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Chronic Pain clinical trials in Chicago, IL

13 studies for Chronic Pain are looking for participants at sites in and around Chicago (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

ARPA-H Smart Band-Aid to Measure Chronic Pain in Women

RecruitingObservational studyHealthy volunteers welcome
  • Northwestern University Feinberg School of Medicine, Chicago
Ages 18 and older · Women · Updated Sep 14, 2026 · NCT06994988

Evaluate the Impact of Targeted Physical Activity on Clinically Debilitated Dialysis Patients.

Recruiting
  • University of Illinois at Chicago, Chicago
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06374537

A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Osteoarthritis Pain

RecruitingPhase 2
  • Northwestern University, Chicago
Ages 40 and older · All sexes · Updated Sep 4, 2026 · NCT07641517

A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Chronic Low Back Pain

RecruitingPhase 2
  • Northwestern University, Chicago
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07641504

(2R,6R)-Hydroxynorketamine for the Treatment of Neuropathic Pain

RecruitingPhase 1/2
  • Rush University Medical Center, Chicago
Ages 18 to 75 · All sexes · Updated Aug 3, 2026 · NCT05864053

A Bionic Breast Project Using Neuroprosthesis to Reduce Chronic Pain After Mastectomy

Recruiting
  • University of Chicago Medicine Comprehensive Cancer Center, Chicago
Ages 18 and older · Women · Updated Apr 27, 2026 · NCT06382272

Diabetic Neuropathy in Spinal Cord Stimulator Patients

RecruitingObservational study
  • University of Chicago Medical Center, Chicago
Ages 18 and older · All sexes · Updated Feb 5, 2026 · NCT04687215

Intermittent Dosing of Dorsal Root Ganglion Stimulation as an Alternate Paradigm to Continuous Low-Frequency Therapy

Recruiting
  • Rush University Medical Center, Chicago
Ages 18 to 90 · All sexes · Updated Jan 21, 2026 · NCT04909138

A Longitudinal Study Looking at the Prevalence, Risk Factors & Consequences of Persistent Post-surgical Pain in Children

RecruitingObservational studyHealthy volunteers welcome
  • Lurie Children's Hospital of Chicago, Chicago
Up to age 16 · All sexes · Updated Oct 23, 2025 · NCT06354699

Preventing the Development of Chronic Pain: Treating PTSD at Acute Pain Onset

Recruiting
  • Rush University Medical Center, Chicago
Ages 18 to 70 · All sexes · Updated Oct 20, 2025 · NCT05700279

Evaluating the Impact of Focused Muscle Contraction Therapy in U.S. Veterans

Recruiting
  • University of Illinois at Chicago, Chicago
Ages 18 and older · All sexes · Updated Sep 19, 2025 · NCT05094297

Comparing Single-Session Therapies for Chronic Pain

Recruiting
  • Rush University Medical Center, Chicago
Ages 18 and older · All sexes · Updated Jul 15, 2025 · NCT07008105

VR and Cooled Genicular Nerve Radio Frequency Ablation for Chronic Knee Pain

Recruiting
  • Northwestern Medicine Pain Center, Chicago
Ages 18 and older · All sexes · Updated Mar 28, 2024 · NCT06336447

About Chronic Pain

Chronic pain lasts longer than three months or the time in which you should have healed. It is not always curable, but treatments can help.

More about Chronic Pain on MedlinePlus

Chronic Pain trials in other cities

Other studies in Chicago

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.