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Myelodysplastic Syndromes clinical trials in Columbus, OH

14 studies for Myelodysplastic Syndromes are looking for participants at sites in and around Columbus (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment (Cedazuridine-Decitabine) for Higher-Risk Myelodysplastic Syndrome (MDS) With IDH2 Mutation (A MyeloMATCH Treatment Trial)

RecruitingPhase 2
  • Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06577441

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

RecruitingPhase 2
  • Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05564390

Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia

RecruitingPhase 1/2
  • The Ohio State University, Columbus
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT05320198

Collection of Tissue Samples for Cancer Research

RecruitingObservational study
  • Ohio State University, Columbus
2 Months · All sexes · Updated Sep 16, 2026 · NCT00900198

Phase 1 Study of AUTX-703 in Relapsed/Refractory AML and MDS

RecruitingPhase 1
  • Ohio State University, The James Comprehensive Cancer, Columbus
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT06846606

Ivosidenib (IVO) Monotherapy and Azacitidine (AZA) Monotherapy in Patients With Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS) With an IDH1 Mutation

RecruitingPhase 3
  • Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06465953

Study of R289 in Patients With Lower-risk Myelodysplastic Syndromes (LR MDS)

RecruitingPhase 1/2
  • The Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT05308264

A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)

RecruitingPhase 2/3
  • Ohio State University Comprehensive Cancer Center (OSUCCC) - The James Cancer Hospital and Solove Research Institute, Columbus
Ages 18 and older · All sexes · Updated Apr 30, 2026 · NCT04256317

Expanded/Activated Gamma Delta T-cell Infusion Following Hematopoietic Stem Cell Transplantation and Post-transplant Cyclophosphamide

RecruitingPhase 1
  • Ohio State University Medical Center, Columbus
Ages 18 to 65 · All sexes · Updated Mar 25, 2026 · NCT03533816

A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)

RecruitingPhase 1/2
  • The Ohio State University Comprehensive Cancer Center, Columbus
Ages 12 and older · All sexes · Updated Mar 24, 2026 · NCT04988555

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Columbus
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

A Study of BH-30236 in Relapsed/ Refractory Acute Myelogenous Leukemia and Higher Risk Myelodysplastic Syndrome

RecruitingPhase 1
  • The Ohio State University Wexner Medical Center - James Cancer Hosp, Columbus
Ages 18 and older · All sexes · Updated Sep 24, 2025 · NCT06501196

HPC Offered for PRESERVE Expansion

RecruitingObservational study
  • The Ohio State University Medical Center, Columbus
Ages 12 to 80 · All sexes · Updated Aug 28, 2025 · NCT07145411

About Myelodysplastic Syndromes

Myelodysplastic Syndromes (MDS) are rare. They are sometimes found during a routine blood test. Learn symptoms, risk factors, and treatment options.

More about Myelodysplastic Syndromes on MedlinePlus

Myelodysplastic Syndromes trials in other cities

Other studies in Columbus

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.