • The Children's Hospital of Philadelphia, Philadelphia
All ages · All sexes · Updated Feb 4, 2026 · NCT01694940

The Neuralert Stroke Monitor Pilot Trial

Recruiting
  • Hospital of the University of Pennsylvania, Philadelphia
Ages 22 and older · All sexes · Updated Jan 20, 2026 · NCT06368193

Stroke Thrombectomy and Aneurysm Registry

RecruitingObservational study
  • Thomas Jefferson University, Philadelphia
Ages 1 to 120 · All sexes · Updated Dec 24, 2025 · NCT04994756

Timing Impact of Early vs. Late Cranioplasty on Hemicraniectomy Outcomes

RecruitingHealthy volunteers welcome
  • Thomas Jefferson University Hospitals, Philadelphia
Ages 18 and older · All sexes · Updated Jul 23, 2025 · NCT06632587

About Stroke

A stroke happens when there is a loss of blood flow to part of the brain. Immediate treatment may save a life and increase the chances for successful recovery.

More about Stroke on MedlinePlus

Stroke trials in other cities

Other studies in Philadelphia

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.