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Bladder Cancer clinical trials in Columbus, OH

18 studies for Bladder Cancer are looking for participants at sites in and around Columbus (within about 30 miles). Open a study to see who can join and how to contact the study team.

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

RecruitingPhase 2
  • Riverside Methodist Hospital, Columbus
  • Grant Medical Center, Columbus
  • Doctors Hospital, Columbus
  • and 1 more
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06770582

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

RecruitingPhase 2
  • Ohio State University Comprehensive Cancer Center, Columbus
  • Mount Carmel East Hospital, Columbus
  • Columbus Oncology and Hematology Associates Inc, Columbus
  • and 11 more
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT03866382

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

RecruitingPhase 3
  • The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive Cancer -T, Columbus
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07218380

Personalized Cancer Vaccine (PCV) Strategy in Patients With Solid Tumors and Molecular Residual Disease

RecruitingPhase 1
  • Ohio State University, Columbus
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT06529822

Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBC

RecruitingPhase 2
  • Ohio State University, Columbus
  • Central Ohio Urology Group (US Urology Partners), Gahanna · 7 mi away
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06567743

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Ohio State University Comprehensive Cancer Center, Columbus
  • Mount Carmel East Hospital, Columbus
  • The Mark H Zangmeister Center, Columbus
  • and 8 more
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069

FORAGER-1: A Study of Vepugratinib (LY3866288; LOXO-435) in Participants With Cancer With a Change in a Gene Called FGFR3

RecruitingPhase 1
  • The Ohio State University (OSU), Columbus
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT05614739

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Study

RecruitingPhase 3
  • Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07097142

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • The Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT05592626

LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve

RecruitingPhase 1/2
  • Central Ohio Urology Group, Gahanna · 7 mi away
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT04752722

Testing the Addition of an Anti-Cancer Drug, Gemcitabine, to Usual Treatment (BCG Alone) in People Whose Non-Muscle Invasive Bladder Cancer (NMIBC) Came Back After Prior BCG Therapy

RecruitingPhase 3
  • Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT07000084

Comparison of Intravesical Therapy and Surgery as Treatment Options for Bladder Cancer 2

RecruitingObservational study
  • The Ohio State University, Columbus
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT07225127

Phase 2/3 Trial of Izalontamab Brengitecan vs Platinum-based Chemotherapy for Metastatic Urothelial Cancer With Disease Progression on or After Immunotherapy

RecruitingPhase 2/3
  • The James Outpatient Care West Campus, Columbus
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT07106762

A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

RecruitingPhase 2
  • The Ohio State University Comprehensive Cancer Center (OSUCCC) - The James Cancer Hospital and Solove Research Institute, Columbus
Ages 8 and older · All sexes · Updated Jul 27, 2026 · NCT05503797

A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2

RecruitingPhase 2
  • Ohio State University Hospital, Columbus
  • Ohio State University, Columbus
  • OSU Wexner Medical Center & James Cancer Hospital, Columbus
  • and 2 more
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT04879329

Blue Light Cystoscopy With Cysview® Registry

RecruitingObservational study
  • Ohio State University Wexner Medical Center, Columbus
  • Ohio State University, Columbus
Ages 18 and older · All sexes · Updated Dec 18, 2025 · NCT02660645

Futibatinib in Combination With Durvalumab Prior to Cystectomy for the Treatment of Muscle-Invasive Bladder Cancer Patients Who Are Ineligible for Cisplatin-based Therapy

RecruitingPhase 2
  • Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Dec 17, 2025 · NCT06263153

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Columbus
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

About Bladder Cancer

Bladder cancer symptoms range from lower back pain to blood in your urine. Read about important risk factors and find a list of treatments available

More about Bladder Cancer on MedlinePlus

Bladder Cancer trials in other cities

Other studies in Columbus

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.