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Multiple Myeloma clinical trials in Irvine, CA

14 studies for Multiple Myeloma are looking for participants at sites in and around Irvine (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Study Evaluating the Prophylactic Use of Tocilizumab to Prevent Cytokine Release Syndrome With Ramantamig Administration in Participants With Relapsed/Refractory Multiple Myeloma

RecruitingPhase 2
  • City of Hope Orange County Lennar Foundation Cancer Center, Irvine
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07589634

A Study to Evaluate Adverse Events, Change in Disease Activity, Tolerability, and How Intravenous ABBV-438 Moves Through the Body in Adult Participants With Multiple Myeloma (MM)

RecruitingPhase 1
  • City of Hope - Orange County Lennar Foundation Cancer Center /ID# 279067, Irvine
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07409246

A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma or Previously Treated Amyloid Light-chain (AL) Amyloidosis

RecruitingPhase 1
  • City of Hope Orange County Lennar Foundation Cancer Center, Irvine
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT05652335

A Study Comparing JNJ-79635322 and Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma

RecruitingPhase 3
  • UC Irvine Health Chao Family Comprehensive Cancer Center and Ambulatory Care, Irvine
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07518186

A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma

RecruitingPhase 3
  • City of Hope Orange County Lennar Foundation Cancer Center, Irvine
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07258511

A Study of IBI3003 in Subjects With Relapsed or Refractory Multiple Myeloma

RecruitingPhase 1/2
  • City of Hope - Lennar, Irvine
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07336472

A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma

RecruitingPhase 3
  • City of Hope Orange County Lennar Foundation Cancer Center, Irvine
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05552222

Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in Participants With Previously Treated Multiple Myeloma

RecruitingPhase 3
  • City of Hope - Lennar Foundation Cancer Center, Irvine
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT07555938

AZD0305 as Monotherapy or in Combination With Anticancer Agents in Participants With Multiple Myeloma

RecruitingPhase 1/2
  • Research Site, Irvine
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT06106945

A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Multiple Myeloma Receiving T Cell Engaging Bi/Tri-specific Antibodies Intravenously (IV)/Subcutaneously (SC) Alone or in Combinations

RecruitingPhase 1/2
  • City of Hope - Orange County Lennar Foundation Cancer Center /ID# 277911, Irvine
Ages 18 and older · All sexes · Updated Jul 21, 2026 · NCT06892522

Elranatamab Post Trial Access Study for Participants With Multiple Myeloma (MM)

RecruitingPhase 4
  • UCI Health - Irvine Infusion Pharmacy ACC, Irvine
Ages 18 and older · All sexes · Updated Jul 1, 2026 · NCT06057402

A Multicenter Prospective Observational Cohort Study Evaluating the Impact of Cancer-Directed Treatment and Medication Use, Including Cannabis Use, in Multiple Myeloma Patients

RecruitingObservational studyHealthy volunteers welcome
  • City of Hope at Irvine Lennar, Irvine
Ages 18 and older · All sexes · Updated Feb 20, 2026 · NCT07225738

About Multiple Myeloma

Multiple myeloma is a cancer that begins in plasma cells, a type of white blood cell. Discover symptoms, diagnostic tests, and treatments for myeloma.

More about Multiple Myeloma on MedlinePlus

Multiple Myeloma trials in other cities

Other studies in Irvine

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.