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Bladder Cancer clinical trials in Irvine, CA

11 studies for Bladder Cancer are looking for participants at sites in and around Irvine (within about 30 miles). Open a study to see who can join and how to contact the study team.

Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial

RecruitingPhase 2
  • City of Hope at Irvine Lennar, Irvine
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07061964

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

RecruitingPhase 2
  • UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care, Irvine
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT06770582

Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer

RecruitingPhase 1/2
  • UCLA Hematology/Oncology - Irvine, Irvine
  • Chao Family Comprehensive Cancer Center and Ambulatory Care, Irvine
  • UCI Health - Irvine Infusion Pharmacy ACC, Irvine
  • and 2 more
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07421700

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

RecruitingPhase 3
  • Chao Family Comprehensive Cancer Center and Ambulatory Care (CIACC) - Irvine, Irvine
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07218380

A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors

RecruitingPhase 1
  • City of Hope at Irvine Lennar, Irvine
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07090499

Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBC

RecruitingPhase 2
  • City of Hope, Irvine
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06567743

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Study

RecruitingPhase 3
  • UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care, Irvine
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07097142

LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve

RecruitingPhase 1/2
  • University of California - Irvine Medical Center, Irvine
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT04752722

Testing the Addition of an Anti-Cancer Drug, Gemcitabine, to Usual Treatment (BCG Alone) in People Whose Non-Muscle Invasive Bladder Cancer (NMIBC) Came Back After Prior BCG Therapy

RecruitingPhase 3
  • UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care, Irvine
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT07000084

A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2

RecruitingPhase 2
  • Chao Family Comprehensive Cancer Center and Ambulatory Care, Irvine
  • Kaiser Permanente Alton/Sand Canyon Medical Offices, Irvine
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT04879329

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Irvine
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

About Bladder Cancer

Bladder cancer symptoms range from lower back pain to blood in your urine. Read about important risk factors and find a list of treatments available

More about Bladder Cancer on MedlinePlus

Bladder Cancer trials in other cities

Other studies in Irvine

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.